Pharmaceutical Science

Drug Discovery

Per Page:
Sort:

The Inhibitor Index: A Desk Reference on Enzyme Inhibitors, Receptor Antagonists, Drugs, Toxins, Poisons, Biologics, and Therapeutic Leads

Featured

Daniel Purich
June 12, 2017

Metabolic inhibitors and receptor antagonists are indispensable tools for the molecular life scientist. By blocking specific enzymes or receptor-mediated signal transduction cascades, they simplify the analysis of complex cellular processes especially when it is essential to demonstrate that a proce...

Phage Display In Biotechnology and Drug Discovery, Second Edition

Sachdev S. Sidhu, Clarence Ronald Geyer
November 22, 2017

Phage Display in Biotechnology and Drug Discovery, Second Edition provides a comprehensive view of the impact and promise of phage display in drug discovery and biotechnology. Building on the success of its previous edition, the book discusses current theories, principles, and methods in the field...

Neurobiology of Huntington’s Disease: Applications to Drug Discovery

Donald C. Lo, Robert E. Hughes
November 15, 2017

In 1993, the genetic mutation responsible for Huntington’s disease (HD) was identified. Considered a milestone in human genomics, this discovery has led to nearly two decades of remarkable progress that has greatly increased our knowledge of HD, and documented an unexpectedly large and diverse...

Handbook of Research on Medicinal Chemistry: Innovations and Methodologies

Debarshi Kar Mahapatra, Sanjay Kumar Bharti
November 14, 2017

This valuable new book, Handbook of Research on Medicinal Chemistry: Innovations and Methodologies, presents some of the latest advancements in the various fields of combinatorial chemistry, drug discovery, biochemical aspects, pharmacology of medicinal agents, current practical problems, and...

Multicomponent Reactions: Synthesis of Bioactive Heterocycles

K.L. Ameta, Ph.D., Anshu Dandia
August 16, 2017

This timely book provides a succinct summary of methods for the synthesis of bioactive heterocycles using a multicomponent reaction (MCR) approach. The majority of pharmaceuticals and biologically active agrochemicals are heterocycles while countless additives and modifiers used in industrial...

Nonclinical Drug Administration: Formulations, Routes and Regimens for Solving Drug Delivery Problems in Animal Model Systems

Shayne C. Gad, Charles B. Spainhour
August 15, 2017

The concept of the perfect medicine as a molecule that goes with high selectivity to the therapeutic target site, does what it needs to do, and is subsequently cleared from the body is especially relevant now. Much of the current costs and post-market safety concerns arise from the inability to...

Advances in Chromatography: Volume 54

Nelu Grinberg, Eli Grushka
August 10, 2017

For more than five decades, scientists and researchers have relied on the Advances in Chromatography series for the most up-to-date information on a wide range of developments in chromatographic methods and applications. For Volume 54, the series editors have invited established, well-known...

In Silico Drug Discovery and Design: Theory, Methods, Challenges, and Applications

Claudio N. Cavasotto
July 26, 2017

In Silico Drug Discovery and Design: Theory, Methods, Challenges, and Applications provides a comprehensive, unified, and in-depth overview of the current methodological strategies in computer-aided drug discovery and design. Its main aims are to introduce the theoretical framework and algorithms,...

The Inhibitor Index: A Desk Reference on Enzyme Inhibitors, Receptor Antagonists, Drugs, Toxins, Poisons, Biologics, and Therapeutic Leads

Daniel Purich
June 12, 2017

Metabolic inhibitors and receptor antagonists are indispensable tools for the molecular life scientist. By blocking specific enzymes or receptor-mediated signal transduction cascades, they simplify the analysis of complex cellular processes especially when it is essential to demonstrate that a...

Hydrophilic Interaction Liquid Chromatography (HILIC) and Advanced Applications

Perry G. Wang, Weixuan He
May 22, 2017

This is the first book that comprehensively and systematically describes the new technology of hydrophilic interaction liquid chromatography (HILIC). Hydrophilic interaction chromatography is a separation technique suitable for polar and hydrophilic compounds and orthogonal to reversed phase liquid...

A Practical Guide to Managing Clinical Trials

JoAnn Pfeiffer, Cris Wells
May 19, 2017

A Practical Guide to Managing Clinical Trials is a basic, comprehensive guide to conducting clinical trials. Designed for individuals working in research site operations, this user-friendly reference guides the reader through each step of the clinical trial process from site selection, to site...

In Vitro Bioassay Techniques for Anticancer Drug Discovery and Development

Dhanya Sunil, Pooja R Kamath, Raghu Chandrashekhar H
May 01, 2017

This comprehensive and useful handbook represents a definitive up-to-date compendium of key in vitro bioassay methods that are employed to quantify and validate the anticancer activity of a drug candidate before it makes its way in to animal or clinical trials. In Vitro Bioassay Techniques for...

Imaging in Photodynamic Therapy

Michael R. Hamblin, Yingying Huang
February 01, 2017

This book covers the broad field of cellular, molecular, preclinical, and clinical imaging either associated with or combined with photodynamic therapy (PDT). It showcases how this approach is used clinically for cancer, infections, and diseases characterized by unwanted tissue such as...

Conferences

Year: