Biomaterials for Stem Cell Therapy

Biomaterials for Stem Cell Therapy: State of Art and Vision for the Future

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Features

  • Takes a practical look at stem cell applications
  • Explores current thinking on how to use new technologies in biomaterials for disease treatment
  • Includes contributions from top researchers
  • Discusses recent advances in stem cell biology, biomaterials, and technological approaches such as bioreactors
  • Covers applications such as nerve regeneration, bone repair, and cardiovascular therapy

Summary

Focused on stem cell applications, this book bridges the fields of biomaterials, offering new insights into constructing and regenerating tissues and organs. Its unique feature is linking diseases of the human body to current thinking on how to deal with them in the context of current concepts and technologies by means of an in-depth focus on biomaterials. The book assembles recent advances and covers a range of topics related to stem cell biology, biomaterials and technological approaches such as bioreactors written by top researchers in the field. Stem cells of both embryonic and adult origin are discussed with applications ranging, but not limited to, nerve regeneration, liver, pancreas, skin, trachea, cartilage and bone repair and cardiovascular therapy. Developments in the field reflecting the design and construction of the human body and its principal anatomy are discussed from a materials point of view.

The book will be a valuable tool for biomaterial scientists, tissue engineers, clinicians as well as stem cell biologists involved in basic research and applications of adult and embryonic stem cells. It will also be a source of reference for students in biotechnology, biomedical engineering, biology, biochemistry, materials sciences, pharmaceuticals, and veterinary and human medicine.

Table of Contents

Innovative Biomaterials
Synthetic Polymer-Network Based Materials in Stem Cell Research
Adam L. Sisson and Andreas Lendlein

Membrane Systems in Liver Regenerative Medicine
Simona Salerno, Loredana De Bartolo, and Enrico Drioli

Blood-derived biomaterials: what role can they play in regenerative medicine and stem cell therapy ?
Chen-Yao Su and Thierry Burnouf

Pectins as Future Biomaterials
Hanna Kokkonen and Juha Tuukkanen

Biointerfaces between Biomaterials and Biosystems in Tissue Engineering: Potential Contributions of Two-Photon Polymerization and Polyelectrolyte Multilayer Coatings
S. Grohmann, T.Weiß, and K. Liefeith

Cell-Material Interactions
Sabrina Morelli and Antonella Piscioneri

Stem Cells
Bone Marrow Stem Cells
Xuetao Pei, Wen Yue, Junnian Zhou, Xinlong Yan, Jingxue Wang, Jiafei Xi, Haiyun Pei, and Hailei Yao

Umbilical Cord Matrix Cells–Promising Instrument For Regenerative Medicine
Maslova O.O., Deryabina O.G., and Kordium V.A.

Cellular Properties of Mesenchymal Cells Derived from the Decidua of Human Term Placenta and Their Applications in Regenerative Medicine
Daisuke Kanematsu and Yonehiro Kanemura

Adipose Tissue: a New Source of Hepatic Cells.
Ana Bonora-Centelles, Ramiro Jover Atienza, Vicente Mirabet Lis, José Vicente Castell Ripoll, and MªJosé Gómez-Lechón

Engineering Biomimetic Microenvironments Using Biomaterials, Soluble Signals for Ex Vivo Expansion and Differentiation of Stem Cells: Strategic Challenges For Creation of Clinical Grades for Stem Cell Therapy
Shibashish Giri and Augustinus Bader

Translational Strategies
Bioartificial Pancreas
Yuji Teramura and Hiroo Iwata

Trachea and Larynx in Regenerative Medicine
Silvia Baiguera, M. Jaus, A. Gonfiotti, and Paolo Macchiarini

Organ Printing: a Novel Tissue Engineering Paradigm
Francoise Marga, Karoly Jakab, IoanKosztin, and Gabor Forgacs

Stem Cell Microencapsulation for Therapeutic Angiogenesis
Clara Sanz Nogués, Dilip Thomas, Abhay Pandit, and Timothy O’Brien

Microencapsulation and Bioreactors for Liver Support
Murielle Dufresne, Nhu Mai Tran, Stéphanie Capone, Martine Daujat, and Cecile Legallais

Mass Transfer and Computational Fluid-Dynamics in Bioreactors
Efrem Curcio and Loredana De Bartolo

Innovative Solutions for Wound Therapy
Christina Irene Günter and Hans-Günther Machens

Neuroprotection and Neuroregeneration Strategies for Neurodegenerative Diseases
Frank Striggow

Membrane Emulsification for Cell Delivery
Emma Piacentini, Enrico Drioli, and Lidietta Giorno

Regulations and Ethical Issues
GMP Requirements and Quality Management of Cellular Products
Markus Neubauer and Saskia Knothe

From Laboratory Bench to Registration and Marketing Approval: Clinical Development for the Biomaterial Developer
Rita Dobmeyer

The Tension between Conflicting Fundamental Values: The Ethical Challenge of Embryonic Stem Cell Research
Eckhard Nagel

 
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