Pharmaceutical Science

Drug Development

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Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials

1st Edition

John O'Quigley, Alexia Iasonos, Björn Bornkamp
June 18, 2019

Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials gives a thorough presentation of state-of-the-art methods for early phase clinical trials. The methodology of clinical trials has advanced greatly over the last 20 years and, arguably, nowhere greater than that of...

Handbook of Drug Metabolism, Third Edition

3rd Edition

Paul G. Pearson, Larry C. Wienkers
May 21, 2019

This book continues to be the definitive reference on drug metabolism with an emphasis on new scientific and regulatory developments. It has been updated based on developments that have occurred in the last 5 years, with new chapters on large molecules disposition, stereo-selectivity in drug...

Cosmetic Formulation: Principles and Practice

1st Edition

Heather A.E. Benson, Michael S. Roberts, Vania Rodrigues Leite-Silva, Kenneth Walters
April 19, 2019

Cosmetics are the most widely applied products to the skin and include creams, lotions, gels and sprays. Their formulation, design and manufacturing ranges from large cosmetic houses to small private companies. This book covers the current science in the formulations of cosmetics applied to the...

Handbook of Preformulation: Chemical, Biological, and Botanical Drugs, Second Edition

2nd Edition

Sarfaraz K. Niazi
April 15, 2019

Preformulation studies are the physical, chemical, and biological studies needed to characterize a drug substance for enabling the proper design of a drug product, whereas the effectiveness of a drug product is determined during the formulation studies phase. Though the two disciplines overlap in...

Revival: Delivery Strategies for Antisense Oligonucleotide Therapeutics (1995)

1st Edition

Saghir Akhtar
February 20, 2019

With contributions from leading experts, this book is the first to focus solely on addressing the problems and reviewing the strategies currently being used to improve the delivery of antisense nucleic acids. Important delivery issues, such as improving biological stability, improving cell-specific...

Medicinal Chemistry with Pharmaceutical Product Development

1st Edition

Debarshi Kar Mahapatra, Sanjay Kumar Bharti
February 01, 2019

This volume focuses on novel therapeutics and strategies for the development of pharmaceutical products, keeping the drug molecule as the central component. It discusses current theoretical and practical aspects of pharmaceuticals for the discovery and development of novel therapeutics for health...

Revival: Principles of Animal Extrapolation (1991)

1st Edition

Edward J. Calabrese
January 29, 2019

Principles of Animal Extrapolation addresses the conceptual basis for animal extrapolation and provides an abundance of documentation that illustrates how these principles may be applied in the selection of the more appropriate models and in the interpretation of toxicological studies. The book...

Statistical Approaches in Oncology Clinical Development: Current Paradigm and Methodological Advancement

1st Edition

Satrajit Roychoudhury, Soumi Lahiri
November 21, 2018

Statistical Approaches in Oncology Clinical Development : Current Paradigm and Methodological Advancement presents an overview of statistical considerations in oncology clinical trials, both early and late phase of development. It illustrates how novel statistical methods can enrich the design and...

Platform Trial Designs in Drug Development: Umbrella Trials and Basket Trials

1st Edition

Zoran Antonijevic, Robert A. Beckman
November 21, 2018

Platform trials test multiple therapies in one indication, one therapy for multiple indications, or both. These novel clinical trial designs can dramatically increase the cost-effectiveness of drug development, leading to life-altering medicines for people suffering from serious illnesses, possibly...

Monte Carlo Simulation for the Pharmaceutical Industry: Concepts, Algorithms, and Case Studies

1st Edition

Mark Chang
October 25, 2018

Helping you become a creative, logical thinker and skillful "simulator," Monte Carlo Simulation for the Pharmaceutical Industry: Concepts, Algorithms, and Case Studies provides broad coverage of the entire drug development process, from drug discovery to preclinical and clinical trial aspects to...

Nanodispersions for Drug Delivery

1st Edition

Raj K. Keservani, Anil K. Sharma
October 02, 2018

This volume addresses efforts to overcome the shortcomings of conventional dosage forms by exploiting the principles of nanoscience to deliver drugs for medical treatment. Nanodispersions are an important aspect because they possess globules/particles in sizes usually below 1000 nm in which the...

Rational Basis for Clinical Translation in Stroke Therapy

1st Edition

Giuseppe Micieli, Diana Amantea
September 18, 2018

Stroke remains one of the major causes of death and long-term disability worldwide. Currently, the only approved therapy for the acute treatment of this disease is thrombolysis, a strategy that can only be applied to a small percentage of patients due to its narrow therapeutic window. Unfortunately...

Conferences

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