1st Edition

Biosensors An Introductory Textbook

By Jagriti Narang, C.S. Pundir Copyright 2017
    174 Pages 7 Color & 15 B/W Illustrations
    by Jenny Stanford Publishing

    174 Pages 7 Color & 15 B/W Illustrations
    by Jenny Stanford Publishing

    Nanotechnology is a budding field and has a pivotal role in sensing. Nanomaterials exist in various forms such as nanoparticles, nanoclusters, nanobelts, and nanospheres. These nanomaterials act as sensing interfaces and immobilization surfaces for various biomolecules such as enzymes, DNA, and antigens. Therefore, the preparation and characterization of these nanoparticles play an important role in sensing devices.

    This handbook has evolved from the authors’ teaching and research experience in the field of nanoparticle biosensing. It encompasses protocols for the synthesis of various forms of metal oxide nanoparticles; study of the various characterizing techniques that help deduce the shape, size, and morphology of these nanoparticles; and applications of these nanoparticles in the field of biosensors. It presents voltammetry techniques such as cyclic, linear wave, wave pulse, and differential pulse voltammetry, throws light on the interactions of nanomaterials and biomolecules, and discusses microfluidic devices, which due to their unique capability of miniaturization fascinate many researchers. It is a practical and user-friendly textbook that introduces the various basic principles and practical information that will help undergraduate and advanced-level students and researchers understand the science behind nanoscale sensing.

    Nanomaterials

    Introduction

    Occurrence of Nanomaterials

    Revolution in Nanomaterials

    Classification of Nanomaterials

    Importance of Nanomaterials

    Synthesis and Processing of Nanomaterials

    Biological/Green Synthesis of Nanoparticles

    Properties of Nanomaterials

    Conclusion and Future Perspective

    Synthesis of Individual Nanomaterials

    Introduction to Noble Metal Nanomaterials

    Parameters Affecting the Size, Dispersion, and Shape of Metal Nanoparticles

    Synthesis of Individual Metal Nanoparticles

    Conclusion

    Characterization Techniques

    Introduction

    Scanning Electron Microscopy

    Transmission Electron Microscopy

    Atomic Force Microscopy

    Scattering Methods

    Spectroscopy Methods

    Conclusion

    Fabrication of Sensors for Electrochemical Determination

    Introduction

    Enzyme-Based Electrochemical Biosensors

    DNA-Based Sensors

    Immunosensors

    Conclusion

    Electrochemical Techniques

    Introduction

    Equipment Used in Voltammetric Experiments

    Cyclic Voltammetry

    Polarogram Graph

    Square Wave Voltammetry

    Differential Pulse Voltammetry

    Conclusion

    Biosensors for Serum Metabolites

    Biosensors Based on Field Effect

    Optical Biosensors

    Piezoelectric Biosensors

    Calorimetric Biosensors

    Electrochemical Biosensors

    Applications of Biosensors for Determining Serum Metabolites

    Conclusion

    Microfluidics: A Platform for Futuristic Sensors

    Introduction

    Microfluidic Basics

    Importance of Microfluidics

    Manufacturing Methods

    Microfluidic Devices

    Fluid Flow in Microfluidic Devices

    Microchannels

    Applications of Microfluidics

    Conclusion

    Biography

    Jagriti Narang is assistant professor at Amity Institute of Nanotechnology, Amity University, Uttar Pradesh, India, and has a work experience of more than 8 years. She has authored or coauthored 57 research papers in international peer-reviewed journals and holds 7 patents on biosensors and uses of nanotechnology in molecular techniques. Her current research interest involves the development of laboratory models that can be converted into commercial monitoring devices.

    Chandra Shekhar Pundir is emeritus professor of CSIR at the Department of Biochemistry, Maharshi Dayanand University (MDU), Rohtak, India, and has more than 36 years of teaching/research experience. He received his PhD in biochemistry from G. B. Pant University of Agriculture and Technology, Pantnagar, India. Earlier, he was professor and founder head of the Biochemistry Department and Dean of the Faculty of Life Sciences, MDU. He has authored/coauthored 249 research papers in international journals and 2 books on nanotechnology and holds 7 Indian patents and 1 international (PCT) patent in the fields of enzyme technology and biosensor technology. He is a fellow of the Royal Society of Chemistry, UK. His current research areas are analytical/clinical biochemistry, enzyme technology, biosensor technology, and bionanotechnology.

    "This book epitomizes an extensive collection of the most topical studies related to nanomaterial-based biosensors contributed by highly recognized authors in the field. The fundamental concepts of nanomaterials for biomedical implementations are expounded well. This is a very interesting book for scientists seeking inspiration to carry out research in the field of biosensors."

    —Dr. Ashwani Kumar Dubey, Amity University, India