Based on the proceedings of the International Convocation on Immunology held recently at the State University of New York at Buffalo, this up-to-date resource provides a state-of-the-art examination of blood transfusion practice and its future possibilities.
Explains the immunological effects of blood transfusion as well as its immunological and microbiological hazards and offers potential remedies!
Preface
Contributors
THE ERNEST WITEBSKY MEMORIAL LECTURE
Red but Not Dead: Not a Hapless Sac of Hemoglobin
T. J. Greenwalt
Part I: INFECTIOUS AGENTS AND THEIR REMOVAL FROM BLOOD AND BLOOD COMPONENTS
Viral Contamination of Blood Components and Approaches for Reduction of Infectivity
R. Y. Dodd
Reducing the Infectivity of Blood Components—What We Have Learned
L. I. Friedman, R. R. Stromberg, and S. J. Wagner
Photodynamic Virus Inactivation of Blood Components
H. Mohr, B. Lambrecht, and A. Selz
Leukocyte Filtration Mechanisms: Factors Influencing the Removal of Infectious Agents from Red Cell Concentrates
I. Steneker, R. N. I. Pietersz, and H. W. Reesink
Use of Leukodepletion Filters for the Removal of Bacteria
W. Dzik
Transfusion-Transmitted Cytomegalovirus Infection
R. A. Bowden
PART II: TESTING FOR INFECTIOUS AGENTS
Existing Problems in the Testing for Infectious Diseases
K. Sazama
Testing Blood Donors for HIV: Current Controversies
M. P. Busch
Hepatitis Testing
C. Bianco
Bacterial Contamination of Blood Products and the Value of Pre-transfusion Testing
M. A. Blajchman
PART III: ALLOTYPES
What Is Important on the Red Blood Cell Surface
P. Tippett
Functional Factors in the Red Cell Membrane: Interactions Between the Membrane and Its Underlying Skeleton
D. J. Anstee, N. J. Hemming, and M. J. A. Tanner
Hot Spots in the Red Cell Membrane: Molecular Aspects of Some Red Cell Antigens
G. Daniels
Blood Group Antigens as Tumor Markers, Parasitic/Bacterial/Viral Receptors, and Their Association with Immunologically Important Proteins
G. Garratty
The Role of the Lymphocyte in an Immune Response
K. Balakrishnan and L. E. Adams
Neutrophil Antigens, from Bench to Bedside
A. E. G. Kr. Von dem Borne, M. de Haas, D. Roos, C. H. E. Homburg, and C. E. van der Schoot
Anti-idiotypes to HLA and Their Role in Transplantation
E. Reed
PART IV: IMMUNOLOGICAL EFFECTS OF BLOOD TRANSFUSION
Immunologic Effects of Blood Transfusion
P. I. Tartter
Transfusion Reactions: The Changing Priorities
H. Perkins
Blood Transfusion, Blood Storage, and Immunomodulation
M. S. Mincheff and H. T. Meryman
The Tumor Growth-Promoting Effect of Allogeneic Blood Transfusions
M. A. Blajchman and J. O. Bordin
The Role of Cytokines in Hemolytic Transfusion Reactions
R. D. Davenport
The Role of Cytokines and Adhesive Molecules in Febrile Non-hemolytic Transfusion Reactions
E. L. Snyder
Neonatal Anemia: Pathophysiology and Treatment
R. G. Strauss
Quality of Platelet Concentrates
J. D. Sweeney, S. Holme, and A. Heaton
The Quality of Red Blood Cells
W. A. L. Heaton
Growth Factors and Cord Blood Stem and Progenitor Cells
H. E. Broxmeyer
The Development and Use of Oxygen-Carrying Blood Substitutes
R. A. Dracker
Novel Cellular Therapies
H. G. Klein
PART V: TRANSFUSION STRATEGIES
Transfusion Strategies: Opportunities for Improvement
J. E. Menitove
Transfusion-Associated Graft-Versus-Host Disease and the Irradiation of Blood Components
R. J. Davey
Autologous Blood Transfusion: Evaluation of an Alternative Strategy in Reducing Exposure to Allogeneic Blood Transfusion
S. Qutaishat
Hematopoietic Stem Cells: "Form – Method - Characteristics"
R. A. Dracker
Uses of Intravenous Gammaglobulin in Immune Hematologic Disease
J. B. Bussel and T. P. Szatrowski
Author Index
Subject Index
Biography
Carel J. van Oss
"
…a very good addition to the library of anyone who wishes to possess a contemporary tome at the advanced level for reference, to aid in the review or development of research projects, to benchmark one's standards of practice, or to develop a greater personal depth and breadth of knowledge in these topic.
"-Hemoglobin
