Cardiac Regeneration using Stem Cells

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ISBN 9781466578395
Cat# K16833

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ISBN 9781466578401
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Features

  • Presents the current status and a future perspective of cardiac regeneration using pluripotent stem cells
  • Examines iPS cell generation methods, cardiomyocyte differentiation protocols, cardiomyocyte characterization methods, and tissue engineering
  • Discusses how to purify cardiomyocytes for research and therapeutic purposes
  • Reviews cardiac cell therapy for ischemic heart disease
  • Explores in vitro generation of efficacious platelets from iPS cells as well as neuron regeneration

Summary

To achieve cardiac regeneration using pluripotent stem (iPS) cells, researchers must understand iPS cell generation methods, cardiomyocyte differentiation protocols, cardiomyocyte characterization methods, and tissue engineering. This book presents the current status and future possibilities in cardiac regeneration using iPS cells. Written by top researchers who present new data in these fields, this book reviews cardiac cell therapy for ischemic heart disease and explores in vitro generation of efficacious platelets from iPS cells. It also discusses modeling arrhythmogenic heart disease with patient-specific induced pluripotent stem cells.

Table of Contents

Induced Pluripotent Stem Cells
Yoshinori Yoshida and Shinya Yamanaka

Human iPS cell generation methods for clinical usage
Tomohisa Seki and Shinsuke Yuasa

Reprogramming and Regenerative medicine: Unique approach via protein-derived iPS
Hyun-Jai Cho, Yoo-Wook Kwon, and Hyo-Soo Kim

Lessons from Heart Development to Regeneration
Hiroyuki Yamagishi.

Directed and Systematic Differentiation of Cardiovascular Cells from Mouse and Human Pluripotent Stem Cells
Hideki Uosaki and Jun K. Yamashita1

Wnt Signaling in Cardiogenesis
Atsuhiko T. Naito, Seitaro Nomura, Ichiro Shiojima, and Issei Komuro

The control of proliferation of pluripotent stem cell-derived cardiomyocyte
Shinsuke Yuasa

How to purify cardiomyocytes for research and therapeutic purposes
Fumiyuki Hattori

Ion channel expression and function of iPSC-derived cardiomyocytes
Tetsushi Furukawa

Pharmacology and Future Application of iPS Cell-derived Cardiomyocytes
Mitsushige Murata

Cardiac Regeneration Using Isl1-positive Cardiac Progenitor Cells
Yasuhiro Nakashima

Cell Sheet Engineering for Heart Tissue Repair
Katsuhisa Matsuura and Tatsuya Shimizu

Construction of functional cardiovascular tissues using magnetic nanoparticles
Jong-Kook Lee, Akira Ito, and Hiroyuki Honda

Cardiac cell therapy for ischemic heart disease
Hideaki Kanazawa, Konstantinos Malliaras, Michelle Kreke, and Eduardo Marbán

Induced Cardiomyocytes: Direct Reprogramming for Cardiac Regeneration
Masaki Ieda

Modeling Arrhythmogenic Heart Disease with Patient-Specific Induced Pluripotent Stem Cells
Daniel Sinnecker, Alexander Goedel, Ralf J. Dirschinger, Alessandra Moretti, and Karl-Ludwig Laugwitz

In Vitro Generation of Efficacious Platelets from iPS Cells
Naoya Takayama and Koji Eto

Neuron Regeneration Using iPS Cells
Satoshi Nori, Osahiko Tsuji, Kyoko Miura, Yoshiaki Toyama, Masaya Nakamura, and Hideyuki Okano