Physics of Mammographic Imaging

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ISBN 9781439875445
Cat# K13500



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Cat# KE13643



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  • Provides a comprehensive, detailed, and state-of-the-art overview of the technical aspects of mammographic imaging and its clinical context
  • Covers fundamental issues of image formation, including the basics of digital mammography, contrast enhancement, stereomammography, breast tomosynthesis, and breast computed tomography
  • Gives detailed treatment of image interpretation with topics that range from breast cancer detection and diagnosis and image-guided procedures to image display and image perception
  • Discusses image analysis and modeling issues (physical phantoms, digital phantoms, observer models, and computer-aided detection) as well as complementary approaches such as multimodality imaging, ultrasound imaging of the breast, breast MRI, and nuclear imaging of the breast
  • Concludes with a section that deals with emerging areas of breast elastography, electrical impedance imaging, optical imaging of the breast, and computer-based decision support in breast cancer care


Due to the increasing number of digital mammograms and the advent of new kinds of three-dimensional x-ray and other forms of medical imaging, mammography is undergoing a dramatic change. To meet their responsibilities, medical physicists must constantly renew their knowledge of advances in medical imaging or radiation therapy, and must be prepared to function at the intersection of these two fields. Physics of Mammographic Imaging gives an overview on the current role and future potential of new alternatives to mammography in the context of clinical need, complementary approaches, and ongoing research.

This book provides comprehensive coverage on the fundamentals of image formation, image interpretation, analysis, and modeling. It discusses the use of mammographic imaging in the detection, diagnosis, treatment planning, and monitoring of breast cancer. Expert authors give a balanced summary of core topics such as digital mammography, contrast-enhanced mammography, stereomammography, breast tomosynthesis, and breast CT. The book highlights the use of mammographic imaging with complementary breast imaging modalities such as ultrasound, MRI, and nuclear medicine techniques. It discusses critical issues such as computer-aided diagnosis, perception, and quality assurance.

This is an exciting time in the development of medical imaging, with many new technologies poised to make a substantial impact on breast cancer care. This book will help researchers and students get up to speed on crucial developments and contribute to future advances in the field.

Table of Contents

Image Formation
Fundamentals of Digital Mammography
Xin Qian
Contrast-Enhanced Digital Mammography
Melissa L. Hill and Martin J. Yaffe
Stereo Mammography
David J. Getty
Breast Tomosynthesis
Ying (Ada) Chen
Breast CT
Chris C. Shaw and Gary J. Whitman
Comparison of Advanced X-Ray Modalities
Ying (Ada) Chen, David J. Getty, Melissa L. Hill, Mia K. Markey, Xin Qian, Chris C. Shaw, Gary J. Whitman, and Martin J. Yaffe

Image Interpretation
Breast Cancer Detection and Diagnosis
Margaret Adejolu and Gary J. Whitman
Image-Guided Procedures and Surgical Planning
Nehmat Houssami, Robin Wilson, and Jennifer Rusby
Displays for Breast Imaging
Aldo Badano
Perception of Mammographic Images
Elizabeth Krupinski

Image Analysis and Modeling
Physical Breast Phantoms
Ernest L. Madsen
Digital Phantoms for Breast Imaging
Predrag R. Bakic and Andrew D.A. Maidment
Observer Models for Breast Imaging
François Bochud
Current Status of Computer-Aided Detection of Breast Cancer
Huong (Carisa) Le-Petross and Tanya W. Stephen

Complementary Approaches
Breast Ultrasound
Gary J. Whitman, Raunak Khisty, and R. Jason Staffor
Breast MRI
Deanna L. Lane, R. Jason Stafford, and Gary J. Whitman
Nuclear Medicine Imaging of the Breast: History, Clinical Application and Integration, and Future
Rachel F. Brem, Caitrín Coffey, Jessica Torrente, and Jocelyn Rapelyea

Future Directions
Breast Elasticity Imaging
Salavat Aglyamov, Richard Bouchard, Iulia Graf, and Stanislav Emelianov
Electrical Impedance Imaging and Spectroscopy of the Breast
Bin Zheng and Lihua Li
Optical Imaging of the Breast
Kelly E. Michaelsen, Michael A. Mastanduno, Ashley M. Laughney, Brian W. Pogue, and Keith D. Paulsen
Outlook for Computer-Based Decision Support in Breast Cancer Care
Gautam S. Muralidhar, Alan C. Bovik, and Mia K. Markey

Author Bio(s)

Editorial Reviews

"This is a much-needed and refreshing update on the state-of-the art of the technological aspects of breast imaging. This book captures a snapshot of the current status of the technology and practice in this field. It is well organized and the chapters make generous use of informative figures, tables, and medical images. The authors present well-balanced views based on their own research experience and on the existing body of knowledge in this field. The editor and authors have accomplished their objective in delivering an excellent book on this topic. It is a must have for anyone working or interested in the physics and technological aspects of mammographic imaging."
—Andrew Karellas, PhD, University of Massachusetts Medical School, Worcester, USA