Pharmaceutical Science

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Multicomponent Reactions: Synthesis of Bioactive Heterocycles

K.L. Ameta, Ph.D., Anshu Dandia
August 16, 2017

This timely book provides a succinct summary of methods for the synthesis of bioactive heterocycles using a multicomponent reaction (MCR) approach. The majority of pharmaceuticals and biologically active agrochemicals are heterocycles while countless additives and modifiers used in industrial...

Functional Hydrogels in Drug Delivery: Key Features and Future Perspectives

Umile Gianfranco Spizzirri, Giuseppe Cirillo
August 16, 2017

The book deals with the synthesis and characterization of hydrogels specifically used as drug delivery systems. Each chapter includes the most recent updates about the different starting materials employed and the improvement of their physicochemical and biological properties to synthetize high...

Nonclinical Drug Administration: Formulations, Routes and Regimens for Solving Drug Delivery Problems in Animal Model Systems

Shayne C. Gad, Charles B. Spainhour
August 15, 2017

The concept of the perfect medicine as a molecule that goes with high selectivity to the therapeutic target site, does what it needs to do, and is subsequently cleared from the body is especially relevant now. Much of the current costs and post-market safety concerns arise from the inability to...

Capillary Electrophoresis: Trends and Developments in Pharmaceutical Research

Suvardhan Kanchi, Salvador Sagrado, Myalo I. Sabela, Krishna Bisetty
August 10, 2017

Capillary electrophoresis (CE) has become an established method with widespread recognition as an analytical technique of choice in numerous analytical laboratories, including industrial and academic sectors. Pharmaceutical and biochemical research and quality control are the most important CE...

Advances in Chromatography: Volume 54

Nelu Grinberg, Eli Grushka
August 10, 2017

For more than five decades, scientists and researchers have relied on the Advances in Chromatography series for the most up-to-date information on a wide range of developments in chromatographic methods and applications. For Volume 54, the series editors have invited established, well-known...

CRC Handbook of Sample Size Guidelines for Clinical Trials

Jonathan J. Shuster
July 27, 2017

The aim of this unique volume is to help medical researchers design clinical trials to improve survival, remission duration, or time to recurrence of disease. Written in a user-friendly step-by-step format, this work enables the researcher-with no background in statistics-to determine sample size...

In Silico Drug Discovery and Design: Theory, Methods, Challenges, and Applications

Claudio N. Cavasotto
July 26, 2017

In Silico Drug Discovery and Design: Theory, Methods, Challenges, and Applications provides a comprehensive, unified, and in-depth overview of the current methodological strategies in computer-aided drug discovery and design. Its main aims are to introduce the theoretical framework and algorithms,...

Fundamentals of Modern Bioprocessing

Sarfaraz K. Niazi, Justin L. Brown
July 26, 2017

Biological drug and vaccine manufacturing has quickly become one of the highest-value fields of bioprocess engineering, and many bioprocess engineers are now finding job opportunities that have traditionally gone to chemical engineers. Fundamentals of Modern Bioprocessing addresses this growing...

Targeted Delivery of Small and Macromolecular Drugs

Ajit S. Narang, Ram I. Mahato
July 26, 2017

Site-specific drug delivery and targeting attracts much research interest from both academia and industry, but because of the many challenges faced in the development of these systems, only a handful of targeted therapies have successfully made it into clinical practice. Focusing on the delivery...

New Generation Vaccines, Fourth Edition

Myrone M. Levine, Myron M. Levine, Gordon Dougan, Michael F. Good, Margaret A. Liu, Gary J. Nabel, James P. Nataro, Rino Rappuoli
July 13, 2017

Highlighting the latest activities and initiatives of prominent organizations working in the vaccine industry such as the Bill and Melinda Gates Foundation, The Global Alliance for Vaccines and Immunization, WHO, UNICEF, the World Bank, New Generation Vaccines, Fourth Edition, details steps...

Delivery Strategies for Antisense Oligonucleotide Therapeutics

Saghir Akhtar
July 13, 2017

With contributions from leading experts, this book is the first to focus solely on addressing the problems and reviewing the strategies currently being used to improve the delivery of antisense nucleic acids. Important delivery issues, such as improving biological stability, improving cell-specific...

Drug Delivery: An Integrated Clinical and Engineering Approach

Yitzhak Rosen, Pablo Gurman, Noel Elman
July 07, 2017

Integrating the clinical and engineering aspects of drug delivery, this book offers a much needed comprehensive overview and patient-oriented approach for enhanced drug delivery optimization and advancement. Starting with an introduction to the subject and pharmacokinetics, it explores advances for...