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Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials

1st Edition

John O'Quigley, Alexia Iasonos, Björn Bornkamp
August 08, 2019

Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials gives a thorough presentation of state-of-the-art methods for early phase clinical trials. The methodology of clinical trials has advanced greatly over the last 20 years and, arguably, nowhere greater than that of...

Life-Cycle of Structures Under Uncertainty: Emphasis on Fatigue-Sensitive Civil and Marine Structures

1st Edition

Dan M. Frangopol, Sunyong Kim
August 05, 2019

Life-cycle analysis is a systematic tool for efficient and effective service life management of deteriorating structures. In the last few decades, theoretical and practical approaches for life-cycle performance and cost analysis have been developed extensively due to increased demand on structural...

Feature Engineering and Selection: A Practical Approach for Predictive Models

1st Edition

Max Kuhn, Kjell Johnson
August 02, 2019

The process of developing predictive models includes many stages. Most resources focus on the modeling algorithms but neglect other critical aspects of the modeling process. This book describes techniques for finding the best representations of predictors for modeling and for nding the best subset...

Essentials of Statistics In Agricultural Sciences

1st Edition

Pradeep Mishra, Fozia Homa
July 25, 2019

An understanding of the basics, logic, and theory of statistics is essential for agricultural researchers for dealing with the interpretation of data. This volume presents some of the basic and necessary concepts of statistical tools, specifically as applied to the statistics of agriculture and...

Sturge's Statistical and Thermal Physics, Second Edition

2nd Edition

Jeffrey Olafsen
July 19, 2019

The original work by M.D. Sturge has been updated and expanded to include new chapters covering non-equilibrium and biological systems. This second edition re-organizes the material in a more natural manner into four parts that continues to assume no previous knowledge of thermodynamics. The four...

Disease Mapping: From Foundations to Multidimensional Modeling

1st Edition

Miguel A. Martinez-Beneito, Paloma Botella-Rocamora
July 17, 2019

Disease Mapping: From Foundations to Multidimensional Modeling guides the reader from the basics of disease mapping to the most advanced topics in this field. A multidimensional framework is offered that makes possible the joint modeling of several risks patterns corresponding to combinations of...

Nonlinear Estimation: Methods and Applications with Deterministic Sample Points

1st Edition

Shovan Bhaumik, Paresh Date
July 17, 2019

Nonlinear Estimation: Methods and Applications with Deterministic Sample Points focusses on a comprehensive treatment of deterministic sample point filters (also called Gaussian filters) and their variants for nonlinear estimation problems, for which no closed-form solution is available in general....

Mathematical and Statistical Skills in the Biopharmaceutical Industry: A Pragmatic Approach

1st Edition

Arkadiy Pitman, Oleksandr Sverdlov, L. Bruce Pearce
July 16, 2019

Mathematical and Statistical Skills in the Biopharmaceutical Industry: A Pragmatic Approach describes a philosophy of efficient problem solving showcased using examples pertinent to the biostatistics function in clinical drug development. It was written to share a quintessence of the authors’...

Dose-Response Analysis Using R

1st Edition

Christian Ritz, Signe Marie Jensen, Daniel Gerhard, Jens Carl Streibig
July 11, 2019

Nowadays the term dose-response is used in many different contexts and many different scientific disciplines including agriculture, biochemistry, chemistry, environmental sciences, genetics, pharmacology, plant sciences, toxicology, and zoology. In the 1940 and 1950s, dose-response analysis was...

Bayesian Analysis with R for Drug Development: Concepts, Algorithms, and Case Studies

1st Edition

Harry Yang, Steven Novick
July 11, 2019

Drug development is an iterative process. The recent publications of regulatory guidelines further entail a lifecycle approach. Blending data from disparate sources, the Bayesian approach provides a flexible framework for drug development. Despite its advantages, the uptake of Bayesian...

Metamodeling for Variable Annuities

1st Edition

Guojun Gan, Emiliano A. Valdez
July 11, 2019

This book is devoted to the mathematical methods of metamodeling that can be used to speed up the valuation of large portfolios of variable annuities. It is suitable for advanced undergraduate students, graduate students, and practitioners. It is the goal of this book to describe the computational...

Introduction to Statistical Decision Theory: Utility Theory and Causal Analysis

1st Edition

Silvia Bacci, Bruno Chiandotto
July 08, 2019

Introduction to Statistical Decision Theory: Utility Theory and Causal Analysis provides the theoretical background to approach decision theory from a statistical perspective. It covers both traditional approaches, in terms of value theory and expected utility theory, and recent developments, in...

Conferences

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