Pharmaceutical Science

Drug Delivery

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Dermatokinetics of Therapeutic Agents

S. Narasimha Murthy
September 12, 2017

Novel drug delivery technologies strive to bypass challenging biological layers to elicit desired pharmacological activity. The skin, one of our key defensive barriers, allows certain topically applied substances and toxins to pass. The dermatokinetics of a drug determines the efficacy of...

Biomedical Application of Nanoparticles

Bertrand Henri Rihn
September 06, 2017

Biomedical Application of Nanoparticles explores nanoparticles, their chemical and physicals properties, and how they interact in biological systems with proteins, immune system and targeted cells. Risk assessment of nanoparticles for human is described, including: cellular paradigms,...

Functional Hydrogels in Drug Delivery: Key Features and Future Perspectives

Umile Gianfranco Spizzirri, Giuseppe Cirillo
August 16, 2017

The book deals with the synthesis and characterization of hydrogels specifically used as drug delivery systems. Each chapter includes the most recent updates about the different starting materials employed and the improvement of their physicochemical and biological properties to synthetize high...

Nonclinical Drug Administration: Formulations, Routes and Regimens for Solving Drug Delivery Problems in Animal Model Systems

Shayne C. Gad, Charles B. Spainhour
August 15, 2017

The concept of the perfect medicine as a molecule that goes with high selectivity to the therapeutic target site, does what it needs to do, and is subsequently cleared from the body is especially relevant now. Much of the current costs and post-market safety concerns arise from the inability to...

Targeted Delivery of Small and Macromolecular Drugs

Ajit S. Narang, Ram I. Mahato
July 26, 2017

Site-specific drug delivery and targeting attracts much research interest from both academia and industry, but because of the many challenges faced in the development of these systems, only a handful of targeted therapies have successfully made it into clinical practice. Focusing on the delivery...

Drug Delivery: An Integrated Clinical and Engineering Approach

Yitzhak Rosen, Pablo Gurman, Noel Elman
July 07, 2017

Integrating the clinical and engineering aspects of drug delivery, this book offers a much needed comprehensive overview and patient-oriented approach for enhanced drug delivery optimization and advancement. Starting with an introduction to the subject and pharmacokinetics, it explores advances for...

Advances in Chromatographic Techniques for Therapeutic Drug Monitoring

Amitava Dasgupta
June 16, 2017

For drugs with a narrow therapeutic index, therapeutic drug monitoring methods are essential for patient management. Although immunoassays are commercially available for many drugs and most laboratories use these assays for routine therapeutic monitoring, they have many limitations which hinder...

Dendrimers in Medical Science

Zahoor Ahmad Parry, Rajesh Pandey
May 24, 2017

This valuable new book offers a new perspective on dendrimers that bridges the gap between basic research and applied nanomedicine. It explores the ultimate effectiveness of dendrimers in theranostics, a promising field that combines therapeutics and diagnostics into single multifunctional...

Nanomedicine in Drug Delivery

Arun Kumar, Heidi M. Mansour, Adam Friedman, Eric R. Blough
March 29, 2017

There is a clear need for innovative technologies to improve the delivery of therapeutic and diagnostic agents in the body. Recent breakthroughs in nanomedicine are now making it possible to deliver drugs and therapeutic proteins to local areas of disease or tumors to maximize clinical benefit...

Introduction to Market Access for Pharmaceuticals

Mondher Toumi
January 04, 2017

Market access is the fourth hurdle in the drug development process and the primary driver for global income of any new drug. Without a strategy in place for pricing, showing value for effectiveness and an understanding of the target purchasers’ needs, the drug will fail to reach its intended market...

Advances in Pulmonary Drug Delivery

Philip Chi Lip Kwok, Hak-Kim Chan
December 20, 2016

The respiratory tract has been used to deliver biologically active chemicals into the human body for centuries. However, the lungs are complex in their anatomy and physiology, which poses challenges to drug delivery. Inhaled formulations are generally more sophisticated than those for oral and...

Colloids in Drug Delivery

Monzer Fanun
November 16, 2016

Colloidal drug delivery systems present a range of therapeutic benefits in the treatment of a number of challenging conditions, allowing researchers to cross barriers that have previously prevented efficient treatment while offering improved and more targeted absorption. Summarizing recent research...