The book opens with chapters that focus on the development of molecular diagnostic tools and these are followed by chapters on genetic evolution and its relationship to pathogenicity. Other topics include Brucella comparative genomics and proteomics, analysis of the structure, biosynthesis and biology of glucans and lipopolysaccharides, pathogenicity, approaches to vaccine development, bacterium-host interactions, immune response, and much more. Essential reading for everyone with an interest in Brucella and brucellosis and recommended reading for the wider body of scientists with an interest in microbial diagnostics, microbial pathogenesis, cellular microbiology and immunology, and vaccine development.
Biography
Ignacio Lopez-Goni, Ignacio Moriyon
The breadth of topics covered in this book make it a useful introduction or update for those intending to study this 'stealthy' pathogen, and also to those with a more general interest in intracellular bacterial pathogenesis. - Nicky Commander, VLA Weybridge, Microbiology Today
This is a very useful volume for anyone interested in developments in brucellosis research. - Clinical Infectious Disease, 2006:42 (1 February)