Debasis Bagchi

Biography

Debasis Bagchi received his Ph.D.in Medicinal Chemistry. He is a Professor in the Dept of Pharmacological and Pharmaceutical Sciences at University of Houston, TX. Dr. Bagchi is also the Director of Innovation & Clinical Affairs of Iovate Health Research Inc., Oakville, ON L6M 0H4. Dr. Bagchi is the Immediate Past President of the American College of Nutrition, Clearwater, FL, Distinguished Advisor on the Japanese Institute for Health Food Standards, Tokyo, Japan.

CURRICULUM VITAE
Industrial Address:
Research & Development Division
Iovate Health Sciences Research Incorporated
381 North Service Road West
Oakville, ON L6M 0H4, CANADA
Phone: (905) 290 4380; Fax: (905) 678 4095
Email: [email protected]

Home Address:
25 Kingsbridge Garden Circle, Mississauga, ON L5R 4B1, CANADA
Phone: (647) 857 9939; Cell: (416) 525 6496
U.S. Citizen

Education:
1982 Ph.D. in Medicinal Chemistry, Indian Institute of Chemical Biology, Calcutta, India
1980 A.M.I.I.Chem.E., Indian Institute of Chemical Engineers, Calcutta, India
1976 M.Sc. in Chemistry, Jadavpur University, Calcutta, India (First Class)
1973 B.Sc. (Chemistry Hons), Jadavpur University, Calcutta, India (First Class)

Professional Experience:
02/11- Director, Innovation & Clinical Affairs, Iovate Health Sciences Research Inc., Oakville, ON, Canada
07/08- Adjunct Professor, Departments of Pharmacological and Pharmaceutical Sciences, University of Houston College of Pharmacy, Houston, TX
10/04 – 02/11 Senior Vice President, Research and Development, InterHealth Nutraceuticals
Inc., Benicia, CA
08/00 - 06/08 Part-Time Professor, Department of Pharmacy Sciences, School of Pharmacy and
Health Professions, Creighton University Medical Center, Omaha, NE
08/00 - 10/04 Vice President, Research and Development, InterHealth Nutraceuticals Inc., Benicia, CA
01/98 - 08/00 Director, Research and Development, InterHealth Nutraceuticals Inc., Concord, CA
07/93 - 08/00 Associate Professor, Pharmaceutical and Administrative Sciences, Creighton University School of Pharmacy & AHP, Omaha, NE
01/91-06/93 Assistant Professor, Dept. of Pharmaceutical Sciences, Creighton University, Omaha, NE
10/90-12/90 Post-Doctoral Fellow, Department of Surgery, University of Connecticut School of Medicine, Farmington, CT
08/88-09/90 Development Manager, Research & Development, Berger India Limited, Calcutta, India.
07/87-07/88 Post-Doctoral Fellow, Department of Surgery, University of Connecticut School of Medicine, Farmington, CT
01/86-07/87 Post-Doctoral Fellow, Chemistry Department, Bowling Green State University, Ohio
12/81-12/85 Research and Development Officer, Berger India Limited, Calcutta, India.
03/77-12/81 Research Fellow, Medicinal Chemistry Division, Indian Institute of Chemical Biology (CSIR), Calcutta, India

