The Laboratory Rat, Second Edition

The Laboratory Rat, Second Edition

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ISBN 9781439829868
Cat# K11462
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Features

    • Presents essential information for the care of laboratory rats and how to effectively use them in a wide variety of research applications
    • Illustrates management practices and technical procedures in a clear, easy-to-follow format that can easily be incorporated into a facility's standard performance procedures
    • Includes more than 70 full-color illustrations
    • Provides additional sources of information on rat biology, husbandry and veterinary care, and facility management
    • Contains tables on analgesic and anesthetic agents, methods of euthanasia, injection sites, and more

    Summary

    Rats have long been recognized as a valuable biomedical research model, notably in the investigation of aging, toxicology, addiction, and common human diseases such as diabetes and hypertension. In many instances, individuals conducting such research studies are charged with important responsibilities, including animal facility management, animal husbandry, veterinary care, regulatory compliance, and various experimental methodologies. With the advent of genetic manipulations and biomedical research technological advances such as bioimaging, the versatility and usefulness of the rat as an animal model has soared.

    The Laboratory Rat, Second Edition captures the multiple advances in this important animal model’s husbandry, veterinary care, and experimental methodology. This edition features augmented, expanded, and novel information on biology, anesthesia, analgesia, and experimental techniques benefiting personnel working with rats—from the animal care staff to the researcher and everyone in between. The book is also extremely useful to institutional animal care and use program supporters and elements, including animal care and use committees, institutional officials, occupational health and safety professionals, veterinary technicians, and veterinarians.

    Table of Contents

    Important Biological Features
    Introduction
    Nomenclature
    Behavior
    Anatomical and Physiological Features
    Hematology and Clinical Chemistry
    Reproduction

    Husbandry
    Housing
    Environmental Enrichment
    Nutrition
    Sanitation and Sanitation Monitoring
    Transportation
    Quality Control
    Identification and Records

    Management
    Overview
    Select Regulatory Agencies and Compliance
    Voluntary Accreditation
    Occupational Health/Zoonotic Diseases

    Veterinary Care
    Clinical History
    Physical Examination
    Diagnostic Imaging
    Diseases of Rats
    Disease Prevention, Treatment, and Control
    Detecting and Preventing Infectious Disease
    Anesthesia and Analgesia
    Aseptic Surgery
    Euthanasia
    Necropsy

    Experimental Methodology
    Restraint
    Sampling Techniques
    Compound Administration
    Other Techniques
    Common Research Uses of Rats
    Other Rats Used in Research

    Resources
    Organizations
    Publications
    Electronic Resources
    Equipment and Facilities Meetings
    Technical Education
    Vendors
    Research Animal Diagnostic Laboratories
    Research Support
    Sanitation Supplies
    Transportation
    Veterinary and Surgical Supplies

     
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