Thyroid Cancer: From Emergent Biotechnologies to Clinical Practice Guidelines
Features
- Vision of biotechnologies that are realistically going to impact the care of thyroid cancer patients
- Description of molecular medicine in thyroid cancer by the actual researchers conducting the pivotal studies in the field
- Comprehensive organization of material covering all aspects of thyroid cancer management for the present time and near future
- Extensive inclusion of figures and images describing cutting edge technologies
- Synthesis of emergent biotechnologies into a practical approach that may be reflected in forthcoming clinical practice guidelines
Summary
The current age of clinical medicine is witnessing biotechnological innovation at an unprecedented pace. As a result, the recently popularized clinical practice guidelines (CPG), as a tool to assist clinical decision-making, have been struggling to keep up. Thyroid Cancer: From Emergent Biotechnology to Clinical Practice Guidelines rides the wave of medical innovation, analyzing current and future CPG, and providing an up-to-date and comprehensive treatise on thyroid cancer, its diagnosis, and treatment.
A synthesis of ideas by prominent world experts in the field of thyroid cancer research and clinical practice, Thyroid Cancer covers:
- Technologically-advanced diagnostic procedures and therapeutic interventions
- Diagnostic techniques employed in the detection and follow-up of thyroid cancer including ultrasound, needle aspiration techniques, CT, PET, PET-CT, and MRI
- Basic principles of systems biology, molecular and translational medicine, CPG development, and risk stratification for thyroid cancer
- How CPG contain knowledge gaps and produce uncertainty
- Advances in the field, including new surgical techniques, molecular targeted therapies, external beam radiation therapy, and chemotherapy
A comprehensive, scientific description of current and future diagnostic and therapeutic modalities for the management of thyroid cancer, this treatise is an indispensible reference for both the specialist and referring physician.
Table of Contents
Principles of Translational Medicine and Applications to Thyroid Cancer Investigation
Emily Jane Gallagher and Derek LeRoith
Systems Biology—An Overview
Ravi Iyengar and Azi Lipshtat
Genetic and Epigenetic Alterations in the MAP Kinase and PI3K/Akt Pathways in Thyroid Cancer
Mingzhao Xing and Paul W. Ladenson
Genetic and Molecular Pathophysiology of Medullary Thyroid Carcinoma
Rosa Maria Paragliola, Salvatore M. Corsello, Francesco Torino, and Agnese Barnabei
Risk Stratification in Differentiated Thyroid Cancer
Giuseppe Barbesino
Clinical Practice Guidelines for Thyroid Cancer: Where Are We Now?
Jeffrey I. Mechanick
Illustrative Case Studies of Thyroid Carcinoma and the Emerging Role of Molecular Medicine
Donald Bergman and Rhoda H. Cobin
Advances in Thyroid Ultrasound for Detection and Follow-Up of Thyroid Malignancies: Technical and Clinical Aspects
Laurence Leenhardt, François Tranquart, and Jean Tramalloni
Multimodality Imaging and Aspiration Biopsy Guidance in the Perioperative Management of Thyroid Carcinoma
Jing Gao, Jonathan K. Kazam, and Elias Kazam
The Use of Diagnostic Radiotracers in Thyroid Cancer
Josef Machac
PET-CT Scanning in the Management of Thyroid Cancer: Experience with a Cohort of 100 Patients
Dario Casara, Faise Al Bunni, Maria Rosa Pelizzo, and Fabio Pomerri
The Emerging Role of Percutaneous Needle Biopsy and Molecular Tumor Marker Analysis for the Preoperative Selection of Thyroid Nodules
Angelo Carpi, Jeffrey I. Mechanick, and Andrea Nicolini
Image-Guided Mini-Invasive Ablation of Thyroid Tumors and Distant Metastases
Enrico Papini, Antonio Bianchini, Rinaldo Guglielmi, Claudio M. Pacella,Irene Misischi, Laura Papini, and Giancarlo Bizzarri
Thyroidectomy and Neck Exploration: New Surgical Approaches
Jean-Christophe Lifante and William B. Inabnet III
Thyroid Surgery Performed under Local Anesthesia and Same-Day Surgery
Joseph DiNorcia and John D. Allendorf
The Use of Therapeutic Radiotracers in Thyroid Cancer
Josef Machac
External Beam Radiation Therapy in Thyroid Cancer
Walter Choi and Louis Harrison
Role of Chemotherapy in Thyroid Cancer
Paolo Bossi and Laura D. Locati
Role of NF-κB in Thyroid Cancer
Eriko Suzuki, Shunichi Yamashita, and Kazuo Umezawa
Biologically Targeted Therapies for Thyroid Cancers
Steven I. Sherman
Molecular Targeted Therapies of Medullary Thyroid Carcinoma
Francesco Torino, Agnese Barnabei, Rosa Maria Paragliola, and Salvatore M. Corsello
Synthesis of Emergent Biotechnologies into Future CPG
Jeffrey I. Mechanick, Angelo Carpi, Mark Urken, Donald Bergman, and Rhoda H. Cobin
Author Bio(s)
Angelo Carpi, MD is a clinical researcher at the University Hospital of Pisa. He is also an associate professor of Internal Medicine at Pisa University.
Jeffrey I. Mechanick, MD, Mount Sinai School of Medicine, New York City, is a Clinical Professor within the Department of Medicine, Division of Endocrinology, Diabetes, and Bone Disease at the Mount Sinai School of Medicine.
