Statistics

Biostatistics and Epidemiology

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Handbook of Quantile Regression

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Roger Koenker, Victor Chernozhukov, Xuming He, Limin Peng
October 25, 2017

Quantile regression constitutes an ensemble of statistical techniques intended to estimate and draw inferences about conditional quantile functions. Median regression, as introduced in the 18th century by Boscovich and Laplace, is a special case. In contrast to conventional mean regression that mini...

Adaptive Survey Design

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Barry Schouten, Andy Peytchev, James Wagner
August 4, 2017

Adaptive survey designs (ASDs) provide a framework for data-driven tailoring of data collection procedures to different sample members, often for cost and bias reduction. People vary in how likely they are to respond and in how they respond. This variation leads to opportunities to selectively deplo...

Methods in Comparative Effectiveness Research

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Constantine Gatsonis, Sally C. Morton
February 7, 2017

Comparative effectiveness research (CER) is the generation and synthesis of evidence that compares the benefits and harms of alternative methods to prevent, diagnose, treat, and monitor a clinical condition or to improve the delivery of care (IOM 2009). CER is conducted to develop evidence that will...

Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials

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John O'Quigley, Alexia Iasonos, Björn Bornkamp
April 26, 2017

Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials gives a thorough presentation of state-of-the-art methods for early phase clinical trials. The methodology of clinical trials has advanced greatly over the last 20 years and, arguably, nowhere greater than that of ear...

Randomization, Masking, and Allocation Concealment

Vance Berger
October 27, 2017

Randomization, Masking, and Allocation Concealment is indispensable for any trial researcher who wants to use state of the art randomization methods, and also wants to be able to describe these methods correctly. Far too often the subtle nuances that distinguish proper randomization from flawed...

Handbook of Quantile Regression

Roger Koenker, Victor Chernozhukov, Xuming He, Limin Peng
October 25, 2017

Quantile regression constitutes an ensemble of statistical techniques intended to estimate and draw inferences about conditional quantile functions. Median regression, as introduced in the 18th century by Boscovich and Laplace, is a special case. In contrast to conventional mean regression that...

Nonparametric Statistical Tests: A Computational Approach

Markus Neuhauser
October 23, 2017

Nonparametric Statistical Tests: A Computational Approach describes classical nonparametric tests, as well as novel and little-known methods such as the Baumgartner-Weiss-Schindler and the Cucconi tests. The book presents SAS and R programs, allowing readers to carry out the different statistical...

Handbook of Statistics in Clinical Oncology, Third Edition

John Crowley, Antje Hoering
September 12, 2017

Many new challenges have arisen in the area of oncology clinical trials. New cancer therapies are often based on cytostatic or targeted agents, which pose new challenges in the design and analysis of all phases of trials. The literature on adaptive trial designs and early stopping has been...

Health Econometrics Using Stata

Partha Deb, Edward C. Norton, Willard G. Manning
September 08, 2017

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Absolute Risk: Methods and Applications in Clinical Management and Public Health

Ruth M. Pfeiffer, Mitchell H. Gail
August 30, 2017

Absolute Risk: Methods and Applications in Clinical Management and Public Health provides theory and examples to demonstrate the importance of absolute risk in counseling patients, devising public health strategies, and clinical management. The book provides sufficient technical detail to allow...

Sample Size Calculations in Clinical Research, Third Edition

Shein-Chung Chow, Jun Shao, Hansheng Wang, Yuliya Lokhnygina
August 30, 2017

Praise for the Second Edition: "… this is a useful, comprehensive compendium of almost every possible sample size formula. The strong organization and carefully defined formulae will aid any researcher designing a study." -Biometrics "This impressive book contains formulae for computing sample size...

Quantitative Methods for HIV/AIDS Research

Cliburn Chan, Michael G. Hudgens, Shein-Chung Chow
August 15, 2017

Quantitative Methods in HIV/AIDS Research provides a comprehensive discussion of modern statistical approaches for the analysis of HIV/AIDS data. The first section focuses on statistical issues in clinical trials and epidemiology that are unique to or particularly challenging in HIV/AIDS research;...

Adaptive Survey Design

Barry Schouten, Andy Peytchev, James Wagner
August 04, 2017

Adaptive survey designs (ASDs) provide a framework for data-driven tailoring of data collection procedures to different sample members, often for cost and bias reduction. People vary in how likely they are to respond and in how they respond. This variation leads to opportunities to selectively...

Bayesian Methods for Repeated Measures

Lyle D. Broemeling
August 01, 2017

Analyze Repeated Measures Studies Using Bayesian Techniques Going beyond standard non-Bayesian books, Bayesian Methods for Repeated Measures presents the main ideas for the analysis of repeated measures and associated designs from a Bayesian viewpoint. It describes many inferential methods for...

Statistical Analysis of Contingency Tables

Morten Fagerland, Stian Lydersen, Petter Laake
July 12, 2017

Statistical Analysis of Contingency Tables is an invaluable tool for statistical inference in contingency tables. It covers effect size estimation, confidence intervals, and hypothesis tests for the binomial and the multinomial distributions, unpaired and paired 2x2 tables, rxc tables, ordered rx2...

The Data Book: Collection and Management of Research Data

Meredith Zozus
July 12, 2017

The Data Book: Collection and Management of Research Data is the first practical book written for researchers and research team members covering how to collect and manage data for research. The book covers basic types of data and fundamentals of how data grow, move and change over time. Focusing on...

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