Nicotinic Receptors in the Nervous System

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$169.95
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ISBN 9780849323867
Cat# 2386
 

Features

  • Uses an approach that integrates molecular and neurochemical behavioral applications in translational animal behavior models and clinical applications
  • Presents the work of distinguished researchers in the field
  • Includes the latest reviews of nicotine research on the molecular, neurochemical, translational, and clinical levels of analysis
  • Discusses the function of neural nicotinic systems and the significance for diseases such as schizophrenia, Alzheimer's disease, Tourette's syndrome, and ADHD
  • Summary

    Nicotine research has been conducted for the better part of a century, but with the discovery of the relationship of nicotinic systems to Alzheimer's disease, the differentiation of nicotinic receptor subtypes, and the development of novel nicotinic ligands, the field of nicotine research has exploded. This book will provide you reference to the latest research methods and findings concerning nicotinic neural systems.

    Featuring a unique approach, Nicotinic Receptors in the Nervous System provides integrated coverage of cutting-edge research concerning neuronal nicotinic systems relevant to smoking addiction and cognitive dysfunction. By bringing together molecular and neurochemical applications, this book provides the key to understanding function and dysfunction of nicotinic systems and how they are significant for disease, addiction, and the development of novel drug treatments.

    Within the next several years, it is very promising that clinical research will support the use of nicotinic treatments for addiction, pain, and cognitive and motor dysfunction. Nicotinic Receptors in the Nervous System provides you with the basic mechanistic background for these treatments as well as the functional assessment necessary to determine therapeutic effects.

    Table of Contents

    Some Methods for Studies of Nicotinic Acetylcholine Receptor Pharmacology, R.J. Lukas, J.D. Fryer, J.B. Eaton, and C.L. Gentry

    Presynaptic Nicotinic Acetylcholine Receptors: Subtypes Mediating Neurotransmitter Release, S. Wonnacott, A. Mogg, A. Bradley, and I.W. Jones
    Nicotinic Receptors in the Periphery

    Effects of Nicotine on Dopaminergic Neurotransmission, P.P. Rowell

    Nicotinic Receptors in the Periphery, S. Jones, H. Lo, and S.A. Simom

    Nicotinic Cholinergic Receptors as Targets in Pain Control, M.I. Damaj and C.M. Flores

    Mouse Models to Evaluate Genetic Influences on Responses to Nicotine, M.J. Marks and A.C. Collins

    Nicotinic Involvement in Cognitive Function in Rats, E.D. Levin and A.H. Rezvani

    Nicotine and Cognition in Young and Aged Nonhuman Primates, J.J. Buccafusco and A.V. Terry, Jr.

    Evaluation of Pharmacologic Treatments for Smoking Cessation, J.E. Rose

    Nicotine and Schizophrenia, J.P. McEvoy

    Nicotinic Medications and Tourette's Disorder, R.D. Shytle, A.A. Silver, M. Newman, B.J. Wilkinson, and P.R. Sandberg

    Nicotine Effects on Attention Deficit Hyperactivity Disorder, E.D. Levin

    Clinical Methodologies in the Examination of Nicotinic Effects, A. Potter and P.A. Newhouse

    Nicotinic Systems: An Integrated Approach, E.D. Levin

    Editorial Reviews

    "Well known researchers from the Old and New Worlds contributed to this book…presents an integrated approach to nicotine research that should help to identify critical neuropharmacological mechanisms for both adverse and potentially therapeutic effects of nicotine. Edward Levine has contributed much to the development of nicotine research on cognitive functions."
    Jacques le Houezec, SRNT Newsletter, October/November 2002

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