Life Science

Cell Biology

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Bioreactors for Stem Cell Expansion and Differentiation

1st Edition

Joaquim M.S. Cabral, Claudia Lobato da Silva
October 09, 2018

An international team of investigators presents thought-provoking reviews of bioreactors for stem cell expansion and differentiation and provides cutting-edge information on different bioreactor systems. The authors offer novel insights into bioreactor-based culture systems specific for tissue...

Glutathione

1st Edition

Leopold Flohe
October 08, 2018

This is the first serious attempt to synthesize all that became known of glutathione over the last three decades. The book contains an update of glutathione biosynthesis with special emphasis on its regulation in adaptive stress responses. Other chapters review glutathione transport systems and...

The Modulation of DNA Content: Endopolyploidy, Polyteny, Aneuploidy and Chromatin Diminution

1st Edition

T. Ryan Gregory, Jillian D. Bainard
September 26, 2018

This book reviews various ways DNA content is modulated in the cells of multicellular organisms. Although the processes of endopolyploidy, polyteny, aneuploidy, and chromatin diminution have been observed for well over a century, their biological significance has not been appreciated due to the...

Nucleosome Dynamics in Epigenetic Regulation

1st Edition

Cizhong Jiang, Min Li, Jiannan Lin
September 15, 2018

The topic of nucleosome dynamics is of exceptional current interest in a number of subfields of modern biology, including molecular biology, structural biology, cell biology, systems biology and biophysics. Changes in nucleosome structure are necessary to regulate DNA repair and for the regulation...

Signal Transduction and Smooth Muscle

1st Edition

Mohamed Trebak, Scott Earley
September 11, 2018

All hollow organs, such as blood vessels, the gastrointestinal tract, airways, male and female reproductive systems, and the urinary bladder are primarily composed of smooth muscle. Such organs regulate flow, propulsion and mixing of luminal contents and storage by the contraction and relaxation of...

The Human Microbiota in Health and Disease: An Ecological and Community-based Approach

1st Edition

Michael Wilson
September 10, 2018

A human being consists of a mammalian component and a multiplicity of microbes, collectively referred to as the "microbiota" or "microbiome," with which it has a symbiotic relationship. The microbiota is comprised of a variety of communities, the composition of each being dependent on the body site...

Chromosomal Nonhistone Protein: Volume II: Immunology

1st Edition

L. S. Hnilica
July 27, 2018

The second volume of the Chromosomal Nonhistone Proteins treatise is dedicated in its entirety to the immunobiology of these proteins. Since immunological methods are adding rapidly to our knowledge of the specificity and intranuclear localization of chromosomal nonhistone proteins, a collection of...

A Probabilistic Model of the Genotype/Phenotype Relationship: Does Life Play the Dice?

1st Edition

Jean-Pierre Hugot
July 24, 2018

A Probabilistic Model of the Genotype/Phenotype Relationship provides a new hypothesis on the relationship between genotype and phenotype. The main idea of the book is that this relationship is probabilistic, in other words, the genotype does not fully explain the phenotype. This idea is developed...

Chromosomal Nonhistone Protein: Volume I: Biology

1st Edition

L. S. Hnilica
June 28, 2018

The first volume of the Chromosomal Nonhistone Proteins treatise presents a summary of the many attempts in the literature to correlate changes in chromosomal histone proteins specificity and metabolism with transcriptional regulations in eukaryotic cells....

Chromosomal Nonhistone Protein: Volume III: Biochemistry

1st Edition

L. S. Hnilica
June 28, 2018

The third volume of the Chromosomal Nonhistone Proteins treatise deals with the isolation and analysis of chromosomal proteins in general with specific features of these proteins in particular. In addition to the high mobility group (HMG) proteins, post synthetic modifications of chromosomal...

Chromosomal Nonhistone Protein: Volume IV: Structural Associations

1st Edition

L. S. Hnilica
June 28, 2018

The fourth and last volume of Chromosomal Nonhistone Proteins sequence attempts to confront these macromolecules with the major structural elements of the cell nucleus (with the exception of nucleosomes which will be treated separately in a later treatise). Proteins of the chromosomes, nucleoli,...

Cells in Evolutionary Biology: Translating Genotypes into Phenotypes - Past, Present, Future

1st Edition

Brian K. Hall, Sally A. Moody
June 12, 2018

This book is the first in a projected series on Evolutionary Cell Biology, the intent of which is to demonstrate the essential role of cellular mechanisms in transforming the genotype into the phenotype by transforming gene activity into evolutionary change in morphology. This book —Cells in...

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