The book explores the role of miRNAs in the development, progression, invasion, and metastasis of diverse types of cancer. It reviews their potential for applications in cancer diagnosis, prognosis, and therapeutic targets. In addition it discusses the potential use in translational medicine. Chapters present comprehensive and expert perspectives on the roles of miRNAs in most common cancers from bench to bedside applications and are written by an international team of renowned experts in the field. This book is a landmark work providing up-to-date research on miRNAs and their important roles in cancer translational research.
Breast Cancer MicroRNAs: Signaling Networks and Clinical Applications
MicroRNAs in Breast Cancer Development
MicroRNAs Controlling Invasion and Metastasis in Breast Cancer
Endometrial Cancer and MicroRNAs
MicroRNAs in Cervical Cancer: Evidences of a miRNA de-regulation caused by HPV
MicroRNAs in Prostate Cancer
MicroRNA Deregulations in Gastric Cancer
MicroRNAs in Colorectal Cancer
MicroRNAs in Lung Cancer: From Genomics to Clinical Applications
MicroRNAs in Melanoma
MicroRNAs in Medulloblastomas
Extracellular microRNAs as Potential Biomarkers and Therapeutic Tools in Cancer
MicroRNAs as Potential Therapeutic Targets in Cancer
Regulation of microRNAs for Potential Cancer Therapeutics: The Paradigm Shift from Pathways to Perturbation of Gene Regulatory Networks
Systems and Network Biology in MicroRNA Based Personalized Medicine
Biography
César López-Camarillo, Oncogenomics and Cancer Proteomics Laboratory, Autonomous University of Mexico City, Mexico City, México
Laurence A. Marchat, Multidisciplinary Program in Biomedicine, National School of Medicine and Homeopathy-IPN, Mexico City, Mexico