1st Edition

Reversibility of Chronic Disease and Hypersensitivity, Volume 3 Clinical Environmental Manifestations of the Neurocardiovascular Systems

By William J. Rea, Kalpana Patel Copyright 2015
    414 Pages 98 B/W Illustrations
    by CRC Press

    Encyclopedic in scope, Reversibility of Chronic Degenerative Disease and Hypersensitivity, Volume 3: Environmental Manifestations of the Neurocardiovascular Systems draws deeply from clinical histories of thousands of patients. It focuses on clinical syndromes within the musculoskeletal, neurological, and cardiovascular systems with a special focus on vascular dysfunction and heart failure treatment.

    The book explores mechanisms of chemical sensitivity and chronic degenerative disease, their manifestations, diagnosis, and approaches to reverse dysfunction. It covers a wide variety of topics including environmental sensitivity due to external pollutants, environmental control for reducing total body load, pollutant damage to vascular perfusion, altered blood volume, fluctuations of oxygen extraction, effects of endocrine on the vascular system, effects of pollutants on myocardial cells, and mechanisms in vascular damage.

    The book also discusses in detail a wide variety of clinical manifestations including vasculitis, cardiac arrhythmias, cardiac metabolic syndrome, myocarditis, atherosclerosis, heart failure, urticaria, and anaphylaxis. Treatment for heart failure is also discussed. The third volume of a five-volume set, the book provides an essential resource for health care providers diagnosing and treating chemical sensitivity and chronic degenerative disease.

    INTEGRATION OF THE MUSCULOSKELETAL AND NEUROLOGICAL SYSTEMS

    Introduction

    Entry of Environmental Pollutants: External and Internal Mechanisms of the Total Body Pollutant Load
    External Pollutants
    Internal Excitotoxins

    Environmental Control for Reducing Total Body Load
    ECU Construction and Maintenance
    Use of the ECU
    Summary

    VASCULAR FUNCTION AND DYSFUNCTION

    Introduction to the Cardiovascular System in Chemical Sensitivity

    Physiology and Pollutant Damage to Vascular Perfusion: Changes in the Sympathetic Nervous System Function
    Physiology of Vascular Perfusion
    Autonomic Nervous System
    Connective Tissue
    Endothelins
    Vascular Injury due to Pollutants
    Neovascularization
    Regional Perfusion Injury

    Blood Volume

    Effects of Pollutants on the Clotting System

    Oxygen Extraction

    Effects of Pollutants on Myocardial Cells


    Types of Mechanisms in Vascular Damage
    Nonimmune Mechanisms
    Immune Mechanisms

    Effects of Endocrine on the Vascular System

    Pollutant Entry in Dyshomeostasis: Clinical Syndromes
    Vasculitis
    Small Vessel Vasculitis
    Large Vessel Vasculitis
    Hypersensitive Vasculitis
    Eosinophilic Vasculitis
    Recurrent Phlebitis
    Cardiac Arrhythmias and Dysfunction
    Sudden Cardiac Death
    Hereditary Angioedema
    Urticaria
    Anaphylaxis
    Cardiac Metabolic Syndrome
    Cardiomyopathy
    Myocarditis

    Atherosclerosis
    Environmental Aspects of Atherosclerosis
    Cardiac Events and Hospital Admission
    Changes in Heart Rate and Cardiac Function
    Influence of Particulates
    Pathophysiology Leading to Inflammation
    Inflammation Mechanism
    Myocardial Necrosis and Toxic Infarction
    Cardioprotection
    Apoptosis
    Toxic Infarction
    Triggering Agents of CAD

    Heart Failure
    Introduction
    Heart Failure Pathology and Cell Communication
    Heart Failure Pathophysiology
    Energy-Starvation Hypothesis

    Heart Failure Treatment
    Classic Medical Treatment
    Neural Humeral Activation
    Emerging Therapeutic Options: Nutrients
    Summary

    Index

    Biography

    William J. Rea is a thoracic, cardiovascular, and general surgeon with an added interest in the environmental aspects of health and disease. He received his MD from The Ohio State University and was chief of thoracic surgery at the Veteran’s Hospital in Dallas. He has lectured on cardiovascular and thoracic surgery at the University of Texas S.W. Medical School and on environmental sciences at the University of Texas. Dr. Rea served on the board of the American Academy of Environmental Medicine and is currently a board member of the American Board of Environmental Medicine. Dr. Rea is a fellow of the American Academy of Environmental Medicine, the American College of Surgeons, and the Royal Society of Medicine. He was part of the team who resuscitated Governor John Connally when President Kennedy was shot.

    Kalpana D. Patel is a pediatrician with an added interest in the environmental aspects of health and disease. She serves as an assistant professor of pediatrics at the State University of New York at Buffalo. Dr. Patel was awarded the Jonathan Forman Gold Medal Award for outstanding research in environmental medicine and the Herbert J. Rinkel Award for outstanding teaching by the American Academy of Environmental Medicine. Dr. Patel has served as president of the American Board of Environmental Medicine and is currently a member of its executive committee. She has also served on the board of the American Academy of Environmental Medicine and is a diplomate of both the American Board of Pediatrics and the American Board of Environmental Medicine. Dr. Patel is a fellow of the American Academy of Environmental Medicine.