Industrial Expertise:
• Extensively Researched and Developed a Broad Spectrum of Diverse Supplements including (i) Weight Mangement Supplements including Super CitriMax, OMAC, LOWAT, Merastin, and others, (ii) Metabolic Syndrome Supplements including ChromeMate [chromium (III) polynicotinate], chromium picolinate, Zychrome [chromium (III) dinicocysteinate](received Nutracon Best Supplement Award in 2012), and several other chromium (III) supplements, (iii) Arthritis Supplements on Undenatured Collagen II (UC-II), Chondroitin Sulfate, MSM, Glucosamine Hydrochloride and Hyaluronic Acid, (iv) Antioxidant Supplements including ActiVin (grape seed proanthocyanidin extract), OptiBerry (a Novel Combination of Six Edible Berries including Blueberry, Bilberry, Elderberry, Strawberry, Cranberry and Raspberry Seeds); trans-Resveratrol, Vitamin E Succinate, Lycopene, and others, (v) Exercise, Sports Nutrition and Muscle Building Supplements including Several Structurally Diverse Amino Acids, Carnitine, GAKIC, β-Hydroxy β-methylbutyric acid (HMB), Whey Proteins and Others; (vi) Others including Zinc, Magnesium and Vanadium Supplements; and (vii) A Broad Spectrum Botanical Ayurvedic Extracts
• Overseeing and Managing All Technical and Research Information Required by the Company for Sales, Marketing, Customer Service and Regulatory Affairs Activities.
• Ensuring that All Sales, Marketing and Customer Service Personnel are Educated and Kept Fully Informed on All Existing and New Product Information including Product Specifications, Research Studies, Analytical Data and Competitive Information.
• Develop a Novel Strategy to Implement New Safe and Efficacious Products Based on Scientific and Clinical Investigations.
• Managing and Upgrading Product Information Training Manuals and Power Point Presentation Kits, and Organizing Training Seminars for Sales and Marketing Teams and Key Customers with In-House Scientists and Guest Professors/Scientists on a Monthly Basis.
• Organize, Direct and Perform Training Sessions in the R&D, Collaborate with Marketing and Sales Team, and Coordinate to Enhance Company’s Growth and Business Development.
• Design and Execute Research Activities to Support Structure Function Claims of Products and Develop a Novel Communication Strategy with Sales and Marketing.
• Review Safety and Toxicity Parameters, Design and Conduct A Broad Spectrum of Safety Studies and Obtain GRAS Approval As and When Required.
• Develop Novel Concepts and Grow Company’s Intellectual Property and Patent Portfolio.
• Present Research Data in Scientific Conferences and Publish in Peer-Reviewed Journals. Organize Scientific Seminars for Key Customers.
• Identify, Develop and Introduce New Products Supported by Scientific Research and Peer-Reviewed Publications. Also, Authoring White Papers as Requested by Sales and/or Marketing from time to time.
• Design, Develop and Implement New and Novel Analytical Techniques for Product Characterization and Quantification.
• Closely Monitor to Maintain Regulatory Compliances in the Company on a Regular Basis.

Newsworthy Accomplishments in the Industry till Date:
• Associated with the Developments of numerous Weight Loss, Muscle Building and Sports Nutrition Formulations substantiated by fundamental, animal and human clinical studies. Intricately associated with the developments of numerous Sports Nutrition and Muscle Building formulations involving structurally diverse Amino acids, Whey Proteins, GAKIC, Ursolic and Maslinic Acid.
• Successfully completed and published a series of Safety Studies and Obtained GRAS Status on Super CitriMax, a Novel Supplement for Weight Management, and ChromeMate, a Novel Niacin-Bound Chromium (III) for favorably regulating glucose-insulin sensitivity, and UC-II (Undenatured Collagen II), demonstrating its Efficacy against Joint Pain and Inflammation. Extensively Worked on a number of leading Weight Management Supplements including OMAC, LOWAT, Merastin and Zychrome.
• Designed a unique Human Clinical Study jointly with Georgetown University Medical Center, Executed and Published Human Clinical Studies on Super CitriMax.
• Designed and Published Several Human Clinical Studies on ActiVin, Super CitriMax, ChromeMate, UC-II and Aller-7.
• Designed and Completed Nutragenomics Study to Identify Obesity Regulatory Genes Modulated by Super CitriMax and ChromeMate.
• Obtained GRAS Status on Super CitriMax and ChromeMate.
• Designed and Published more than 36 Peer-Reviewed Publications on ActiVin, a Novel GRAS-approved Grape seed-derived Proanthocyanidin Antioxidant.
• Demonstrated the Novel Anti-Angiogenic Properties of OptiBerry, a Novel combination of Berry Anthocyanins, in both in vitro and in vivo models for Human Consumption and Cosmetic Applications.
• Designed and Published Mechanistic and Human Clinical Studies on Aller-7, a Novel Polyherbal Formulation from Medicinal Plants Designed to Ameliorate allergic rhinitis.
• Designed and Conducted Research Projects on Niacin-Bound Chromium to Ameliorate the Symptoms of Syndrome X. Published in Peer-Reviewed Journals.
• Designed and Completed Safety, Mechanistic and Human Clinical Studies on Undenatured Collagen II (UC-II), demonstrating its Efficacy Against Joint Pain.
• Developed a Novel, Water-Soluble, State-of-the-Art New-Generation Chromium(III) Supplement “Zychrome” for Humans and Animals.
• Developed a Novel, State-of-the-Art Energy Formula with Published Safety and Efficacy Data.
• Introduced a Number of New Products and Formulations in the Dietary Supplement and F&B (Food & Beverage) Market
• Obtained a NIH SBIR Phase I Grant of $ 149,800 from National Institutes of Health to Demonstrate the Pharmacologic Preconditioning Potential of Protykin, a Novel 50% Natural Extract of trans-Resveratrol from Polygonum cuspidatum.
• Published a significant number of peer-reviewed publications on these products in Food, Nutrition and Biochemistry Journals.

