The molecular pathogenesis of microbial agents responsible for respiratory tract infections (RTIs) has been the focus of much research in recent years. The emphasis has been on developing new treatments such as novel antimicrobials and more effective vaccines. Significant attention has also been paid to improving molecular diagnostic methods to identify RTI-causing microbes, as well as understanding the host response to them.
The Microbe-Host Interface in Respiratory Tract Infections presents an overview of the current knowledge in this area. It provides us with the first coherent picture of emerging strategies for controlling the microbes responsible for RTIs. This comprehensive volume is divided into three sections: the first reviews topics of general interest; the second focuses on bacterial and atypical RTIs; while the final section covers viral RTIs. Each of the chapters is the work of two or more of the top scientists in the field writing about their own pioneering research. Various chapters comment on vaccines, antibiotics, and molecular diagnostic methods.
This cutting-edge work is essential reading for research microbiologists and other scientists involved in the investigation and treatment of RTIs.
Table of Contents
Relevance of Genetic Background in Respiratory Tract Infections, T.G. Kimman and B. Hoebee
The Hygiene Hypothesis: The Role of Microbes in the Prevention of Atopy and Atopic Disease, L.E.M. Niers, T.J. Steenhuis, and M.O. Hoekstra
Respiratory Infection in the Immunocompromised Host: Recognition and Treatment, A.R. Gennery and A.J. Cant
New Diagnostic Modalities In Respiratory Tract Disease, A. Van Belkum and H.G.M. Niesters
The Pathogenesis of Bacterial Respiratory Tract Infection and Bronchitis, J. Zweigner and E. Tuomanen
The Role of Atypical Agents in Respiratory Tract Disease, M. Fonseca-Aten, A.M. Rios and R.D. Hardy
Infections in Patients with Cystic Fibrosis: Effects of a Longer Survival, H.E. Elphick and R.L. Smyth
Antibiotic Treatment of Lower Respiratory Tract Infection, F. Ghaffar and O. Ramilo
Vaccines in the Prevention of Bacterial Respiratory Tract Infections in Children, R.H. Veenhoven and E.A.M. Sanders
Pathogenesis of Respiratory Syncytial Virus Bronchiolitis: Immunological Aspects , J. Heidema, J.L.L. Kimpen, and G.M. van Bleek
Viral Infections and Childhood Asthma, M.J.J. Ermers and L. Bont
Adenovirus, L.M. Haveman, M. Bierings and T.F.W. Wolfs
Rhinovirus: Is It Really a Relevant Pathogen? O. Ruuskanen and T. Hyypiä
"…comprehensive…well-written, valuable…provides a sound, scientific base of knowledge."
Clinical Infectious Diseases, 2005