Anthocyanins in Health and Disease

Taylor C. Wallace, M. Monica Giusti

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September 4, 2013 by CRC Press
Professional - 368 Pages - 60 B/W Illustrations
ISBN 9781439894712 - CAT# K14214

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Features

  • Presents the first comprehensive review of the relationship of anthocyanins to human health and disease
  • Offers technical content provided by expert authors
  • Describes how the chemical structure of anthocyanins enables them to modulate inflammatory pathways, preventing the development of chronic disease
  • Provides an authoritative resource for researchers, with potential impact on the development of food and supplement products containing anthocyanins
  • Stimulates and helps focus readers’ in future research efforts towards the prevention of chronic disease
  • Discusses the role of anthocyanins in the cardiovascular system, their anti-cancer activities, and positive effects on cognition in animal and human models
  • Describes anthocyanins' potential health benefits in eye disease, particularly macular degeneration
  • Covers anthocyanins' use as color additives/extracts from natural sources and stability in foods as value-added functional ingredients

Summary

Anthocyanins, polyphenolic compounds abundant in certain foods, are responsible for the orange-red to blue-violet hues evident in many fruits, vegetables, cereal grains, and flowers. Interest in these pigments has intensified due to their potential health-promoting properties as dietary antioxidants, as well as their use as natural dyes in a variety of products. Mechanistic studies from in vitro experiments as well as in vivo clinical trials demonstrate wide-ranging efficacy and biological activity of anthocyanins. Anthocyanins in Health and Disease presents the first comprehensive review of modern-day research on the relationship of anthocyanins to human health and disease.

Written by an interdisciplinary group of distinguished scientists, this book examines the bioavailability, chemistry, metabolism, and efficacy of anthocyanins, as well as their role in protecting the body from several age- and obesity-related chronic diseases. Chapters cover the absorption, digestion, metabolism, and excretion of anthocyanins; current methodology for the assessment of anthocyanins in the blood, plasma, urine, and tissues; and anthocyanins as potent antioxidants.

The book discusses health-related topics such as anthocyanins and protection against disease, including cardiovascular disease, metabolic syndrome, type-2 diabetes, and cancers of the gastrointestinal tract. It also addresses health-promoting effects of anthocyanins, namely, maintenance of normal vision and prevention of ocular pathologies, protective effects against skin aging, and their role in innate immunity and exercise. Covering a wide array of specialized knowledge, this book provides an authoritative source of information on the role of anthocyanins in health and disease, an important step toward advancing research and enhancing communication on these functional ingredients.