Books and Special Issues Edited
2001 Nutritional Proanthocyanidins, Flavonoids, and Related Phenols (Eds. D. Bagchi & C.A. Rice-Evans) Mary Ann Liebert, Inc. Antioxidants & Redox Signaling 3(6):939-1166.
2004 Nutraceutical and Functional Food Industries: Aspects on Safety and Regulatory Requirements (Eds. D. Bagchi, J.P. Kehrer & H.G. Preuss), Elsevier, Toxicology Letters 50(1):1-134.
2005 Phytopharmaceuticals in Cancer Chemoprevention (Eds. D. Bagchi & H.G. Preuss) CRC Press LLC, Boca Raton, FL. (665 pages)
2006 Nutraceuticals and Functional Foods Regulations in the United States and Around the World (Ed. D. Bagchi) Elsevier. Toxicology 221(1):1-134.
2007 Obesity: Epidemiology, Pathophysiology and Prevention (Eds. D. Bagchi & H.G. Preuss CRC Press LLC, Boca Raton, FL. (569 pages)
2007 Anti-Angiogenic Functional and Medicinal Foods (Eds. D. Bagchi, J.N. Losso & F. Shahidi) CRC Press LLC, Boca Raton, FL. (715 pages)
2008 Nutraceuticals and Functional Foods Regulations in the United States and Around the World (Ed. D. Bagchi) Elsevier/Academic Press, Amsterdam, Holland. (462 pages)
2009 Genomics, Proteomics and Metabolomics in Nutraceuticals and Functional Foods (Eds. D. Bagchi, M. Bagchi & F.C. Lau) Wiley-Blackwell Co., Ames, IA. (338 pages)
2009 Nutraceuticals and Biotechnology (Eds. D. Bagchi, F.C. Lau & D. Ghosh) CRC Press LLC, Boca Raton, FL. (573 pages).
2010 Global Perspectives on Childhood Obesity (Ed. D. Bagchi) Elsevier/Academic Press, Amsterdam, Holland (521 pages).
2011 Arthritis Pathophysiology, Prevention and Therapeutics (Eds. D. Bagchi, H. Moriyama & S.P. Raychaudhuri) CRC Press LLC, Boca Raton, FL. (577 pages).
2012 Nutritional and Therapeutic Interventions of Diabetes and Metabolic Syndrome (Eds. D. Bagchi & S. Nair) Elsevier/Academic Press, Amsterdam, Holland (536 pages).
2012 Recent Trends in Therapeutic Advancements of Free Radical Science (Eds. D. Bagchi, N. Maulik & E. Padmini) Informa Healthcare, New York, Toxicology Mechanisms and Methods (Coming out in May 2012).
2012 Obesity: Epidemiology, Pathophysiology and Prevention (Eds. D. Bagchi & H.G. Preuss) CRC Press LLC, Boca Raton, FL (Second Edition)(Coming out in June 2012).
2012 Chronic Inflammation: Molecular Pathophysiology, Nutritional and Therapeutic Interventions (Eds. S. Roy, D. Bagchi & S.P. Raychaudhuri) CRC Press LLC, Boca Raton, FL (Coming out in August 2012).
2012 Innovation in Healthy and Functional Foods (Eds. D. Ghosh, S. Das, D. Bagchi & R.B. Smarta) CRC Press LLC, Boca Raton, FL (Coming out in September 2012).
2012 Bionanotechnology: A Revolution in Food, Biomedical and Health Sciences (Eds. D. Bagchi, M. Bagchi, H. Moriyama & F. Shahidi) Wiley-Blackwell Co., Ames, IA. (Coming Out in December 2012)
2012 Currently Editing a book on Sports Nutrition, Exercise and Muscle Building for Elsevier/Academic Press, Amsterdam, Holland.

Teaching:
• Launched “Food and Nutrition Toxicology (PHA 477)” Online Course in August 2003 at Creighton University School of Pharmacy and Allied Health Professions as the Course Director.
• Launched “Principles of Toxicology (PHA 476)” Online Course in January 2002 at Creighton University School of Pharmacy and Allied Health Professions as the Course Director.
• Course Director and Instructor of the “Principles of Toxicology (PHA 476)” course at Creighton University School of Pharmacy and Allied Health Professions.
• Instructor of the “Scholarly Project (PHA 500)” course at Creighton University School of Pharmacy and Allied Health Professions.
• Supervise Medicinal Chemistry and Toxicology research projects of undergraduate and graduate pharmacy students on rotation at Creighton University School of Pharmacy and Allied Health Professions.

