Pharmaceutical Science

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Approaches to the Conformational Analysis of Biopharmaceuticals

Roger L. Lundblad
May 31, 2017

The activity of many biopharmaceutical polymers is dependent on conformation, and the next several years will see increased interest in the conformational analysis of these polymers resulting from the development of biosimilar or "follow-on" biological products. While a wide variety of approaches...

Dendrimers in Medical Science

Zahoor Ahmad Parry, Rajesh Pandey
May 24, 2017

This valuable new book offers a new perspective on dendrimers that bridges the gap between basic research and applied nanomedicine. It explores the ultimate effectiveness of dendrimers in theranostics, a promising field that combines therapeutics and diagnostics into single multifunctional...

Hydrophilic Interaction Liquid Chromatography (HILIC) and Advanced Applications

Perry G. Wang, Weixuan He
May 22, 2017

This is the first book that comprehensively and systematically describes the new technology of hydrophilic interaction liquid chromatography (HILIC). Hydrophilic interaction chromatography is a separation technique suitable for polar and hydrophilic compounds and orthogonal to reversed phase liquid...

Biopharmaceuticals in Plants: Toward the Next Century of Medicine

Kathleen Laura Hefferon
May 22, 2017

Transgenic plants present enormous potential to become one of the most cost-effective and safe systems for large-scale production of proteins for industrial, pharmaceutical, veterinary, and agricultural uses. Over the past decade, much progress has been made with respect to the development of...

A Practical Guide to Managing Clinical Trials

JoAnn Pfeiffer, Cris Wells
May 19, 2017

A Practical Guide to Managing Clinical Trials is a basic, comprehensive guide to conducting clinical trials. Designed for individuals working in research site operations, this user-friendly reference guides the reader through each step of the clinical trial process from site selection, to site...

Clinical Trial Data Analysis Using R and SAS, Second Edition

Ding-Geng (Din) Chen, Karl E. Peace, Pinggao Zhang
May 03, 2017

Review of the First Edition "The goal of this book, as stated by the authors, is to fill the knowledge gap that exists between developed statistical methods and the applications of these methods. Overall, this book achieves the goal successfully and does a nice job. I would highly recommend it …The...

In Vitro Bioassay Techniques for Anticancer Drug Discovery and Development

Dhanya Sunil, Pooja R Kamath, Raghu Chandrashekhar H
May 01, 2017

This comprehensive and useful handbook represents a definitive up-to-date compendium of key in vitro bioassay methods that are employed to quantify and validate the anticancer activity of a drug candidate before it makes its way in to animal or clinical trials. In Vitro Bioassay Techniques for...

Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials

John O'Quigley, Alexia Iasonos, Björn Bornkamp
April 26, 2017

Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials gives a thorough presentation of state-of-the-art methods for early phase clinical trials. The methodology of clinical trials has advanced greatly over the last 20 years and, arguably, nowhere greater than that of...

Fundamentals of Biofilm Research, Second Edition

Zbigniew Lewandowski, Haluk Beyenal
March 31, 2017

The six years that have passed since the publication of the first edition have brought significant advances in both biofilm research and biofilm engineering, which have matured to the extent that biofilm-based technologies are now being designed and implemented. As a result, many chapters have been...

Disposable Bioprocessing Systems

Sarfaraz K. Niazi
March 29, 2017

Because of many misconceptions, the biological drug manufacturing industry does not fully utilize disposable components, despite their wide availability. These misconceptions include concerns for the quality of materials, running costs, scalability, the level of automation possible, and the...

Batch Processing: Modeling and Design

Urmila Diwekar
March 29, 2017

Although batch processing has existed for a long time, designing these processes and unit operations has been considered an onerous task that required computational efforts. Design of these processes is made more complex because of the time dependent nature of the process and the allowable...

Nanomedicine in Drug Delivery

Arun Kumar, Heidi M. Mansour, Adam Friedman, Eric R. Blough
March 29, 2017

There is a clear need for innovative technologies to improve the delivery of therapeutic and diagnostic agents in the body. Recent breakthroughs in nanomedicine are now making it possible to deliver drugs and therapeutic proteins to local areas of disease or tumors to maximize clinical benefit...