5th Edition

Modern Pharmaceutics Volume 1 Basic Principles and Systems, Fifth Edition

Edited By Alexander T. Florence, Juergen Siepmann Copyright 2010
    652 Pages 120 B/W Illustrations
    by CRC Press

    With over 100 illustrations, Volume 1 addresses the core disciplines of pharmaceutics (absorption, PK, excipients, tablet dosage forms, and packaging), and explores the challenges and paradigms of pharmaceutics.

    Key topics in Volume 1 include:

    • principles of drug absorption, chemical kinetics, and drug stability
    • pharmacokinetics
    • the effect of route of administration and distribution on drug action
    • in vivo imaging of dose forms: gamma scintigraphy, PET imaging NMR, MRI, etc.
    • powder technology
    • excipient design and characterization
    • preformulation
    • optimization techniques in pharmaceutical formulation and processing
    • disperse and surfactant systems
    • the solid state, tablet dosage forms, coating processes, and hard and soft shell capsules
    • parenteral products

    Volume 1:

    1. Pharmaceutics: New Challenges, New Paradigms
    Alexander T. Florence and Juergen Siepmann

    2. Principles of Drug Absorption
    Michael Mayersohn

    3. Pharmacokinetics
    David W. A. Bourne

    4. Factors Influencing Oral Drug Absorption and Drug Availability
    Juergen Siepmann, Florence Siepmann, and Alexander T. Florence

    5. Effect of Route of Administration and Distribution on Drug Action
    Maureen D. Donovan

    6. In Vivo Imaging of Dosage Forms
    Zheng-Rong Lu

    7. Chemical Kinetics and Drug Stability
    David Attwood and Rolland I. Poust

    8. The Solid State
    Alastair J. Florence

    9. Excipient Design and Characterization
    Graham Buckton

    10. Preformulation
    Gavin W. Halbert

    11. Disperse Systems
    Wandee Rungseevijitprapa, Florence Siepmann, Juergen Siepmann, and Ornlaksana Paeratakul

    12. Surfactants
    David Attwood

    13. Tablet Dosage Forms
    Murat Turkoglu and Adel Sakr

    14. Hard- and Soft-Shell Capsules
    Larry L. Augsburger

    15. Parenteral Products
    James C. Boylan and Steven L. Nail

    Index

    Biography

    Juergen Siepmann, Alexander T. Florence