Pharmaceutical Science

Drug Discovery

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The Inhibitor Index: A Desk Reference on Enzyme Inhibitors, Receptor Antagonists, Drugs, Toxins, Poisons, Biologics, and Therapeutic Leads

1st Edition

Featured

Daniel Purich
June 12, 2017

Metabolic inhibitors and receptor antagonists are indispensable tools for the molecular life scientist. By blocking specific enzymes or receptor-mediated signal transduction cascades, they simplify the analysis of complex cellular processes especially when it is essential to demonstrate that a proce...

Asymmetric Synthesis of Drugs and Natural Products

1st Edition

Ahindra Nag
January 26, 2018

This book focuses on different techniques of asymmetric synthesis of important compounds, such as drugs and natural products. It gives insightful information on recent asymmetric synthesis by Inorganic, Organic and Enzymatic combinations. It also emphasizes chiral compounds and design of new...

Computational Design of Chemicals for the Control of Mosquitoes and Their Diseases

1st Edition

James Devillers
January 04, 2018

There is a compelling need for new drugs and efficient treatments against mosquito-borne diseases. Environmentally safe, but effective insecticides that address the problems of resistance are required. Computational Design of Chemicals for the Control of Mosquitoes and Their Diseases explains how...

Advances in Chromatography: Volume 55

1st Edition

Nelu Grinberg, Peter W. Carr
December 18, 2017

For more than five decades, scientists and researchers have relied on the Advances in Chromatography series for the most up-to-date information on a wide range of developments in chromatographic methods and applications. For Volume 55, established, well-known chemists offer cutting-edge reviews of...

Phage Display In Biotechnology and Drug Discovery

2nd Edition

Sachdev S. Sidhu, Clarence Ronald Geyer
November 22, 2017

Phage Display in Biotechnology and Drug Discovery, Second Edition provides a comprehensive view of the impact and promise of phage display in drug discovery and biotechnology. Building on the success of its previous edition, the book discusses current theories, principles, and methods in the field...

Neurobiology of Huntington’s Disease: Applications to Drug Discovery

1st Edition

Donald C. Lo, Robert E. Hughes
November 15, 2017

In 1993, the genetic mutation responsible for Huntington’s disease (HD) was identified. Considered a milestone in human genomics, this discovery has led to nearly two decades of remarkable progress that has greatly increased our knowledge of HD, and documented an unexpectedly large and diverse...

Handbook of Research on Medicinal Chemistry: Innovations and Methodologies

1st Edition

Debarshi Kar Mahapatra, Sanjay Kumar Bharti
November 14, 2017

This valuable new book, Handbook of Research on Medicinal Chemistry: Innovations and Methodologies, presents some of the latest advancements in the various fields of combinatorial chemistry, drug discovery, biochemical aspects, pharmacology of medicinal agents, current practical problems, and...

Multicomponent Reactions: Synthesis of Bioactive Heterocycles

1st Edition

K.L. Ameta, Ph.D., Anshu Dandia
August 16, 2017

This timely book provides a succinct summary of methods for the synthesis of bioactive heterocycles using a multicomponent reaction (MCR) approach. The majority of pharmaceuticals and biologically active agrochemicals are heterocycles while countless additives and modifiers used in industrial...

Nonclinical Drug Administration: Formulations, Routes and Regimens for Solving Drug Delivery Problems in Animal Model Systems

1st Edition

Shayne C. Gad, Charles B. Spainhour
August 15, 2017

If we will ever achieve Paul Ehrlich’s "magic bullet," that is, a molecule which goes with high selectivity to the therapeutic target site, does what it needs to do, and is subsequently cleared from the body, the practice of safety assessment will have to change. Nonclinical Drug Administration:...

Advances in Chromatography: Volume 54

1st Edition

Nelu Grinberg, Eli Grushka
August 10, 2017

For more than five decades, scientists and researchers have relied on the Advances in Chromatography series for the most up-to-date information on a wide range of developments in chromatographic methods and applications. For Volume 54, the series editors have invited established, well-known...

In Silico Drug Discovery and Design: Theory, Methods, Challenges, and Applications

1st Edition

Claudio N. Cavasotto
July 26, 2017

In Silico Drug Discovery and Design: Theory, Methods, Challenges, and Applications provides a comprehensive, unified, and in-depth overview of the current methodological strategies in computer-aided drug discovery and design. Its main aims are to introduce the theoretical framework and algorithms,...

The Inhibitor Index: A Desk Reference on Enzyme Inhibitors, Receptor Antagonists, Drugs, Toxins, Poisons, Biologics, and Therapeutic Leads

1st Edition

Daniel Purich
June 12, 2017

Metabolic inhibitors and receptor antagonists are indispensable tools for the molecular life scientist. By blocking specific enzymes or receptor-mediated signal transduction cascades, they simplify the analysis of complex cellular processes especially when it is essential to demonstrate that a...

Hydrophilic Interaction Liquid Chromatography (HILIC) and Advanced Applications

1st Edition

Perry G. Wang, Weixuan He
May 22, 2017

This is the first book that comprehensively and systematically describes the new technology of hydrophilic interaction liquid chromatography (HILIC). Hydrophilic interaction chromatography is a separation technique suitable for polar and hydrophilic compounds and orthogonal to reversed phase liquid...

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