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Biomolecular Thermodynamics: From Theory to Application

Douglas Barrick
September 14, 2017

"an impressive text that addresses a glaring gap in the teaching of physical chemistry, being specifically focused on biologically-relevant systems along with a practical focus…. the ample problems and tutorials throughout are much appreciated." –Tobin R. Sosnick, Professor and Chair of...

Sedimentation Velocity Analytical Ultracentrifugation: Interacting Systems

Peter Schuck, Huaying Zhao
September 13, 2017

Analytical ultracentrifugation is one of the most powerful solution techniques for the study of macromolecular interactions, to define the number and stoichiometry of complexes formed, and to measure affinities ranging from very strong to very weak and repulsive. Building on the data analysis...

Advanced Electroporation Techniques in Biology and Medicine

Andrei G. Pakhomov, Damijan Miklavcic, Marko S. Markov
September 12, 2017

A reflection of the intense study of the effects of electromagnetic fields on living tissues that has taken place during the last decades, Advanced Electroporation Techniques in Biology and Medicine summarizes most recent experimental findings and theories related to permeabilization of...

Chromatin: Structure, Dynamics, Regulation

Ralf Blossey
July 21, 2017

An invaluable resource for computational biologists and researchers from other fields seeking an introduction to the topic, Chromatin: Structure, Dynamics, Regulation offers comprehensive coverage of this dynamic interdisciplinary field, from the basics to the latest research. Computational methods...

Microdosimetry: Experimental Methods and Applications

Lennart Lindborg, Anthony Waker
July 11, 2017

Experimental microdosimetry deals with the measurement of charged particle energy deposition in tissue equivalent volumes, ranging in size from nanometres to micrometres. Microdosimetry is employed to improve our understanding of the relationship between radiation energy deposition, the resulting...

An Introduction to Physical Oncology: How Mechanistic Mathematical Modeling Can Improve Cancer Therapy Outcomes

Vittorio Cristini, Eugene Koay, Zhihui Wang
July 06, 2017

Physical oncology has the potential to revolutionize cancer research and treatment. The fundamental rationale behind this approach is that physical processes, such as transport mechanisms for drug molecules within tissue and forces exchanged by cancer cells with tissue, may play an equally...

Redox Proteins in Supercomplexes and Signalosomes

Ricardo O. Louro, Irene Diaz-Moreno
July 01, 2017

Get Insight on the Function of Supercomplexes in Biological Systems Redox Proteins in Supercomplexes and Signalosomes is one of the first books to explore the key role played by redox proteins and their interaction network in a wide range of essential cellular processes in all domains of life. The...

Cellular Analysis by Atomic Force Microscopy

Malgorzata Lekka
June 27, 2017

Despite substantial evidence showing the feasibility of Atomic Force Microscopy (AFM) to identify cells with altered elastic and adhesive properties, the use of this technique as a complementary diagnostic method remains controversial. This book is designed to be a practical textbook that teaches...

Introduction to Complexity and Complex Systems

Robert B. Northrop
June 16, 2017

The boundaries between simple and complicated, and complicated and complex system designations are fuzzy and debatable, even using quantitative measures of complexity. However, if you are a biomedical engineer, a biologist, physiologist, economist, politician, stock market speculator, or politician...

Cancer Systems Biology

Edwin Wang
June 14, 2017

The unprecedented amount of data produced with high-throughput experimentation forces biologists to employ mathematical representation and computation methods to glean meaningful information in systems-level biology. Applying this approach to the underlying molecular mechanisms of tumorigenesis,...

Chirality in Biological Nanospaces: Reactions in Active Sites

Nilashis Nandi
May 31, 2017

Chirality is widely studied and omnipresent in biological molecules. However, how the retention of enantiomeric forms persists in many life processes without racemization is still unclear, and the molecular understanding of the stringent chiral specificity in enzymatic reactions is sparse. An...

Thermostable Proteins: Structural Stability and Design

Srikanta Sen, Lennart Nilsson
May 22, 2017

Thermostable Proteins: Structural Stability and Design provides a comprehensive, updated account of the physical basis of enhanced stability of thermophilic proteins and the design of tailor-made thermostable proteins, paving the way for their possible industrial applications. This book is devoted...