Life Science


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Somatic Gene Therapy

P.L. Chang
December 08, 2017

As human gene therapy becomes a clinical reality, a new era in medicine dawns. Novel and innovative developments in molecular genetics now provide opportunities to treat the genetic bases of diseases often untreatable before. Somatic Gene Therapy documents these historical clinical trials, reviews...

Standing on the Shoulders of Darwin and Mendel: Early Views of Inheritance

David J. Galton
October 30, 2017

This book explores early theories about the mechanisms of inheritance. Beginning with Charles Darwin's now rejected Gemmule hypothesis, the book documents the reception of Gregor Mendel's work on peas and follows the work of early 20th century scholars. The research of Francis Galton, a cousin of...

Topology and Physics of Circular DNA (1992)

Alexander Vologodskii
October 02, 2017

Topology and Physics of Circular DNA presents comprehensive coverage of the physical properties of circular DNA. The author examines how topological constraints arising from cyclization of DNA lead to distinctive properties that make closed molecules radically different from linear DNA. The...

Sexual Differentiation of the Brain (2000)

Akira Matsumoto
October 02, 2017

Sexual difference in the brain has long been one of the more intriguing research areas in the field of neuroscience. This thorough and comprehensive text uncovers and explains recent neurobiological and molecular biological studies in the field of neuroscience as they relate to the mechanisms...

Handbook of Growth Factors (1994): Volume 1

Enrique Pimentel
October 02, 2017

Volume I of this book provides a comprehensive discussion of the factors involved in regulation of the cell cycle, the general biological properties of growth factors, and the receptor and postreceptor mechanisms of action of these signaling agents. It evaluates the possible role of growth factors...

Pharmacological Regulation of Gene Expression in the CNS Towards an Understanding of Basal Ganglial Functions (1996)

Kalpana Merchant
September 28, 2017

This book focuses on dopamine-mediated regulation of gene expression within the striatum and associated regions of the central nervous system. It is an excellent review of experimental data on interactions between neuronal systems at systemic, cellular, and molecular levels. Each of the chapters,...

Genetics, Genomics and Breeding of Potato

James M. Bradeen, Chittaranjan Kole
September 12, 2017

In this volume, world leaders in potato research review historical and contemporary discoveries resulting in a range of advances. Topics include nutritional quality, yield, disease and insect resistance, processing, plant growth and development, and other aspects. The book also examines research...

RNAi Technology

R. K. Gaur, Yedidya Gafni, P. Sharma, V. K. Gupta
September 12, 2017

RNAi technology is used for large-scale screens that systematically shut down each gene in the cell, which can help identify the components necessary for a particular cellular process or an event such as cell division. Exploitation of the pathway is also a promising tool in biotechnology and...

A Guide to Bioethics

Emmanuel A. Kornyo
September 07, 2017

Solving intractable biotechnological questions of evolution, medicine, and genetics is now easier due to methods permitting the rapid analysis of molecular sequence data. These advances have exposed ethical and policy concerns. How would genomic information be used and by whom? Should individuals...

Oil Palm Breeding: Genetics and Genomics

Aik Chin Soh, Sean Mayes, Jeremy A. Roberts
August 16, 2017

The oil palm is a remarkable crop, producing around 40% of the world’s vegetable oil from around 6% of the land devoted to oil crops. Conventional breeding has clearly been the major focus of genetic improvement in this crop. A mix of improved agronomy and management, coupled with breeding...

Telomeres, Diet and Human Disease: Advances and Therapeutic Opportunities

Amelia Marti, Guillermo Zalba
August 16, 2017

The maintenance of telomeres—repetitive sequences at the end of chromosome—is essential to health. Dysfunction in telomere maintenance pathways plays a role in aging, cancer, atherosclerosis and other diseases. This has led to telomere maintenance as a prime target for patient therapies. This book...

Biological Variation in Health and Illness: Race, Age, and Sex Differences

Theresa Overfield
July 13, 2017

Specifically for the health professional, this book contains an extensive compilation of research findings on biologic variation by race, age, and gender relating to health and illness. Completely rewritten, revised, and updated, the Second Edition includes an increased discussion of biologic...