This book bridges the gap between advances in basic biology and chemistry and technological applications in the field of toxicity assessments. It describes areas of progress in the laboratory and clinic and discusses aspects of cellular organelles. It also covers the basic principles and applications of modern toxicological tools such as transcriptomic, proteomic, and metabolomic approaches. The recent developments on molecular modeling and systems biology are described with an eye on the future establishment of virtual cell technology. Finally the clinical implications for the understanding of acute and chronic renal toxicity are studied.
Section I
Cellular Organelle-based Renal Toxicity
Section II
Transcriptomic Approaches
Proteomic Approaches
Metabolomic Approaches
Section III
Molecular Modeling – Molecular Design
Systems Biological Approaches
Virtual Cell
Section IV
Clinical Implication of Renal Toxicology
Molecular Pathology of Renal Fibrosis
Section V
Classification of Nephrotoxicants
Biography
Kim, Sang Geon
