1st Edition

Advances in Clinical Trial Biostatistics

Edited By Nancy L. Geller Copyright 2003

    From aspects of early trials to complex modeling problems, Advances in Clinical Trial Biostatistics summarizes current methodologies used in the design and analysis of clinical trials. Its chapters, contributed by internationally renowned methodologists experienced in clinical trials, address topics that include Bayesian methods for phase I clinica

    Bayesian Methods for Cancer Phase I Clinical Trials. Design of Early Trials in Stem Cell Transplantation: A Hybrid Frequentist-Bayesian Approach. Design and Analysis of Therapeutic Equivalence Trials. Adaptive Two-Stage Clinical Trials. Design and Analysis of Cluster Randomization Trials. Design and Analysis of Clinical Trials with Multiple Endpoints. Subgroups and Interactions. A Class of Permutation Tests for Some Two-Sample Survival Data Problems. Bayesian Reporting of Clinical Trials. Methods Incorporating Compliance in Treatment Evaluation. Analysis of Longitudinal Data with Missingness. Statistical Issues Emerging from Clinical Trials in HIV Infection.

    Biography

    Nancy L. Geller