1st Edition

Epigenetics and Assisted Reproduction An Introductory Guide

Edited By Cristina Camprubí, Joan Blanco Copyright 2019
    214 Pages 1 Color Illustrations
    by CRC Press

    214 Pages 1 Color Illustrations
    by CRC Press

    Epigenetics is the study of how certain genes are activated without modification at the DNA sequence level, resulting in genetically similar individuals having different clinical outcomes. As contemporary medicine increasingly aims to personalize the medical approach to a patient's genetic profile, the factors that can affect which genes are expressed also increase in importance and relevance to the clinician. This text from experts will give the clinician in Reproductive Medicine a reliable grounding in current thinking and research on this fast-moving topic, with many clinical implications.

    A Short Introduction to DNA Methylation.  Epigenetic Modifications of Histones.  Epigenetic Reprogramming in Early Embryo Development.  Epigenetic Reprogramming of Mammalian Primordial Germ Cells.  Laboratory Molecular Methodologies to Analyze DNA Methylation.  Intrinsic and Extrinsic Factors That Influence Epigenetics.  Epigenetic and Assisted Reproduction Epidemiological Studies.  Epigenetics and Assisted Reproduction Experimental Studies: Sperm Epigenome.  Epigenetic and Assisted Reproduction Experimental Studies: Sperm ncRNAs.  Epigenetic and Assisted Reproduction Experimental Studies: Ovarian Stimulation.  Epigenetic and Assisted Reproduction Experimental Studies: In Vitro Culture.  Epigenetics: Hope against Genetic Determinism.  Future Perspectives.

    Biography

    Cristina Camprubí is Founder and Director of GenIntegral, a genetic and epigenetic advisory service for professionals and patients. The author of more than twenty scientific papers published in high impact factor journals, and several book chapters, she participates as teacher/speaker in many postgraduate and specialist courses such as the Dexeus Forum Update in Obstetrics, Gynaecology and Reproductive Medicine.


    Joan Blanco is Professor at the Unitat de Biologia Cellular (Facultat de Biociències), Universitat Autònoma de Barcelona, Bellaterra (Cerdanyola del Vallès), Spain.