Life Science

Genetics

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A Century of Geneticists: Mutation to Medicine

1st Edition

Krishna Dronamraju
November 12, 2018

Genetics, like all scientific disciplines, is a human endeavor. Thus, the lives of geneticists - their friendships, colleagues and associations - play an important role in the historical development of the science. This book summarizes the history of genetics by reviewing the lives of the prominent...

Precision Medicine in Cancers and Non-Communicable Diseases

1st Edition

Debmalya Barh
October 02, 2018

The availability of human genome, large amount of data on individual genetic variations, environmental interactions, influence of lifestyle, and cutting-edge tools and technologies for big-data analysis have led to the era of clinical practice of "Precision Medicine". This book aims to provide a...

The Modulation of DNA Content: Endopolyploidy, Polyteny, Aneuploidy and Chromatin Diminution

1st Edition

T. Ryan Gregory, Jillian D. Bainard
September 26, 2018

This book reviews various ways DNA content is modulated in the cells of multicellular organisms. Although the processes of endopolyploidy, polyteny, aneuploidy, and chromatin diminution have been observed for well over a century, their biological significance has not been appreciated due to the...

Nucleosome Dynamics in Epigenetic Regulation

1st Edition

Cizhong Jiang, Min Li, Jiannan Lin
September 15, 2018

The topic of nucleosome dynamics is of exceptional current interest in a number of subfields of modern biology, including molecular biology, structural biology, cell biology, systems biology and biophysics. Changes in nucleosome structure are necessary to regulate DNA repair and for the regulation...

Essential Experimental Evolution

1st Edition

Frank Rosenzweig, Gavin Sherlock
September 15, 2018

Experiments using microbes are the best way to make sense of evolution in real time. This edited book highlights the experimental approach, using Viruses, Bacteria, “lower” Eukaryotes and digital organisms. The contributors illustrate the ways this approach is revolutionizing our understanding of...

DNA Repair and Replication: Mechanisms and Clinical Significance

1st Edition

Roger J. A. Grand, John J. Reynolds
September 04, 2018

DNA Repair and Replication brings together contributions from active researchers. The first part of this book covers most aspects of the DNA damage response, emphasizing the relationship to replication stress. The second part concentrates on the relevance of this to human disease, with particular...

The Role of Intellectual Property Rights in Agriculture and Allied Sciences

1st Edition

Chandan Roy
July 31, 2018

This important volume provides a basic understanding of the different forms of intellectual property rights in agricultural science. It provides an abundance of information on the use of IP laws in agriculture and allied subjects and their proper implementation in real-life practice. The chapter...

A Probabilistic Model of the Genotype/Phenotype Relationship: Does Life Play the Dice?

1st Edition

Jean-Pierre Hugot
July 24, 2018

A Probabilistic Model of the Genotype/Phenotype Relationship provides a new hypothesis on the relationship between genotype and phenotype. The main idea of the book is that this relationship is probabilistic, in other words, the genotype does not fully explain the phenotype. This idea is developed...

Advances in Molecular Techniques

1st Edition

Rakesh S. Sengar, Amit Kumar, Reshu Chaudhary, Ashu Singh
May 17, 2018

Molecular genetics aims to comprehend biological activity at the gene sub-level. Scientists from different areas of research and applied science can use the standard techniques optimized by molecular biologists.This book serves as a guide that introduces classic molecular biology techniques and...

MicroRNA: Perspectives in Health and Diseases

1st Edition

Jaishree Paul, Rohini Muthuswami
March 01, 2018

This book explores the role of miRNA as therapeutic agents, the progress made in this direction and the problems that need to be addressed for miRNA based therapies to become successful. It also discusses the basic biology of miRNA sythesis, regulation, and their role in disease biology....

Cilia: Development and Disease

1st Edition

Paraskevi Goggolidou
February 28, 2018

The scope of the book is to highlight the diverse roles of cilia in human development and disease. Almost all cell types form cilia and although they were first detected about 200 years ago, their significance was unclear. In the past ten years, it has become obvious that cilia have got sensory...

Somatic Gene Therapy

1st Edition

P.L. Chang
December 08, 2017

As human gene therapy becomes a clinical reality, a new era in medicine dawns. Novel and innovative developments in molecular genetics now provide opportunities to treat the genetic bases of diseases often untreatable before. Somatic Gene Therapy documents these historical clinical trials, reviews...

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