Toxicological Risk Assessment of Chemicals: A Practical Guide

1st Edition

Elsa Nielsen, Grete Ostergaard, John Christian Larsen

CRC Press
Published February 21, 2008
Reference - 448 Pages - 43 B/W Illustrations
ISBN 9780849372650 - CAT# 7265

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Unlike many existing books on toxicology that cover either toxicity of a particular substance or toxicity of chemicals on particular organ systems, Toxicological Risk Assessment of Chemicals: A Practical Guide lays out the principle activities of conducting a toxicological risk assessment, including international approaches and methods for the risk assessment of chemical substances. It illustrates each step in the process: hazard identification, a dose response assessment, and exposure assessment. The book also summarizes the basic concepts of interaction of chemicals in mixtures and discusses various approaches to testing such mixtures.


  • Addresses standards from all international regulatory agencies
  • Presents the steps in risk assessment, including hazard identification, exposure assessment, and risk characterization
  • Covers the assessment of multiple chemical exposures or chemical mixtures
  • Contains data from both human and animal studies
  • Explains the linearized multi-stage mathematical model widely used by the US EPA for characterizing


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