1st Edition
Bionanotechnology in Cancer Diagnosis and Therapy
The cancer research world is looking forward to bionanotechnology to find the best solutions for a complete cure from cancer, which is not possible with the current established treatment methods. The past decade of research on nano imaging and drug delivery in cancer has witnessed many interesting papers and reviews, but there has not been a concise resource that discusses all fields related to nano cancer research in diagnosis and drug delivery. This book fills this gap and presents the latest bionano research in cancer, focusing on nanodiagnostics and nanotherapy.
The book is organized into two sections. The section on nanodiagnostics focuses on topics such as diagnostic methods in cancer-related therapy and use of radiolabeled nanoparticles, magnetic nanoparticles, acoustically reflective nanoparticles, X-ray computed tomography, and optical nanoprobes for diagnosis. The section on nanotherapy focuses on nanomaterials in chemotherapy, magnetic nanoparticles for hyperthermia against cancer, phototherapy, nanotechnology-mediated radiation therapy, nanoparticle-mediated small-RNA deliveries for molecular therapies, and theranostics. The book will serve as the gateway to enter the beautiful and elegant field of bionanoscience, which is considered the last hope for the fight against cancer and will be a highly useful resource for the students, researchers, teachers, and curious readers working in this field or related fields.
Sindhu C. Pillai and Jayasree Nair
2. Understanding the Interaction of Nanoparticles at the Cellular Interface
Baiju G. Nair
NANODIAGNOSTICS
3. Radiolabeled Nanoparticles for Cancer Diagnosis
R. G. Aswathy and D. Sakthi Kumar
4. Magnetic Nanoparticles for Cancer Diagnosis
R. G. Aswathy and D. Sakthi Kumar
5. Acoustically Reflective Nanoparticles for Tumor Diagnosis
R. G. Aswathy and D. Sakthi Kumar
6. X-Ray Computed Tomography and Nanomaterials as Contrast Agents for Tumor Diagnosis
R. G. Aswathy and D. Sakthi Kumar
7. Optical Nanoprobes for Diagnosis
R. G. Aswathy and D. Sakthi Kumar
NANOTHERAPY
8. Nanomaterials in Chemotherapy
P. K. Hashim and Anjaneyulu Dirisala
9. Magnetic Nanoparticles for Hyperthermia against Cancer
Sivakumar Balasubramanian and Allison J. Cowin
10. Phototherapy Using Nanomaterials
Resmi A. N., Resmi V. Nair, Rekha C. R., Lakshmi V. Nair, Shaiju S. Nazeer, and Ramapurath S. Jayasree
11. Nanotechnology-Mediated Radiation Therapy
Ankita Borah and D. Sakthi Kumar
12. Role of Nanoparticles in Cancer Immunotherapy
Madhu Malinee and Alok Kumar
13. Nanoparticle-Mediated Small RNA Deliveries for Molecular Therapies
Ramasamy Paulmurugan, Uday Kumar Sukumar, and Tarik F. Massoud
14. Theranostics: A New Holistic Approach in Nanomedicine
Ankit Rochani and Sreejith Raveendran
Biography
D. Sakthi Kumar is deputy director of Bio Nano Electronics Research Centre (BNERC) and professor in the Graduate School of Interdisciplinary New Science, Toyo University, Japan. He is interested in developing bionano devices and nanodrugs to fight cancers, organs on a chip, application of artificial intelligence in the bionano field, biomaterials, scaffolds for implantations, bio/chemical/optical sensors, nanobio imaging materials, quantum dots, and solar cells. Prof. Kumar has published more than 150 peer-reviewed research articles in international journals, has edited several books and published many book chapters, and owns 8 patents. He has delivered many plenary talks, invited talks, and tutorial talks at international seminars. For his work in biopolymers, the Society of Polymer Science, Japan, honored him with the Asia Excellence Award in 2012. Prof. Kumar is also an editorial board member of Scientific Reports.
Aswathy Ravindran Girija is a research fellow at Future Industries Research Institute, University of South Australia, Australia. She holds a PhD in life science (specialization in bionano science fusion) from Toyo University, Japan. Before moving to Australia, she was working as a post-doctoral researcher at BNERC. Dr Girija’s interdisciplinary research has focused on the development and application of biocompatible nanomaterials for theragnostic (therapeutic and diagnostic) application in cancer nanotechnology. She is an enthusiastic bionano science fusion expert with postdoctoral experience and extensive hands-on skills in nanotechnology (nanomaterials synthesis and characterization), targeted drug delivery in cancer cells, imaging cancer cells with contrast agents, development of nano-nutraceuticals, biomaterials (fabrication of nanofibers by electrospinning for wound healing), and microbial technology.
