Pharmaceutical Science

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Biomedical Application of Nanoparticles

Bertrand Henri Rihn
September 06, 2017

Biomedical Application of Nanoparticles explores nanoparticles, their chemical and physicals properties, and how they interact in biological systems with proteins, immune system and targeted cells. Risk assessment of nanoparticles for human is described, including: cellular paradigms,...

Principles of Animal Extrapolation (1991)

Edward J. Calabrese
August 31, 2017

Principles of Animal Extrapolation addresses the conceptual basis for animal extrapolation and provides an abundance of documentation that illustrates how these principles may be applied in the selection of the more appropriate models and in the interpretation of toxicological studies. The book...

Respiratory Drug Delivery (1989)

Peter R. Byron
August 31, 2017

The focus of this book is on subjects related to drug delivery to the lung. The text spans topics from aerosol deposition through pharmaceutical chemistry and formulation to the final clinical evaluation of pharmaceutical products. Utilizing a multi-disciplinary approach, the chapters consider...

Sterilization Validation and Routine Operation Handbook (2001): Radiation

Anne F Booth
August 31, 2017

The validation and radiation sterilization process for biomaterials and medical devices requires careful planning to ensure regulatory compliance followed by precise accuracy in execution and documentation. This in-depth guide details all steps from prevalidation planning to final report and...

Sample Size Calculations in Clinical Research, Third Edition

Shein-Chung Chow, Jun Shao, Hansheng Wang, Yuliya Lokhnygina
August 30, 2017

Praise for the Second Edition: "… this is a useful, comprehensive compendium of almost every possible sample size formula. The strong organization and carefully defined formulae will aid any researcher designing a study." -Biometrics "This impressive book contains formulae for computing sample size...

Multicomponent Reactions: Synthesis of Bioactive Heterocycles

K.L. Ameta, Ph.D., Anshu Dandia
August 16, 2017

This timely book provides a succinct summary of methods for the synthesis of bioactive heterocycles using a multicomponent reaction (MCR) approach. The majority of pharmaceuticals and biologically active agrochemicals are heterocycles while countless additives and modifiers used in industrial...

Functional Hydrogels in Drug Delivery: Key Features and Future Perspectives

Umile Gianfranco Spizzirri, Giuseppe Cirillo
August 16, 2017

The book deals with the synthesis and characterization of hydrogels specifically used as drug delivery systems. Each chapter includes the most recent updates about the different starting materials employed and the improvement of their physicochemical and biological properties to synthetize high...

Nonclinical Drug Administration: Formulations, Routes and Regimens for Solving Drug Delivery Problems in Animal Model Systems

Shayne C. Gad, Charles B. Spainhour
August 15, 2017

The concept of the perfect medicine as a molecule that goes with high selectivity to the therapeutic target site, does what it needs to do, and is subsequently cleared from the body is especially relevant now. Much of the current costs and post-market safety concerns arise from the inability to...

Capillary Electrophoresis: Trends and Developments in Pharmaceutical Research

Suvardhan Kanchi, Salvador Sagrado, Myalo I. Sabela, Krishna Bisetty
August 10, 2017

Capillary electrophoresis (CE) has become an established method with widespread recognition as an analytical technique of choice in numerous analytical laboratories, including industrial and academic sectors. Pharmaceutical and biochemical research and quality control are the most important CE...

Advances in Chromatography: Volume 54

Nelu Grinberg, Eli Grushka
August 10, 2017

For more than five decades, scientists and researchers have relied on the Advances in Chromatography series for the most up-to-date information on a wide range of developments in chromatographic methods and applications. For Volume 54, the series editors have invited established, well-known...

CRC Handbook of Sample Size Guidelines for Clinical Trials

Jonathan J. Shuster
July 27, 2017

The aim of this unique volume is to help medical researchers design clinical trials to improve survival, remission duration, or time to recurrence of disease. Written in a user-friendly step-by-step format, this work enables the researcher-with no background in statistics-to determine sample size...

In Silico Drug Discovery and Design: Theory, Methods, Challenges, and Applications

Claudio N. Cavasotto
July 26, 2017

In Silico Drug Discovery and Design: Theory, Methods, Challenges, and Applications provides a comprehensive, unified, and in-depth overview of the current methodological strategies in computer-aided drug discovery and design. Its main aims are to introduce the theoretical framework and algorithms,...