Cancer-Causing Viruses and Their Inhibitors

1st Edition

Satya Prakash Gupta

CRC Press
Published May 16, 2014
Reference - 511 Pages - 21 Color & 85 B/W Illustrations
ISBN 9781466589773 - CAT# K20424

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Summary

Cancer-causing viruses, also called oncoviruses, play a key role in the development of certain cancers. They contribute to genetic changes that disrupt the cell cycle machinery, interfering with functions such as cell growth. Cancer-Causing Viruses and Their Inhibitors presents a plethora of research from internationally reputed contributors who discuss different types of oncoviruses, their mechanisms of invasion and growth, and their life cycles.

The book begins with an overview of the oncoviruses discovered to date and includes a brief description of their structures, genotypes, replication, and mechanisms of infection leading to cancers. It then explores several of these viruses in detail, including:

  • Human T-cell leukemia virus type 1 (HTLV-1)
  • Hepatitis C virus (HCV)
  • Epstein–Barr virus (EBV)
  • Human papilloma virus (HPV)
  • Human herpes virus 8 (HHV-8)/Kaposi’s sarcoma-associated herpes virus (KSHV)
  • Human immunodeficiency virus (HIV/AIDS)
  • Oncolytic viruses

This book is an essential reference for those working in virology, oncology, and biotechnology. The discoveries presented will enable researchers and clinicians to optimize both historical and current approaches to anti-viral therapies.