Life Science

Genetics

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Genetics, Genomics and Breeding of Potato

James M. Bradeen, Chittaranjan Kole
September 12, 2017

In this volume, world leaders in potato research review historical and contemporary discoveries resulting in a range of advances. Topics include nutritional quality, yield, disease and insect resistance, processing, plant growth and development, and other aspects. The book also examines research...

RNAi Technology

R. K. Gaur, Yedidya Gafni, P. Sharma, V. K. Gupta
September 12, 2017

RNAi technology is used for large-scale screens that systematically shut down each gene in the cell, which can help identify the components necessary for a particular cellular process or an event such as cell division. Exploitation of the pathway is also a promising tool in biotechnology and...

A Guide to Bioethics

Emmanuel A. Kornyo
September 07, 2017

Solving intractable biotechnological questions of evolution, medicine, and genetics is now easier due to methods permitting the rapid analysis of molecular sequence data. These advances have exposed ethical and policy concerns. How would genomic information be used and by whom? Should individuals...

Oil Palm Breeding: Genetics and Genomics

Aik Chin Soh, Sean Mayes, Jeremy A. Roberts
August 16, 2017

The oil palm is a remarkable crop, producing around 40% of the world’s vegetable oil from around 6% of the land devoted to oil crops. Conventional breeding has clearly been the major focus of genetic improvement in this crop. A mix of improved agronomy and management, coupled with breeding...

Telomeres, Diet and Human Disease: Advances and Therapeutic Opportunities

Amelia Marti, Guillermo Zalba
August 16, 2017

The maintenance of telomeres—repetitive sequences at the end of chromosome—is essential to health. Dysfunction in telomere maintenance pathways plays a role in aging, cancer, atherosclerosis and other diseases. This has led to telomere maintenance as a prime target for patient therapies. This book...

Handbook of Nucleic Acid Purification

Dongyou Liu
June 16, 2017

An Indispensable Roadmap for Nucleic Acid Preparation Although Friedrich Miescher described the first isolation of nucleic acid in 1869, it was not until 1953 that James Watson and Francis Crick successfully deciphered the structural basis of DNA duplex. Needless to say, in the years since,...

Principles and Practices of Plant Genomics, Volume 3: Advanced Genomics

Chittaranjan Kole, Albert G. Abbott
June 14, 2017

This book presents the basic and applied aspects of sequencing of genes and genomes and their implication in the fine-scale elucidation of the plant genomes. The third volume presents an overview on the advances of plant genomics made in the past century; deliberations on the genomics...

Regulation of Gene Expression by Small RNAs

Rajesh K. Gaur, John J. Rossi
May 31, 2017

New Findings Revolutionize Concepts of Gene Function Endogenous small RNAs have been found in various organisms, including humans, mice, flies, worms, fungi, and bacteria. Furthermore, it’s been shown that microRNAs acting as cellular rheostats have the ability to modulate gene expression. In...

Genomes 4

T. A. Brown
May 24, 2017

Genomes 4 has been completely revised and updated. It is a thoroughly modern textbook about genomes and how they are investigated. As with Genomes 3, techniques come first, then genome anatomies, followed by genome function, and finally genome evolution.  The...

Three Daughters, Three Journeys: Quest for Cancer Cure

Jill Charles, Indrani Mondal, Ranjita Chattopadhyay, Ananda Chakrabarty
May 10, 2017

Cancer threatens the lives of people around the world. Women, in particular, are at risk of certain cancers with a genetic cause. Certain mutations in the BRCA1 and BRCA2 genes put mothers and daughters at risk of breast and ovarian cancers. Unlike many cancers that most commonly occur after age 60...

Cancer Genetics and Genomics for Personalized Medicine

Il-Jin Kim
April 18, 2017

This book covers almost all fields of cancer genetics and genomics for personalized medicine. Targeted therapy, or precision medicine, or personalized medicine is becoming a standard treatment for many diseases, including cancer. However, how much do we know about the personalized medicine approach...

Phylogenomic Data Acquisition: Principles and Practice

W. Bryan Jennings
November 23, 2016

Phylogenomics is a rapidly growing field of study concerned with using genome-wide data—usually in the form of DNA sequence loci—to infer the evolution of genes, genomes, and the Tree of Life. Accordingly, this discipline connects many areas in biology including molecular and genomic evolution,...

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