Aspirin and Related Drugs

Published:
Editor(s):

Purchasing Options

Hardback
$199.95
Add to cart
ISBN 9780748408856
Cat# TF2245
 

Features

  • Discusses many non-conventional aspects of the use and actions of aspirin
  • Provides concept-type diagrams that illustrate mechanisms of action or applications of aspirin and its derivatives
  • Includes contributions from leading authorities in the specialties covered
  • Summary

    Reviewing over a century of aspirin research and use, Aspirin and Related Drugs provides a comprehensive source of information on the history, chemistry, absorption in the body, therapeutic effects, toxicology, elimination, and future uses of aspirin.

    Highlighting the historical evolution of the salicylates and the commercial development of aspirin, the book reviews the pharmacokinetics of the salicylates, ibuprofen, and paracetamol as a basis for understanding the biodisposition of these analgesic drugs. Leading specialists discuss the therapeutic role of aspirin in the prevention and treatment of thrombo-embolic diseases, its place along with non-acetylated salicylates in the treatment of rheumatic diseases and plain, and the potential applications for aspirin and related drugs as prophylactics for colon cancer, Alzheimer's disease, and vascular dementia. They also present comparisons with other drugs used to treat pain and inflammation.

    With extensive data and literature covering a broad field, this is the definitive reference on the actions and applications of aspirin, salicylates, and related drugs. Physicians, pharmacists, pharmacologists, toxicologists, and chemists will find this resource useful in their daily work. It will also be valuable to pharmaceutical companies and researchers in the development of newer agents and novel applications.

    Table of Contents

    History and Development of the Salicylates, K.D. Rainsford
    The Industrial History of Analgesics: The Evolution of Analgesics and Antipyretics, J.R. McTavish
    Occurrence, Properties and Synthetic Developments of the Salicylates, K.D. Rainsford
    Pharmacokinetics and Metabolism of the Salicylates, G.G. Graham, M.S. Roberts, R.O. Day, and K.D. Rainsford
    Metabolism and Pharmacokinetics of Ibuprofen, G.G. Graham and K.M. WIlliams
    Pharmacokinetics and Metabolism of Paracetamol (Acetaminophen), G.G. Graham and M. Hicks
    Pharmacology and Biochemistry of Salicylates and Related Drugs, K.D. Rainsford
    Side-effects and Toxicology of the Salicylates, K.D. Rainsford
    Reye's Syndrome and Aspirin, J.F.T. Glasgow and S.M. Hall
    Salicylates in the Treatment of Acute Pain, K.D. Rainsford
    Acetysalicylic Acid for the Prevention and Treatment of Thromboembolic Diseases, K.E. Webert and J.G. Kelton
    Use of Salicylates in Rheumatic and Related Conditions, W.W. Buchanan, W.F. Kean, and K.D. Rainsford
    Aspirin and NSAIDs in the Prevention of Cancer, Alzheimer's Disease and other Novel Therapeutic Actions, K.D. Rainsford

    Related Titles