1st Edition

Airway Chemoreceptors in Vertebrates

Edited By Giacomo Zaccone, Ernest Cutz, Dirk Adriaensen Copyright 2009

    This book provides a comprehensive and up-to-date account of the information available on the morphological, physiological and evolutionary aspects of specialized cells distributed within the epithelia of the airways in the vertebrates. A lot of work has been done on the cell and molecular biology of these cells which are regarded as as oxygen receptor neuroepithelial cells. These chemoreceptors which were conserved throughout evolution have neuroendocrine functions carrying their signals to the central nervous system.

    The chemoreceptor cells are sensors which detect the signal changes in the external and internal environments, and play a key role in the survival of various species. Studies addressed to the chemoreceptor cell systems in the airways are of great importance for investigating their response to changes in the oxygen and carbon dioxide concentrations in the environment since the future of the planet earth is being threatened by global warming and climate change.

    Praise for the book:

    …This volume would be of special interest to researchers who are curious about the evolution of vertebrate respiratory control in general and the regulation of ventilation in nonmammalian vertebrates in particular. —Wayne L. Silver, Wake Forest University, in The Quarterly Review of Biology, Volume 85, Number 2

    Preface
    Neurosecretory Epithelial Cells (NEC’s) in the Airways and Carotid Labyrinth of Aquatic Vertebrates: Morphology, Distribution, Innervation and Function
    Oxygen-sensitive Neuroepithelial Cells in the Gills of Aquatic Vertebrates
    Michael G. Jonz and Colin A. Nurse
    Carotid Labyrinth and Associated PseudobranchialNeurosecretory Cells in Indian Catfishes A. Gopesh
    Serotonergic Neuroepithelial Cells in Fish Gills:Cytology and Innervation Yannick J.R. Bailly

    Neurosecretory Cells (NEC’s) in the Lung of Amphibians and Accessory Respiratory Organs of the Air-breathing Fishes and in Amphibian Carotid Labyrinth: Structural Morphology and Function
    Neuroendocrine Cells in the Lungs of Amphibians and Air-Breathing Fishes
    Lucyna Goniakowska-Witalńska, Anna Pecio and Dagmara Podkowa
    The Amphibian Carotid Labyrinth Tatsumi Kusakabe
    Neuroendocrine System of the Amphibian Extrapulmonary Airways Luis Miguel Pastor García and Esther Beltrán-Frutos
    Chemoreceptive Control of Ventilation in Amphibiansand Air-Breathing Fishes Warren Burggren and Tien-Chien Pan


    Neuroepithelial Bodies(NEB’s) in the Lung of Reptiles: Structural Morphology, Immunohistochemistry and Function
    Neuroendocrine System of the Reptilian Respiratory Tract Luis Miguel Pastor García, Giacomo Zaccone and Esther Beltrán-Frutos
    Airway Receptors in Birds M. Fabiana Kubke, Roderick A. Suthers and J. Martin Wild
    Mechanisms of CO2 Sensing in Avian Intrapulmonary Chemoreceptors Steven C. Hempleman and Jason Q. Pilarski

    Pulmonary Neuroepithelial Cells in Mammals: Structure, Molecular Markers, Ontogeny and Functions
    Diverse and Complex Airway Receptors in Rodent Lungs
    Inge Brouns, Isabel Pintelon, Ian De Proost, Jean-Pierre Timmermans and Dirk Adriaensen
    Oxygen Sensing in Mammalian Pulmonary Neuroepithelial Bodies E. Cutz, W.X. Fu, H. Yeger, J. Pan and C.A. Nurse
    Precursors and Stem Cells of the Pulmonary Neuroendocrine Cell System in the Developing Mammalian Lung H. Yeger, J. Pan and E. Cutz
    Pulmonary Neuroepithelial Bodies as Hypothetical Immunomodulators: Some New Findings and a Review of the Literature Alfons T.L. Van Loomel, Tania Bollé and Peter W. Hellings
    Neuroepithelial Bodies and Carotid Bodies: A Comparative Discussion of Pulmonary and Arterial Chemoreceptors Alfons T.L. Van Lommel

    Solitary Chemosensory Cells in the Airways of Mammals: Distribution, Immunocytochemistry, Fine Structure and Function

    Solitary Chemosensory Cells in the Airways of Mammals A. Sbarbati, M.P. Cecchini, C. Crescimanno, F. Merigo, D. Benati, M. Tizzano and F. Osculati
    Solitary Chemosensory Cells: Phylogeny and Ontogeny Anne Hansen and Thomas E. Finger
    Functional Importance of Pulmonary Neuroendocrine Cells Staffan Skogvall
    CO2/H+ Chemoreceptors in the Respiratory Passages of Vertebrates K.M. Gilmour and W.K. Milsom
    Index

    Biography

    Giacomo Zaccone

    This book provides a review of the chemoreceptive cells associated with vertebrate respiration. … Most of the cells described in this volume detect respiratory gases and function to help regulate ventilation. Other roles include immune system activation, defense against bacteria, and environmental chemical detection. The majority of the book looks at the anatomy of respiratory-related structures: lungs (gills), carotid labyrinths (carotid body), and respiratory passages. … There are five sections organized by vertebrate class (fish, amphibians, reptiles/birds, and two for mammals). …This volume would be of special interest to researchers who are curious about the evolution of vertebrate respiratory control in general and the regulation of ventilation in nonmammalian vertebrates in particular.
    —Wayne L. Silver, Wake Forest University, in The Quarterly Review of Biology, Volume 85, Number 2