Comprehensive Brachytherapy

Comprehensive Brachytherapy: Physical and Clinical Aspects

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Features

  • Provides essential background information and practical guidelines for quick reference
  • Offers a balanced perspective from experts across the globe
  • Includes recommendations from the major professional organizations
  • Integrates the physics and clinical aspects of the practice
  • Presents a complete overview of the design, performance, and management of quality assurance programs
  • Discusses research areas and provides a view on future developments

Summary

Modern brachytherapy is one of the most important oncological treatment modalities requiring an integrated approach that utilizes new technologies, advanced clinical imaging facilities, and a thorough understanding of the radiobiological effects on different tissues, the principles of physics, dosimetry techniques and protocols, and clinical expertise. A complete overview of the field, Comprehensive Brachytherapy: Physical and Clinical Aspects is a landmark publication, presenting a detailed account of the underlying physics, design, and implementation of the techniques, along with practical guidance for practitioners.

Bridging the gap between research and application, this single source brings together the technological basis, radiation dosimetry, quality assurance, and fundamentals of brachytherapy. In addition, it presents discussion of the most recent clinical practice in brachytherapy including prostate, gynecology, breast, and other clinical treatment sites. Along with exploring new clinical protocols, it discusses major advances in imaging, robotics, dosimetry, Monte Carlo-based dose calculation, and optimization.

Table of Contents

Introduction
Introduction and Innovations in Brachytherapy
Jack Venselaar, Dimos Baltas, Peter Hoskin, and Ali S. Meigooni
Standard Technology in Brachytherapy
Rupak Das and Jack Venselaar
Radionuclides in Brachytherapy: Current and Potential New Sources
Facundo Ballester, Ravinder Nath, and Dimos Baltas
Quality Assurance of Equipment
Jack Venselaar and Firas Mourtada

Brachytherapy Dosimetry
Source Calibration
Hans Bjerke, Larry DeWerd, Jan Seuntjens, and Margaret Bidmead
Experimental Dosimetry Methods
Dimos Baltas, Brigitte Reniers, and Ali S. Meigooni
Computational Methods for Dosimetric Characterization of Brachytherapy Sources
Panagiotis Papagiannis, Luc Beaulieu, and Firas Mourtada

Brachytherapy Treatment Planning and Imaging
Historical Development of Predictive Dosimetry "Systems"
Ali S. eigooni, Margaret Bidmead, and Jack Venselaar
Two-, Three-, and Four-Dimensional Brachytherapy
Jean Pouliot, Ron Sloboda, and Brigitte Reniers
TG-Dose Calculation Formalism: Development, Insights, and Modernization
Mark Rivard, Ali Soleimani-Meigooni, and Ravinder Nath
On the Introduction of Model-Based Algorithms Performing Nonwater Heterogeneity Corrections into Brachytherapy Treatment Planning
Åsa Carlsson Tedgren, Frank Verhaegen, and Luc Beaulieu
Optimization and Evaluation
Dimos Baltas and Inger-Karine Kolkman-Deurloo
Quality Management of Treatment Planning
Ali S. Meigooni, and Jack Venselaar
Practical Use, Limitations, and Quality Control of Imaging in Brachytherapy
Frank-André Siebert and Taran Paulsen Hellebust

Uncertainties in Clinical Brachytherapy
Uncertainties Associated with Brachytherapy Source Calibrations and Dose Calculations
Larry DeWerd, Mark Rivard, and Hans-Joachim Selbach
Uncertainties Associated with Clinical Aspects of Brachytherapy
Peter Hoskin, Alfredo Polo, and Jack Venselaar
Margin Concepts in Image-Guided Brachytherapy
Kari Tanderup, Christian Kirisits, Jacob Lindegaard, Erik van Limbergen, André Wambersie, and Richard Pötter

Clinical Brachytherapy
Clinical Use of Brachytherapy
Peter Hoskin
Radiobiology for Brachytherapy
David Carlson, Zhe Chen, Peter Hoskin, Zoubir Ouhib, and Marco Zaider
Brachytherapy for Prostate Cancer
Alfredo Polo and Michel Ghilezan
Brachytherapy for Gynecologic Cancers
Beth Erickson, Mahesh Kudrimoti, and Christine Haie-Meder
Brachytherapy for Breast Cancer
Kara Lynne Leonard and Erik Van Limbergen
Brachytherapy for Other Treatment Sites
Vratislav Strnad, Beth Erickson, and Mahesh Kudrimoti

Developments in Clinical Brachytherapy
Developments in Gynecologic Brachytherapy Dose Recording and Reporting: From ICRU Report to Image-Guided Brachytherapy
John Mignano
In Vivo Dosimetry in Brachytherapy
Joanna Cygler, Kari Tanderup, Sam Beddar, and José Pérez-Calatayud
Special Brachytherapy Modalities
Christopher Melhus, Mark Rivard, and Ravinder Nath
Advanced Brachytherapy Technologies: Encapsulation, Ultrasound, and Robotics
Mark Rivard, Luc Beaulieu, and Marinus Moerland
Intraoperative Brachytherapy
Joost Jan Nuyttens and Subir Nag

Radiation Protection and Quality Management in Brachytherapy
Radiation Protection in Brachytherapy
Panagiotis Papagiannis and Ning Yue
New Paradigm for Quality Management in Brachytherapy
Susan Richardson, Geethpriya Palaniswaamy, Sasa Mutic, and Eric Klein
Quality Audits in Brachytherapy
Carlos de Almeida, David Followill, and Claudio Sibata
Expert Training in Brachytherapy
Alex Rijnders, Zoubir Ouhib, György Kovács, and Peter Grimm

Editorial Reviews

"The editors, all very accomplished and extremely knowledgeable of the field, assembled a fine collection of authors to write on the widely varied topics. … a very good compilation on brachytherapy physics and the current state of the practice …"
—Bruce Thomadsen, Medical Physics, November 2013

"… an excellent reference text which represents the current status of brachytherapy for all clinical sites and sets the scene for how it will continue to progress. Readers will be particularly pleased to find discussions on margin concepts, radiobiology and 3- and 4-D imaging modalities for planning, as well as a thorough review of a range of modern techniques. … The amount of detail included is extensive … Excellent references are given throughout. … This will certainly be a key reference for today’s brachytherapy centres."
SCOPE, March 2013

"This book … addresses the topic of brachytherapy from many vantage points, oncological, physical, and biological, and will satisfy readers from the entire radiotherapy community."
—From the Foreword by Pierre Scalliet

"Certainly, the frontier has been pushed in several directions and Comprehensive Brachytherapy covers some of these well… Overall, it is a very good compilation of brachytherapy physics and the current state of the practice…"
—Bruce Robert Thomadsen, Ph.D., University of Wisconsin-Madison, USA