Biostatistics and Epidemiology

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Handbook of Quantile Regression


Roger Koenker, Victor Chernozhukov, Xuming He, Limin Peng
October 25, 2017

Quantile regression constitutes an ensemble of statistical techniques intended to estimate and draw inferences about conditional quantile functions. Median regression, as introduced in the 18th century by Boscovich and Laplace, is a special case. In contrast to conventional mean regression that mini...

Adaptive Survey Design


Barry Schouten, Andy Peytchev, James Wagner
August 4, 2017

Adaptive survey designs (ASDs) provide a framework for data-driven tailoring of data collection procedures to different sample members, often for cost and bias reduction. People vary in how likely they are to respond and in how they respond. This variation leads to opportunities to selectively deplo...

Methods in Comparative Effectiveness Research


Constantine Gatsonis, Sally C. Morton
February 7, 2017

Comparative effectiveness research (CER) is the generation and synthesis of evidence that compares the benefits and harms of alternative methods to prevent, diagnose, treat, and monitor a clinical condition or to improve the delivery of care (IOM 2009). CER is conducted to develop evidence that will...

Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials


John O'Quigley, Alexia Iasonos, Björn Bornkamp
April 26, 2017

Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials gives a thorough presentation of state-of-the-art methods for early phase clinical trials. The methodology of clinical trials has advanced greatly over the last 20 years and, arguably, nowhere greater than that of ear...

Statistics for Biotechnology Process Development

Todd Coffey, Harry Yang
June 05, 2018

Written specifically for biotechnology scientists, engineers, and quality professionals, this book describes and demonstrates the proper application of statistical methods throughout Chemistry, Manufacturing, and Controls (CMC). Filled with case studies, examples, and easy-to-follow explanations of...

Bayesian Methods for Repeated Measures

Lyle D. Broemeling
June 01, 2018

Analyze Repeated Measures Studies Using Bayesian Techniques Going beyond standard non-Bayesian books, Bayesian Methods for Repeated Measures presents the main ideas for the analysis of repeated measures and associated designs from a Bayesian viewpoint. It describes many inferential methods for...

Bayesian Disease Mapping: Hierarchical Modeling in Spatial Epidemiology, Third Edition

Andrew B. Lawson
May 24, 2018

Since the publication of the second edition, many new Bayesian tools and methods have been developed for space-time data analysis, the predictive modeling of health outcomes, and other spatial biostatistical areas. Exploring these new developments, Bayesian Disease Mapping: Hierarchical Modeling in...

Nonparametric Models for Longitudinal Data: With Implementation in R

Colin O. Wu, Xin Tian
May 15, 2018

Nonparametric Models for Longitudinal Data with Implementations in R presents a comprehensive summary of major advances in nonparametric models and smoothing methods with longitudinal data. It covers methods, theories, and applications that are particularly useful for biomedical studies in the era...

Medical Statistics: An A-Z Companion, Second Edition

Filomena Pereira-Maxwell
May 04, 2018

This invaluable, jargon-free guide to essential medical terminology in an accessible A-Z format is ideal for medical, allied health and biomedical science students and researchers, clinicians and health care practitioners. Avoiding the complex language that is so often a feature of...

Multistate Models for the Analysis of Life History Data

Richard J Cook, Jerald F. Lawless
May 04, 2018

Multistate Models for the Analysis of Life History Data provides the first comprehensive treatment of multistate modeling and analysis, including parametric, nonparametric and semiparametric methods applicable to many types of life history data. Special models such as illness-death, competing risks...

Self-Controlled Case Series Studies: A Modelling Guide with R

Paddy Farrington, Heather Whitaker, Yonas Ghebremichael Weldeselassie
May 02, 2018

Self-Controlled Case Series Studies: A Modelling Guide with R provides the first comprehensive account of the self-controlled case series (SCCS) method, a statistical technique for investigating associations between outcome events and time-varying exposures. The method only requires information...

Mathematical Theory of Bayesian Statistics

Sumio Watanabe
April 30, 2018

Mathematical Theory of Bayesian Statistics introduces the mathematical foundation of Bayesian inference which is well-known to be more accurate in many real-world problems than the maximum likelihood method. Recent research has uncovered several mathematical laws in Bayesian statistics, by which...

Modelling Interactions Between Vector-Borne Diseases and Environment Using GIS

Hassan M. Khormi, Lalit Kumar
April 30, 2018

Master GIS Applications on Modelling and Mapping the Risks of Diseases Infections transmitted by mosquitoes, ticks, triatomine bugs, sandflies, and black flies cause significant rates of death and disease, especially in developing countries. Why are certain places more susceptible to vector-borne...

Generalized Linear Models and Extensions: Fourth Edition

James W. Hardin, Joseph M. Hilbe
April 27, 2018

Generalized linear models (GLMs) extend linear regression to models with a non-Gaussian, or even discrete, response. GLM theory is predicated on the exponential family of distributions—a class so rich that it includes the commonly used logit, probit, and Poisson models. Although one can fit these...

A Practical Guide to Age-Period-Cohort Analysis: The Identification Problem and Beyond

Wenjiang Fu
April 25, 2018

Age-Period-Cohort analysis has a wide range of applications, from chronic disease incidence and mortality data in public health and epidemiology, to many social events (birth, death, marriage, etc) in social sciences and demography, and most recently investment, healthcare and pension contribution...

An Introduction to Generalized Linear Models, Fourth Edition

Annette J. Dobson, Adrian G. Barnett
April 13, 2018

An Introduction to Generalized Linear Models, Fourth Edition provides a cohesive framework for statistical modelling, with an emphasis on numerical and graphical methods. This new edition of a bestseller has been updated with new sections on non-linear associations, strategies for model selection,...