Atopic eczema is the most common and persistent dermatological condition seen in general practice. Over the last few years, advances have been made in the genetics of atopy in general, newer treatments have been introduced for topical use, and new concepts suggested in the etiology. Thus, a new text on atopic eczema is both timely and useful. Written by one of the world's most distinguished dermatologists, An Atlas of Atopic Eczema provides full coverage of this skin disorder, including new information on calcineurin inhibitors and their therapeutic options. Extensively illustrated in color, the atlas explores topics such as genetics, etiology, pathogenesis, prognosis, clinical features, differential diagnosis, relationships to other types of eczema, and treatment. The author lifts the veil of confusion and helps physicians stay on top of the challenge the increased incidence of eczemas present.
Preface
DEFINITIONS
Dermatitis versus Eczema
Atopic
Infantile Eczema
EPIDEMIOLOGY
Place of Domicile
Incidence of Atopic Eczema Related to Age
Increasing Incidence of Atopic Eczema
NATURAL HISTORY
GENETICS
Family Studies
Twin Studies
Human Lymphocyte Antigen System
Genome Screens
Maternal Effect
Summary
PATHOGENESIS
Histology
Findings in the Blood
Immunopathogenesis
Inflammatory Cells
Immunoglobulin E
Summary
ETIOLOGY
Genetics: Possible Candidate Genes
Abnormal Skin Barrier
Allergens
Aeroallergens
Autoantigens
Bacteria
Fungi
Environmental Pollution
Hygiene Hypothesis
Pharmacological and Vascular Abnormalities
Emotional Factors
Neuropeptides
Summary
CLINICAL FEATURES
Age of Onset
Sex
Clinical Features of Eczema per se
Age-related Features
Non-age-related Features
Atopic Eczema at Specific Sites
Other Eczematous Skin Disorders in Atopic Individuals
Non-eczematous Cutaneous Features of Atopy
Other Disorders Associated with Atopic Eczema
Infections
DIFFERENTIAL DIAGNOSIS
Other Eczematous Conditions
Syndromes with Eczematous Eruptions
Non-eczema Disorders
MANAGEMENT
Emollients
Bathing
Clothing
Climate
Diet
Breast-feeding
Delayed Introduction of Solid Foods
Avoidance of Food Antigens in Pregnancy
Probiotics
Aeroallergens
Animals
Psychotherapeutic Measures
Investigations
Topical Drugs
Antistaphylococcal Treatment
Antiviral Treatment
Antifungal Treatment
Ultraviolet Light
Systemic Treatment
Biological Agents
The Future
References
Index
Biography
Fry, Lionel
"In this slim but focused book, Professor Lionel Fry has captured all we need to know about eczema. …replete with diagrams, helpful reminders in illustrative form, and plenty of pictures of the many expressions of eczema. The teachings of the renowned Professor Fry are delightfully presented in both word and illustration."
-From the Foreword by Charles N. Ellis, MD, University of Michigan
