Interest in biodegradable and absorbable polymers is growing rapidly in large part because of their biomedical implant and drug delivery applications. This text illustrates creative approaches to custom designing unique, fiber-forming materials for equally unique applications. It includes an example of the development and application of a new absorbable system, a condensed encyclopedia on novel PEG-based copolyesters, and the first comprehensive discussion of a novel class of absorbable tissue adhesives. The book also provides up-to-date information on important tissue engineering technologies and approaches to utilizing these technologies for long awaited practical applications.
INTRODUCTION NOTES: Absorbable/Biodegradable Polymers: Technology Evolution. DEVELOPMENT AND APPLICATION
OF NEW SYSTEMS: Segmented Copolyesters with Prolonged Strength Retention Profiles. Polyaxial Crystalline Fiber-Forming Copolyester. Polyethylene Glycol-Based Copolyesters. Cyanoacrylate-Based Systems as Tissue Adhesives. Chitosan-Based Systems. Hyaluronic Acid-Based Systems. DEVELOPMENTS IN PREPARATIVE, PROCESSING, AND EVALUATION METHODS: New Approaches to the Synthesis of Crystalline. Fiber-Forming Aliphatic Copolyesters. Advances in Morphological Development to Tailor the Performance of Medical Devices. Polymer Biocompatibility and Toxicity. GROWING AND NEWLY SOUGHT APPLICATIONS: Tissue Engineering Systems. Synthetic Vascular Constructs. Postoperative Adhesion Prevention. Implantable Insulin Controlled Release Systems. for Treating Diabetes Mellitus. Absorbable Delivery Systems for Cancer Therapy. Tumor Immunotherapeutic Systems.