Now in its second edition, this volume provides focused, single-source coverage of the instrumentation, computerization, calibration, and methods development of NIR spectroscopy. It examines novel applications for accurate time- and cost-effective analyses of pharmaceuticals as well as biomedical applications. Fully updated, the book contains entirely new chapters on the theory of diffuse reflection, the calibration and validation of process sensors, the new field of PAT (Process Analytical Technologies) in pharmaceutical applications, nutraceuticals, detection of counterfeit drugs, NIR spectrometry of abdominal aortic aneurysm, and new chemometric methods for biomedical components in blood and control serum.
Basic Principles and Theory. NIR Instrumentation. Blend Uniformity Analysis. Granulation, Drying, and Coating. Pharmaceutical Assays. Validation Issues. Medical Applications. Index.