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In this unique book, experts describe practices applicable to the large-scale processing of biotechnological products. Beginning with processing and bulk storage preservation techniques, the book provides strategies for improving efficiency of process campaigns of multiple products and manufacturing facilities for such processing techniques. Large-scale chromatography for the purification of biomolecules in manufacturing and lyophilization of protein pharmaceuticals are discussed. Includes a case study on blow-fill-seal processing technology and a chapter on economic and cost factors for bioprocess engineering.
Table of Contents
Chapters cover: o Large-Scale Freezing & Thawing of Biopharmaceutical Products, R. Wisniewski & V. Wu o Process Design for Large-Scale Chromatography of Biomolecules, R. Wisniewski, E. Boschetti, & A. Jungbauer o Lyophilization of Protein Pharmaceuticals, J. Carpenter & B. Chang o Blow-Fill-Seal Technology: A Case Study, V. Wu & F. Leo o Multiproduct Facility Design, T. Hughes o Economic & Cost Factors of Bioprocess Engineering, S. Wheelwright
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CHOICE – Outstanding Academic Title – Award Winner
CHOICE – 2018 Outstanding Academic Title – Award Winner
Shingo Research and Professional Publication Award Winner
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