Pharmaceutical Science

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The Inhibitor Index: A Desk Reference on Enzyme Inhibitors, Receptor Antagonists, Drugs, Toxins, Poisons, Biologics, and Therapeutic Leads

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Daniel Purich
June 12, 2017

Metabolic inhibitors and receptor antagonists are indispensable tools for the molecular life scientist. By blocking specific enzymes or receptor-mediated signal transduction cascades, they simplify the analysis of complex cellular processes especially when it is essential to demonstrate that a proce...

Drug Delivery Approaches and Nanosystems, Volume 1: Novel Drug Carriers

Raj K. Keservani, Anil K. Sharma, Rajesh K. Kesharwani
September 15, 2017

Drug Delivery Approaches and Nanosystems, Volume 1: Novel Drug Carriers presents a full picture of the state-of-the-art research and development in drug delivery systems using nanotechnology and its applications. This volume, the first of a two-volume series, addresses the ever-expanding...

Drug Delivery Approaches and Nanosystems, Volume 2: Drug Targeting Aspects of Nanotechnology

Raj K. Keservani, Anil K. Sharma, Rajesh K. Kesharwani
September 15, 2017

Drug Delivery Approaches and Nanosystems, Volume 2: Drug Targeting Aspects of Nanotechnology is a thorough presentation of the state-of-the-art research and developments in drug delivery systems using nanotechnology and its applications. This two-volume set addresses the applications of...

Drug Delivery Approaches and Nanosystems, Two-Volume Set

Raj K. Keservani, Anil K. Sharma, Rajesh K. Kesharwani
September 15, 2017

This new two-volume set, Drug Delivery Approaches and Nanosystems, Volume 1: Novel Drug Carriers and Volume 2: Drug Targeting Aspects of Nanotechnology presents a comprehensive look at the state-of-the-art research and developments in drug delivery systems using nanotechnology and its applications....

Sedimentation Velocity Analytical Ultracentrifugation: Interacting Systems

Peter Schuck, Huaying Zhao
September 13, 2017

Analytical ultracentrifugation is one of the most powerful solution techniques for the study of macromolecular interactions, to define the number and stoichiometry of complexes formed, and to measure affinities ranging from very strong to very weak and repulsive. Building on the data analysis...

Handbook of Statistics in Clinical Oncology, Third Edition

John Crowley, Antje Hoering
September 12, 2017

Many new challenges have arisen in the area of oncology clinical trials. New cancer therapies are often based on cytostatic or targeted agents, which pose new challenges in the design and analysis of all phases of trials. The literature on adaptive trial designs and early stopping has been...

Dermatokinetics of Therapeutic Agents

S. Narasimha Murthy
September 12, 2017

Novel drug delivery technologies strive to bypass challenging biological layers to elicit desired pharmacological activity. The skin, one of our key defensive barriers, allows certain topically applied substances and toxins to pass. The dermatokinetics of a drug determines the efficacy of...

Embedding New Technologies into Society: A Regulatory, Ethical and Societal Perspective

Diana M. Bowman, Elen Stokes, Arie Rip
September 11, 2017

The embedding of any new technologies in society is challenging. The evolving state of the scientific art, often-unquantifiable risks and ill-defined developmental trajectories have the potential to hinder innovation and/or the commercial success of a technology. The are, however, a number of tools...

Cancer Vaccines: From Research to Clinical Practice

Adrian Bot, Mihail Obrocea, Francesco M. Marincola
September 11, 2017

Recent advances in immunology and biology have opened new horizons in cancer therapy, included in the expanding array of cancer treatment options, which are immunotherapies, or cancer vaccines, for both solid and blood borne cancers. Cancer Vaccines: From Research to Clinical Practice is the first...

Biomedical Application of Nanoparticles

Bertrand Henri Rihn
September 06, 2017

Biomedical Application of Nanoparticles explores nanoparticles, their chemical and physicals properties, and how they interact in biological systems with proteins, immune system and targeted cells. Risk assessment of nanoparticles for human is described, including: cellular paradigms,...

Sample Size Calculations in Clinical Research, Third Edition

Shein-Chung Chow, Jun Shao, Hansheng Wang, Yuliya Lokhnygina
August 30, 2017

Praise for the Second Edition: "… this is a useful, comprehensive compendium of almost every possible sample size formula. The strong organization and carefully defined formulae will aid any researcher designing a study." -Biometrics "This impressive book contains formulae for computing sample size...

Carrier-Mediated Dermal Delivery: Applications in the Prevention and Treatment of Skin Disorders

Andreia Ascenso, Helena Ribeiro, Sandra Simões
August 18, 2017

This book presents new approaches for skin aging and photocarcinogenesis and topical formulations based on nanocarrier systems for skin disorders. It discusses cosmeceuticals, laser, photodynamic therapy, and melatonin-based treatments as important strategies for photoaging management. Photodynamic...

Multicomponent Reactions: Synthesis of Bioactive Heterocycles

K.L. Ameta, Ph.D., Anshu Dandia
August 16, 2017

This timely book provides a succinct summary of methods for the synthesis of bioactive heterocycles using a multicomponent reaction (MCR) approach. The majority of pharmaceuticals and biologically active agrochemicals are heterocycles while countless additives and modifiers used in industrial...

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