Life Science

Lab Animal Science

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Management of Animal Care and Use Programs in Research, Education, and Testing

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Robert H. Weichbrod, Gail A. (Heidbrink) Thompson, John N. Norton
August 28, 2017

Biomedical research using animals requires administrators and managers who are knowledgeable and highly skilled. They must adapt to the complexity of rapidly-changing technologies, balance research goals with a thorough understanding of regulatory requirements and guidelines, and know how to work wi...

Nonhuman Primate Models For Human Diseases

W. Richard Dukelow
April 16, 2018

While research has enabled us to better understand the nonhuman primates, they have repaid that by repaid that by providing medical scientists with important tools for the study of human biomedical problems. This book is about those research tools. The book was designed by identifying areas of...

An Atlas for Staging Mammalian and Chick Embryos

H. Butler
April 16, 2018

For the convenience of research workers, particularly those with limited knowledge of embryology, we have put together a series of tables to enable rapid identification of specific stages of embryonic development in the more commonly used mammals. Because if its frequent usage the chick embryo is...

Comparative Anatomy of the Mouse and the Rat: A Color Atlas and Text

Gheorghe M. Constantinescu
April 05, 2018

Comparative Anatomy of the Mouse and Rat: a Color Atlas and Text provides detailed comparative anatomical information for those who work with mice and rats in animal research. Information is provided about  the anatomical features and landmarks for conducting a physical examination, collecting...

The Lesser Bushbaby (Galago) as an Animal Model: Selected Topics

Duane E. Haines
December 12, 2017

It is not the goal of the present volume to promote Galago as an animal model, but to alert investigators to the potential thereof. In this respect, this collection of papers serves as a general introduction. The subjects covered are purposefully broad so as to illustrate that Galago not only has...

Pathology Of Aging Rats

Burek
December 08, 2017

This study presents age-associated pathologic findings in aging rats that had been maintained under similar well-controlled laboratory conditions. The aim of the study was to evaluate two rat strains and their F1, hybrid....

CRC Handbook of Animal Models of Pulmonary Disease: Volume I

Jerome Owen Cantor
December 08, 2017

This two-volume handbook provides important information concerning the development, implementation, evaluation, uses, advantages, and limitations of a wide variety of animal model of pulmonary disease. While the work focuses on stepwise procedures for inducing and quantifying disease, additional...

Handbook of Animal Models of Renal Failure

Stephen R. Ash
November 29, 2017

This text presents a variety of methods of creation of renal failure, by the author�s experience in the study and support of laboratory animal models of renal failure. This text also discusses three studies on the mechanisms of renal damage and renal failure in animal models....

CRC Handbook of Animal Models of Pulmonary Disease: Volume II

Jerome Owen Cantor
November 29, 2017

This two-volume handbook provides important information concerning the development, implementation, evaluation, uses, advantages, and limitations of a wide variety of animal model of pulmonary disease. While the work focuses on stepwise procedures for inducing and quantifying disease, additional...

A Primate Model for the Study of Colitis and Colonic Carcinoma The Cotton-Top Tamarin (Saguinus oedipus)

Neal K. Clapp
November 29, 2017

A Primate Model for the Study of Colitis and Colonic Carcinoma describes recent observations of the prevalence, pathogenesis, natural history, and time-course of idiopathic colitis and colonic carcinoma in the Cotton-Top Tamarin (CTT) model. Results of colonoscopy and mucosal biopsy are shown to...

The Nude Mouse in Oncology Research

Epie Boven
November 29, 2017

The nude, athymic mouse (nu/nu) has become generally accepted as a valuable tool to study the biology and therapy of human cancers. This volume presents a critical review of the scientific merits of the animal as a recipient of human tumor tissue transplants. Important information is provided...

The Clinical Chemistry of Laboratory Animals

David M. Kurtz, Gregory S. Travlos
October 19, 2017

Extensively updated and expanded since the publication of Walter F. Loeb and Fred W. Quimby’s second edition in 1999, the new The Clinical Chemistry of Laboratory Animals, Third Edition continues as the most comprehensive reference on in vivo animal studies. By organizing the book into species- and...

Principles of Animal Extrapolation (1991)

Edward J. Calabrese
September 20, 2017

Principles of Animal Extrapolation addresses the conceptual basis for animal extrapolation and provides an abundance of documentation that illustrates how these principles may be applied in the selection of the more appropriate models and in the interpretation of toxicological studies. The book...

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