Pharmaceutical Science

Biotechnology/Biopharmaceuticals

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Sedimentation Velocity Analytical Ultracentrifugation: Interacting Systems

Peter Schuck, Huaying Zhao
October 04, 2017

Analytical ultracentrifugation is one of the most powerful solution techniques for the study of macromolecular interactions, to define the number and stoichiometry of complexes formed, and to measure affinities ranging from very strong to very weak and repulsive. Building on the data analysis...

Biosimilars and Interchangeable Biologics: Strategic Elements

Sarfaraz K. Niazi
September 30, 2017

What’s the Deal with Biosimilars? Biosimilars are gaining momentum as new protein therapeutic candidates that can help fill a vital need in the healthcare industry. The biological drugs are produced by recombinant DNA technology that allows for large-scale production and an overall reduction time...

RNA Nanotechnology and Therapeutics

Peixuan Guo, Farzin Haque
September 30, 2017

Interest in RNA nanotechnology has increased in recent years as recognition of its potential for applications in nanomedicine has grown. Edited by the world's foremost experts in nanomedicine, this comprehensive, state-of-the-art reference details the latest research developments and challenges in...

Carrier-Mediated Dermal Delivery: Applications in the Prevention and Treatment of Skin Disorders

Andreia Ascenso, Helena Ribeiro, Sandra Simões
August 18, 2017

This book presents new approaches for skin aging and photocarcinogenesis and topical formulations based on nanocarrier systems for skin disorders. It discusses cosmeceuticals, laser, photodynamic therapy, and melatonin-based treatments as important strategies for photoaging management. Photodynamic...

In Silico Drug Discovery and Design: Theory, Methods, Challenges, and Applications

Claudio N. Cavasotto
July 26, 2017

In Silico Drug Discovery and Design: Theory, Methods, Challenges, and Applications provides a comprehensive, unified, and in-depth overview of the current methodological strategies in computer-aided drug discovery and design. Its main aims are to introduce the theoretical framework and algorithms,...

Delivery Strategies for Antisense Oligonucleotide Therapeutics

Saghir Akhtar
July 13, 2017

With contributions from leading experts, this book is the first to focus solely on addressing the problems and reviewing the strategies currently being used to improve the delivery of antisense nucleic acids. Important delivery issues, such as improving biological stability, improving cell-specific...

Industrial Applications of Marine Biopolymers

Parappurath Narayanan Sudha
June 27, 2017

Industrial Applications of Marine Biopolymers presents different classes of marine biopolymers and their industrial applications, demonstrating the precious value of ocean resources to society. This timely volume discusses the exceedingly useful polymers derived from these materials that are...

Biodrug Delivery Systems: Fundamentals, Applications and Clinical Development

Mariko Morishita, Kinam Park
June 16, 2017

Biodrug Delivery Systems: Fundamentals, Applications and Clinical Development presents the work of an international group of leading experts in drug development and biopharmaceutical science who discuss the latest advances in biodrug delivery systems and associated techniques. The book discusses...

3D Cell-Based Biosensors in Drug Discovery Programs: Microtissue Engineering for High Throughput Screening

William S. Kisaalita
June 13, 2017

Advances in genomics and combinatorial chemistry during the past two decades inspired innovative technologies and changes in the discovery and pre-clinical development paradigm with the goal of accelerating the process of bringing therapeutic drugs to market. Written by William Kisaalita, one of...

Approaches to the Conformational Analysis of Biopharmaceuticals

Roger L. Lundblad
May 31, 2017

The activity of many biopharmaceutical polymers is dependent on conformation, and the next several years will see increased interest in the conformational analysis of these polymers resulting from the development of biosimilar or "follow-on" biological products. While a wide variety of approaches...

Biopharmaceuticals in Plants: Toward the Next Century of Medicine

Kathleen Laura Hefferon
May 22, 2017

Transgenic plants present enormous potential to become one of the most cost-effective and safe systems for large-scale production of proteins for industrial, pharmaceutical, veterinary, and agricultural uses. Over the past decade, much progress has been made with respect to the development of...

Fundamentals of Biofilm Research, Second Edition

Zbigniew Lewandowski, Haluk Beyenal
March 31, 2017

The six years that have passed since the publication of the first edition have brought significant advances in both biofilm research and biofilm engineering, which have matured to the extent that biofilm-based technologies are now being designed and implemented. As a result, many chapters have been...

Conferences

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