Honors:
2010 Awarded Master of American College of Nutrition, Clearwater, FL
2010 President, American College of Nutrition, Clearwater, FL
2009 Distinguished Advisor, the Japanese Institute for Health Food Standards, Tokyo, Japan.
2008 President Elect, American College of Nutrition, Clearwater, FL.
2008 Member, Corporate Advisory Board, University of Houston College of Pharmacy, Houston, TX.
2007 Chair, Nutraceuticals and Functional Foods Division, Institute of Food Technologists (IFT), Chicago, IL.
2007 President Elect of the American College of Nutrition, Clearwater, FL.
2006 Chair-Elect, Nutraceuticals and Functional Foods Division, Institute of Food Technologists, Chicago, IL.
2006 Reviewer of United States Army Research Grants on Gulf War Illness Research Program (AIBS)
2006 General Secretary and Treasurer, American College of Nutrition, Clearwater, FL.
2006 Member of Dean’s Scientific Advisory Council of University of Houston College of Pharmacy, Houston, TX.
2005 Elected as the General Secretary and Treasurer of the American College of Nutrition, Clearwater, FL.
2005 Member of the Board of Directors of the American College of Nutrition, Clearwater, FL.
2005 Member of Dean’s Scientific Advisory Council of University of Houston College of Pharmacy, Houston, TX.
2004 Elected as a Member of the Board of Directors of the American College of Nutrition, Clearwater, FL.
2004 Member of the Dean’s Scientific Advisory Council of University of Houston College of Pharmacy, Houston, TX.
2004 Served as the Council Coordinator of the “Dietary Supplements/Nutraceuticals/ Functional Foods/Vitamins Council” of the American College of Nutrition.
2003 Member of Dean’s Scientific Advisory Council of University of Houston College of Pharmacy, Houston, TX.
2003 Served as the Council Coordinator of the “Dietary Supplements/Nutraceuticals/ Functional Foods/Vitamins Council” of the American College of Nutrition.
2003 Appointed as a Member of the SSS-3 Study Section and Peer Review Committee of the National Institutes of Health (Bethesda, MD).
2002 Appointed as a Member of the SSS-3 Study Section and Peer Review Committee of the National Institutes of Health (Bethesda, MD).
2001 Appointed as a Member of the SSS-3 Study Section and Peer Review Committee of the National Institutes of Health (Bethesda, MD).
2000 Appointed as a Member of Peer Review Committee of the Gulf War Illness Research Program [Panel C Toxicity of Militarily Relevant Heavy Metals] organized by the American Institute of Biological Sciences (Washington, DC).
2000 Appointed as a Member of the SSS-3 Study Section and Peer Review Committee of the National Institutes of Health (Bethesda, MD).
1999 Appointed as a Member of the General Medicine A-2 and ALTX-4 Study Sections and Peer Review Committees of the National Institutes of Health (Bethesda, MD).
1995 Appointed as a member of the Ad Hoc Trichloroethylene Stakeholder Committee, Toxicology Division of the Armstrong Laboratory, Wright-Patterson Air Force Base, Dayton, Ohio

Membership of Learned Societies:
Society of Toxicology (Member)
American College of Nutrition (Fellow)
American Institute of Chemical Engineers (Member)
The New York Academy of Sciences (Member)
Society for Free Radical Biology and Medicine (SFRBM)
Phi Beta Delta (Honor Society for International Scholars)

Member of the Editorial Board:
• Journal of American College of Nutrition (Associate Editor)
• Journal of Functional Foods (Associate Editor)
• Antioxidants & Redox Signaling
• Cancer Letters
• Toxicology Mechanisms and Methods
• The Original Internist
• International Journal of Biomedical Science
• Research Communications in Pharmacology and Toxicology
• International Journal of Geriatric Urology and Nephrology (General Nephrology and Geriatric Nephrology Section)
• CRC Press, Boca Raton, FL (Consulting Editor)

Peer-Reviewed Publications: 284

Patents: 15

References: Available on request

Education

Ph.D., MACN, CNS, MAIChE

Areas of Research / Professional Expertise

His research interests include free radicals, human diseases, carcinogenesis, pathophysiology, mechanistic aspects of cytoprotection by antioxidants, regulatory pathways in obesity, diabetes and gene expression.

Personal Interests

Photography

Books