Life Science


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Companion Diagnostics (CDx) in Precision Medicine

1st Edition

Il-Jin Kim
March 04, 2019

There is a new trend in anti-cancer therapeutics development: a targeted therapy and precision medicine that targets a subgroup of patients with specific biomarkers. An in vitro diagnostic (IVD) assay is required to identify a subgroup of cancer patients who would benefit from the targeted therapy,...

Revival: Pharmacological Regulation of Gene Expression in the CNS Towards an Understanding of Basal Ganglial Functions (1996)

1st Edition

Kalpana Merchant
February 20, 2019

This book focuses on dopamine-mediated regulation of gene expression within the striatum and associated regions of the central nervous system. It is an excellent review of experimental data on interactions between neuronal systems at systemic, cellular, and molecular levels. Each of the chapters,...

Revival: Topology and Physics of Circular DNA (1992)

1st Edition

Alexander Vologodskii
February 20, 2019

Topology and Physics of Circular DNA presents comprehensive coverage of the physical properties of circular DNA. The author examines how topological constraints arising from cyclization of DNA lead to distinctive properties that make closed molecules radically different from linear DNA. The...

The Human Genome in Health and Disease: A Story of Four Letters

1st Edition

Tore Samuelsson
February 04, 2019

The human genome is a linear sequence of roughly 3 billion bases and information regarding this genome is accumulating at an astonishing rate. Inspired by these advances, The Human Genome in Health and Disease: A Story of Four Letters explores the intimate link between sequence information and...

Human Molecular Genetics

5th Edition

Tom Strachan, Andrew Read
December 04, 2018

Human Molecular Genetics has been carefully crafted over successive editions to provide an authoritative introduction to the molecular aspects of human genetics, genomics and cell biology.Maintaining the features that have made previous editions so popular, this fifth edition has been completely...

Protocols for Cytogenetic Mapping of Arthropod Genomes

1st Edition

Igor V. Sharakhov
November 21, 2018

Arthropods are important to worldwide agriculture, food safety, human health, and energy production. Besides their practical significance, various species represent excellent model systems for biological investigations of evolution, development, physiology, reproduction, and social interaction. For...

A Century of Geneticists: Mutation to Medicine

1st Edition

Krishna Dronamraju
November 15, 2018

Genetics, like all scientific disciplines, is a human endeavor. Thus, the lives of geneticists - their friendships, colleagues and associations - play an important role in the historical development of the science. This book summarizes the history of genetics by reviewing the lives of the prominent...

Precision Medicine in Cancers and Non-Communicable Diseases

1st Edition

Debmalya Barh
October 02, 2018

The availability of human genome, large amount of data on individual genetic variations, environmental interactions, influence of lifestyle, and cutting-edge tools and technologies for big-data analysis have led to the era of clinical practice of "Precision Medicine". This book aims to provide a...

DNA Repair and Replication: Mechanisms and Clinical Significance

1st Edition

Roger J. A. Grand, John J. Reynolds
September 04, 2018

DNA Repair and Replication brings together contributions from active researchers. The first part of this book covers most aspects of the DNA damage response, emphasizing the relationship to replication stress. The second part concentrates on the relevance of this to human disease, with particular...

The Role of Intellectual Property Rights in Agriculture and Allied Sciences

1st Edition

Chandan Roy
July 31, 2018

This important volume provides a basic understanding of the different forms of intellectual property rights in agricultural science. It provides an abundance of information on the use of IP laws in agriculture and allied subjects and their proper implementation in real-life practice. The chapter...

A Probabilistic Model of the Genotype/Phenotype Relationship: Does Life Play the Dice?

1st Edition

Jean-Pierre Hugot
July 24, 2018

A Probabilistic Model of the Genotype/Phenotype Relationship provides a new hypothesis on the relationship between genotype and phenotype. The main idea of the book is that this relationship is probabilistic, in other words, the genotype does not fully explain the phenotype. This idea is developed...

Advances in Molecular Techniques

1st Edition

Rakesh S. Sengar, Amit Kumar, Reshu Chaudhary, Ashu Singh
May 17, 2018

Molecular genetics aims to comprehend biological activity at the gene sub-level. Scientists from different areas of research and applied science can use the standard techniques optimized by molecular biologists.This book serves as a guide that introduces classic molecular biology techniques and...