Biomedical Science


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The Toxicologist's Pocket Handbook, Third Edition

Michael J. Derelanko
October 30, 2017

This scaled-down version of the best-selling CRC Handbook of Toxicology provides the most frequently used toxicology reference information in a convenient pocket-sized format allowing quick access to vital information, especially when traveling outside the lab or office....

Toxicologic Pathology: Nonclinical Safety Assessment

Pritam S. Sahota, James A. Popp, Jerry F. Hardisty, Chirukandath Gopinath
October 23, 2017

As drug development shifts over time to address unmet medical needs and more targeted therapies are developed, previously unseen pharmacological or off-target effects may occur in treatment. Designed to provide practical information for the bench toxicologic pathologist working in pharmaceutical...

The Clinical Chemistry of Laboratory Animals, Third Edition

David M. Kurtz, Gregory S. Travlos
October 19, 2017

Extensively updated and expanded since the publication of Walter F. Loeb and Fred W. Quimby’s second edition in 1999, the new The Clinical Chemistry of Laboratory Animals, Third Edition continues as the most comprehensive reference on in vivo animal studies. By organizing the book into species- and...

The Laboratory Nonhuman Primate, Second Edition

Jeffrey D. Fortman, Terry A. Hewett, Lisa C. Halliday
September 18, 2017

Extensively updated to include current literature, The Laboratory Nonhuman Primate, Second Edition, continues to serve as a quick reference source for technicians, caretakers, veterinarians, researchers, and students working with primates in biomedical research. It provides details on basic...

Endocrine Disruption Modeling

James Devillers
September 12, 2017

Uses Computational Tools to Simulate Endocrine Disruption Phenomena Endocrine Disruption Modeling provides a practical overview of the current approaches for modeling endocrine activity and the related potential adverse effects they may induce on environmental and human health. Based on the...

Lu's Basic Toxicology: Fundamentals, Target Organs, and Risk Assessment, Seventh Edition

Byung-Mu Lee, Sam Kacew, Hyung Sik Kim
September 01, 2017

Continuing a long tradition, Lu’s Basic Toxicology, Seventh Edition, combines relatively comprehensive coverage of toxic substances in food, air, and water with brevity, thereby continuing to serve as an updated introductory text for toxicology students and for those involved in allied sciences...

Health Risk Assessment Dermal and Inhalation Exposure and Absorption of Toxicants

Rhoda G.M. Wang, James B. Knaak, Howard I. Maibach
August 29, 2017

Health Risk Assessment is a comprehensive reference focusing on dermal absorption, cholinesterase inhibition, adverse reproductive effects, and carcinogenicity. The book features contributions from over 40 top scientists and covers topics such as PBPK modeling, cytochrome P-450 metabolism in skin,...

Management of Animal Care and Use Programs in Research, Education, and Testing, Second Edition

Robert H. Weichbrod, Gail A. (Heidbrink) Thompson, John N. Norton
August 28, 2017

Biomedical research using animals requires administrators and managers who are knowledgeable and highly skilled. They must adapt to the complexity of rapidly-changing technologies, balance research goals with a thorough understanding of regulatory requirements and guidelines, and know how to work...

Nonclinical Drug Administration: Formulations, Routes and Regimens for Solving Drug Delivery Problems in Animal Model Systems

Shayne C. Gad, Charles B. Spainhour
August 15, 2017

The concept of the perfect medicine as a molecule that goes with high selectivity to the therapeutic target site, does what it needs to do, and is subsequently cleared from the body is especially relevant now. Much of the current costs and post-market safety concerns arise from the inability to...

Cellular and Molecular Toxicology and In Vitro Toxicology

Daniel Acosta
July 14, 2017

This work concentrates on cellular and molecular toxicity of selected well-known drugs or chemicals on the cardiovascular system. The primary objective is to provide a better understanding of the mechanisms by which xenobiotics are toxic to mammalian tissues and cells. The use of in vitro cellular...

Alcohol and the Gastrointestinal Tract

Victor R. Preedy
July 13, 2017

This book covers all aspects of gastrointestinal tract problems caused by alcohol misuse. Opening chapters discuss epidemiology and the metabolism of alcohol and the liver's role in that process. Alcohol and acetaldehyde dehydrogenases, free radicals, and endocrine changes are discussed in detail....

Alcohol Interactions with Drugs and Chemicals

Edward J. Calabrese
July 13, 2017

Alcohol Interactions with Drugs and Chemicals is a concise volume that identifies, documents, and assesses the capacity of alcohol to alter the toxicity of chemical pollutants and drugs in animal models and humans. The book systematically assesses interactions according to general chemical classes...