PET and SPECT imaging has improved to such a level that they are opening up exciting new horizons in medical diagnosis and treatment. This book provides a complete introduction to fundamentals and the latest progress in the field, including an overview of new scintillator materials and innovations in photodetector development, as well as the latest system designs and image reconstruction algorithms. It begins with basics of PET and SPECT physics, followed by technology advances and computing methods, quantitative techniques, multimodality imaging, instrumentation, pre-clinical and clinical imaging applications.
Part 1 BASICS
Principles of SPECT and PET Imaging
Magnus Dahlbom and Michael A. King
Part 2 TECHNOLOGY
Scintillators for PET and SPECT
Charles L. Melcher and Lars Eriksson
Photodetectors
Magnus Dahlbom
Acquisition Electronics
Thomas K. Lewellen
SPECT Instrumentation
Wei Chang, Michael Rozler, and Scott D. Metzler
PET Instrumentation
Andrew L. Goertzen and Jonathan D. Thiessen
PART 3 QUANTITATIVE IMAGING
Methodologies for Quantitative SPECT
Irène Buvat
Data Corrections and Quantitative PET
Suleman Surti and Joshua Scheuermann
Image Reconstruction for PET and SPECT
Richard M. Leahy, Bing Bai, and Evren Asma
High-Performance Computing in Emission Tomography
Guillem Pratx
Methods and Applications of Dynamic SPECT Imaging
Anna M. Celler, Troy H. Farncombe, Alvin Ihsani, Arkadiusz Sitek, and R. Glenn Wells
Dynamic PET Imaging
Sung-Cheng (Henry) Huang and Koon-Pong Wong
Part 4 MULTIMODALITY IMAGING
PET/CT
Søren Holm, Osama Mawlawi, and Thomas Beyer
SPECT/CT
Yothin Rakvongthai, Jinsong Ouyang, and Georges El Fakhri
PET/MRI
Ciprian Catana
Part 5 PRECLINICAL IMAGING AND CLINICAL APPLICATIONS
Preclinical PET and SPECT
Steven R. Meikle, Andre Z. Kyme, Peter Kench, Frederic Boisson, and Arvind Parmar
Clinical Applications of PET/CT and SPECT/CT Imaging
Johannes Czernin and Ora Israel, Ken Herrmann, Martin Barrio, David Nathanson, and Martin Allen-Auerbach
Biography
Magnus Dahlbom has been working in the field of Nuclear Medicine for close to 30 years. He earned his B.Sc. in physics from the University of Stockholm in 1982. He received his Ph.D. from UCLA in 1987. His Ph.D. research was on high-resolution PET detectors and image processing. In 1989 he was part of the team that started the first clinical PET operation in the U.S. at UCLA. Around the same time developed together with Drs. Edward J. Hoffman and Michael E. Phelps the Whole Body PET imaging technique, which currently makes up more than 90% of all PET studies performed. His research interests are in PET and SPECT instrumentation and image processing. Since 1989 he has been the chief physicist at the Nuclear Medicine services at UCLA where he is responsible for all imaging instrumentation, including SPECT, SPECT/CT and PET/CT systems. At UCLA he is the faculty graduate advisor in the Biomedical Physics graduate program. He is teaching graduate level courses on the basics of Nuclear Medicine imaging and instrumentation. He has authored and co-authored more than 120 research papers and 11 book chapters on nuclear imaging instrumentation and processing. He was also co-editor of a PET/CT atlas. For the last 6 years he has been serving as an editorial consultant to the editor-in-chief of the Journal of Nuclear Medicine.
"A well-written, comprehensive, advanced-level book that also provides enough information about the physics, mathematics, instrumentation, quantification, and clinical applications of these imaging modalities."
-Jun Zhang, The Ohio State University
