Target Organ Toxicity, Volume I

1st Edition

Cohen

CRC Press
Published August 31, 1986
Reference - 240 Pages
ISBN 9780849357756 - CAT# 5775

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Summary

This two-volume set provides essential information on the general princi-ples of target organ toxicity. Pharmacokinetics, metabolic activation and key defense mechanisms, excretion, species variation, and tissue-specific biochemistry are explored comprehensively. These general principles are then illustrated using specific examples of toxicity to different target organs and systems. DNA modifi-cation and repair in tumor induction, and specificity in tumor initiation are also examined. Of primary interest to toxicologist, pharma-cologists, biochemists, and environmental toxicologists.

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