Neurobehavioral Genetics: Methods and Applications, Second Edition
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Summary
A complete background to concepts and principles of behavioral genetics, Neurobehavioral Genetics: Methods and Applications, Second Edition features a broad spectrum of the most current techniques in neurobehavioral genetics in a single source.
International researchers incorporate several new developments in the field, including:
Based on various studies of living organisms ranging from primates to rodents to invertebrates, this edition offers a contemporary approach to examining the relationship between the genetic mechanisms in the brain and behavior. The authors examine how past and recent advances in methods and knowledge come together in the comparative genetics of behavior. They introduce the reader to experimental approaches available for the genetic study of emotionality, focusing on the use of animal models.
This edition explores studies in neurogenetic disorders, including schizophrenia and bipolar disorders, examines genetic traits in personality such as altruism, and evaluates aggression in mice and humans. It also discusses the applications of quantitative methods and molecular genetics in basic and clinical research.
Neurobehavioral Genetics: Methods and Applications, Second Edition brings together new techniques and methods to promote a better understanding of genetics and their effects on behavior. The book is an excellent resource for investigators who want to incorporate genetic methods into neurobehavioral and psychiatric research.
Table of Contents
Background and Basic Concepts
A History of Behavior Genetics; Stephen C. Maxson
Developmental Neurobehavioral Genetics: Development as Explanation; Gilbert Gottlieb
Some Basics: Mendelian Traits, Polygenic Traits and Complex Traits; Byron C. Jones
An Introduction to Quantitative Principles; Wim E. Crusio
Methods
From QTL Detection to Gene Identification; Marie-Pierre Moisan
Gene expression; Richard A. Radcliffe
Bioinformatics of Behavior; Elissa J. Chesler
Congenic and Consomic Strains; Lorraine Flaherty and Valerie Bolivar
Animal Resources in Behavioral Neurogenetics; Jean-Michel Lassalle
Sample Size Requirements for Experiments on Laboratory Animals; Douglas Wahlsten
Studies in Hominids
Neurobehavioral Genetics: The Role of Association Studies in Psychiatric Disorders; Nicolas Ramoz and Phillip Gorwood
Family and Twin Methods; Keith E. Whitfield
Gene-environment interactions; Byron C. Jones and Leslie C. Jones
And Now it Starts to Get Interesting: Gene-gene interactions; Yamima Osher
Schizophrenia: Study of a Genetically Complex Phenotype; Michael Pogue-Geile and Irving Gottesman
Genetics of Major Affective Disorders; Wade Berrettini
Pedigree Analyses and the Study of Chimpanzee (Pan troglodytes): Personality and Subjective Well-Being; Alexander Weiss and James E. King
The Elusive World of Personality Genes: Cherchez le phenotype; Richard P. Ebstein, Rachel Bachner-Melman, Jonathan Benjamin and Robert H. Belmaker
Studies in Rodents
Aggression: Concepts and Methods Relevant to Genetic Analyses in Mice and Humans; Stephen C. Maxson and Andrew Canastar
Genetic Analysis of Emotional Behaviors Using Animal Models; André Ramos and Pierre Mormède
Studies in Invertebrates
Genetic Analysis of Food Search Behavior in the Fruit Fly (Drosophila melanogaster); Amsale T. Belay and Marla B. Sokolowski
Genetic and Molecular Analysis of Drosophila Courtship Behavior; Jean-Marc Jallon
A New Era for Drosophila Learning and Memory Studies; Daniel Comas, Guillaume Isabel, and Thomas Préat
Behavioral Genetics in the Nematode Caenorhabditis Elegans; Gert Jensen and Laurent Ségalat
Bridging Neurobiology and Behavior
Genetics, Behavior and Brain Dopamine Systems; Robert Hitzmann, Shannon McWeeney, and John K. Belknap
Natural Genetic Variation of Hippocampal Structures and Behavior; Hans-Peter Lipp, Irmgard Amrein, Lutz Slomianka, and David P. Wolfer
Expression and Brain Structure: Black Boxes between Genes and Behaviors; Jeremy L. Peirce, Robert W. Williams
Synaptic Mechanisms Involved in Cognitive Function: Cues From Mental Retardation Genes; Guntram Borck, Florence Molinari, Birgit Dreier, Peter Sonderegger and Laurence Colleaux
Pharmacology
Pharmacogenetics; Byron C. Jones
Alcohol Psychopharmacogenetics; John C. Crabbe
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