Endothelial Cell Plasticity in the Normal and Injured Central Nervous System

Esperanza Meléndez Herrera, Bryan V. Phillips-Farfán, Gabriel Gutiérrez Ospina

January 28, 2015 by CRC Press
Reference - 270 Pages - 18 Color & 4 B/W Illustrations
ISBN 9781466599215 - CAT# K20941


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  • Presents essential information for practitioners in diverse fields including neurologists, gerontologists, and oncologists
  • Addresses neurodegenerative diseases such as Parkinson’s and Alzheimer’s as well as epilepsy and spinal injury
  • Covers new areas of investigation into endothelial cell plasticity


This book highlights the importance of endothelial cells as key players in the functioning of the nervous system under both normal and pathological conditions. The book demonstrates that endothelial cells are an essential and dynamic cell population in the central nervous system, with multiple and complex roles, not only in the maintenance of homeostasis, but also in the regulation of important processes. These include neurogenesis, neural control of reproduction, aging, neurodegeneration, and tumor invasion. The book exhaustively reviews the newest findings in this exciting new area of investigation.