Physiology, Biophysics, and Biomedical Engineering

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ISBN 9781420065138
Cat# C6513



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ISBN 9781439891360
Cat# KE14793



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  • Offers a multidisciplinary approach to human biological systems
  • Highlights the application of physics and engineering methods to medicine and biology
  • Gives readers a solid basis for understanding the physiological processes in the human body
  • Draws on the classroom material of experienced lecturers
  • Incorporates a range of numerical problems with worked solutions
  • Provides MATLAB® code for advanced mathematical analysis of physiological and clinical monitoring systems
  • Includes references to further reading at the end of each chapter

Solutions manual available with qualifying course adoption


Physiology, Biophysics and Biomedical Engineering provides a multidisciplinary understanding of biological phenomena and the instrumentation for monitoring these phenomena. It covers the physical phenomena of electricity, pressure, and flow along with the adaptation of the physics of the phenomena to the special conditions and constraints of biological systems. While the text focuses on human biological systems, some of the principles also apply to plants, bacteria, and other animals.

The first section of the book presents a general introduction to physiological systems and describes specialized methods used to record electrical events from biological tissue. The next part examines molecules involved in cell transport and signaling as well as the proteins relevant in cells’ ability to contract and generate tension. The text goes on to cover the properties of the heart, blood, and circulation and the monitoring of cardiac and circulatory function. It then discusses the importance of the interrelationship of pressures and flows in organ systems, such as the lungs and kidneys, and details the organization and function of the nervous system. After focusing on the systems used to monitor signals, the book explores modeling, biomechanics, and emerging technologies, including the progressive miniaturization of sensors and actuators in biomedical engineering.

Developed from the authors’ courses in medical biophysics and biomedical instrumentation, this book shows how biophysics and biomedical engineering have advanced modern medicine. It brings together the physical principles underlying human physiological processes and the physical methods used to monitor these processes. Requiring only basic mathematical knowledge, the text supplements mathematical formulae with qualitative explanations and illustrations to encourage an intuitive grasp on the processes discussed.

Table of Contents

Introduction to Physiological Systems, Andrew W. Wood
Fundamentals of Electrical Circuits for Biomedicine, Anthony Bartel and Peter Alabaster
Properties of Electrodes, Andrew W. Wood

Molecular Biophysics, Andrew W. Wood
Membrane Biophysics, Andrew W. Wood
Excitability and Synapses, Andrew W. Wood
Skeletal Muscle Biophysics, Per Line

Cardiac Biophysics, Andrew W. Wood
Rheology of Blood, Andrew W. Wood
The Vascular System: Blood Flow Patterns in Various Parts of the Circulation, Andrew W. Wood
Cardiovascular System Monitoring, Andrew W. Wood

Respiratory Biophysics, Bruce R. Thompson and Joseph Ciorciari
Renal Biophysics and Dialysis, Andrew W. Wood
Cardiopulmonary Perfusion and Advanced Surgical Techniques, Andrew W. Wood

Organization of the Human Central Nervous System, Per Line
The Biophysics of Sensation—General, Mark A. Schier and Andrew W. Wood
Vision, David P. Crewther
Audition and Vestibular Sense, Joseph Ciorciari
Chemical Senses, John Patterson

Physiological Signal Processing, Peter J. Cadusch
Bioelectrical Signals: The Electroencephalogram, Joseph Ciorciari
Magnetic Stimulation and Biomagnetic Signals, Andrew W. Wood
Medical Imaging, Andrew W. Wood
Microscopy and Biophotonics, Andrew W. Wood

Physiological Modeling, Andrew W. Wood
Biomechanics and Biomaterials, Andrew W. Wood
Biosensors and Emerging Technologies, Andrew W. Wood

Answers to Questions


Editor Bio(s)

Andrew W. Wood is a professor in the Brain and Psychological Sciences Research Center at Swinburne University of Technology. Dr. Wood was recently a member of the radiation health committee of the Australian Radiation Protection and Nuclear Safety Agency and the secretary and registrar of the Australian Radiation Protection Accreditation Board. His research interests include the health effects associated with nonionizing radiation, cellular neuroscience, fluorescence microscopy, and mathematical modeling.

Editorial Reviews

"The book is strongly recommended to statisticians who wish to work in this relatively new, still emerging field of engineering, which will have to draw on both biology and statistics in the future."
—Jayanta K. Ghosh, International Statistical Review (2013), 81

"The inclusion of sample problems with solutions and well balanced illustrations when appropriate make this book one of the most highly recommended for those interested in understanding the underlying physical phenomena of biomedical research. …a valuable resource for medical professionals and students involved in physical medicine practice, medical device development, diagnostic design, and medical physics, particularly those interested in applied physics and engineering to medicine."
—Paul Gueye, PhD, Hampton University, Virginia, USA