1st Edition

Chitin, Chitosan, Oligosaccharides and Their Derivatives Biological Activities and Applications

Edited By Se-Kwon Kim Copyright 2011
    666 Pages 257 B/W Illustrations
    by CRC Press

    Biopolymers found in marine animals and plants offer tremendous, largely untapped pharmaceutical potential. Research shows that these biopolymers can be used to combat various infectious as well as inflammatory, oxidative, and carcinogenic factors. Chitin, Chitosan, Oligosaccharides and Their Derivatives: Biological Activities and Applications covers the key aspects of these therapeutically valuable biopolymers and their derivatives, namely, their properties, sources, production, and applications in food science and technology as well as biological, biomedical, industrial, and agricultural fields.

    Contains more than 100 Tables & Figures and more than 800 References
    Written by 40 international contributors who are leading experts in the field of natural biomaterials, this book provides an overview of the sources and production of chitin and chitosan derivatives. It also covers their:

    • Physical and chemical aspects
    • Structural modifications for biomedical applications
    • Biological activities, in particular, antimicrobial, anti-inflammatory, antioxidant, antihypertensive, anticancer, and antidiabetic activities
    • Biomedical applications, including their possible implications as drug, vaccine, and gene carriers
    • Industrial and agricultural applications

    With their wide range of applications, the world is looking to biopolymers to serve as the basis for functional food- and drug development. This book is an important resource for those leading this effort.

    THE SOURCES AND PRODUCTION OF CHITIN AND CHITOSAN DERIVATIVES
    Chitin and Chitosan from Terrestrial Organisms
    Nitar Nwe, Tetsuya Furuike, and Hiroshi Tamura
    Chitin and Chitosan from Marine Organisms
    Wolfram M. Brück, John W. Slater, and Brian F. Carney
    Chitin and Chitosan from Microorganisms
    Zorica Knezevic-Jugovic, Zivomir Petronijevic, and Andrija Smelcerovic
    Enzymatic Production of Chitin from Crustacean Shell Waste
    Gyung-Hyun Jo, Ro-Dong Park, and Woo-Jin Jung
    Continuous Production of Chitooligosaccharides by Enzymatic Hydrolysis
    Se-Kwon Kim and Jae-Young Je
    Biosynthesis of Cellulose–Chitosan Composite
    Muenduen Phisalaphong, Nirun Jatupaiboon, and Jeerun Kingkaew
    PHYSICAL AND CHEMICAL ASPECTS OF CHITIN AND CHITOSAN DERIVATIVES
    Chemical Derivatization of Chitosan for Plasmid DNA Delivery: Present and Future
    Wing-Fu Lai and Marie Chin-Mi Lin
    X-Ray Diffraction Studies of Chitin, Chitosan, and Their Derivatives
    Waldemar Maniukiewicz
    Mechanical Properties of Chitosan and Chitosan–Poly(Vinyl Alcohol) Blend Films
    Masaru Matsuo, Yumiko Nakano, Teruo Nakashima, and Yuezhen Bin
    Electrostatic Properties of Chitosan
    Won Jong Kim
    Applications of Mass Spectrometry to Analyze Structure and Bioactivity of Chitooligosaccharides
    Martin G. Peter and Marcos N. Eberlin
    The Use of Various Types of NMR and IR Spectroscopy for Structural Characterization of Chitin and Chitosan
    Mohammad Reza Kasaai
    STRUCTURAL MODIFICATIONS OF CHITIN AND CHITOSAN DERIVATIVES
    Chemical Modifications of Chitosan Intended for Biomedical Applications
    Mani Prabaharan and Ashutosh Tiwari
    Enzymatic Modifications of Chitin and Chitosan
    Yong Zhao, Wan-Taek Ju, and Ro-Dong Park
    BIOLOGICAL ACTIVITIES OF CHITIN AND CHITOSAN DERIVATIVES
    Antimicrobial Activity of Chitin, Chitosan, and Their Oligosaccharides
    Joydeep Dutta and Pradip Kumar Dutta
    Anti-Inflammatory Activity of Chitin, Chitosan, and Their Derivatives
    Moon-Moo Kim and Se-Kwon Kim
    Chitosan Scaffolds for Bone Regeneration
    Riccardo A.A. Muzzarelli
    Antioxidative Activity of Chitin, Chitosan, and Their Derivatives
    Pyo-Jam Park, Sushruta Koppula, and Se-Kwon Kim
    Effects of Chitin, Chitosan, and Their Derivatives on Human Hemostasis
    Se-Kwon Kim and Won-Kyo Jung
    Antihypertensive Actions of Chitosan and Its Derivatives
    Jae-Young Je and Chang-Bum Ahn
    Anticancer Activity and Therapeutic Applications of Chitosan Nanoparticles
    Hang T. Ta, Dave E. Dunstan, and Crispin R. Dass
    Antidiabetic Activity and Cholesterol-Lowering Effect
    Chang-Suk Kong and Se-Kwon Kim
    BIOMEDICAL APPLICATIONS OF CHITIN AND CHITOSAN DERIVATIVES
    Chitin/Chitosan Oligosaccharides: Effective Substrates for Functional Analysis of Chitinases/Chitosanases
    Takayuki Ohnuma and Tamo Fukamizo
    Low-Molecular-Weight Water-Soluble Chitosan with Free Amine Group for Drug Delivery
    Mi-Kyeong Jang and Jae-Woon Nah
    Chitosan/Chitosan Derivatives as Carriers and Immunoadjuvants in Vaccine Delivery
    Suresh P. Vyas, Rishi Paliwal, and Shivani R. Paliwal
    Chitosan-Conjugated DNA Nanoparticle Delivery Systems for Gene Therapy
    R. Jayakumar, K. P. Chennazhi, S. V. Nair, Tetsuya Furuike, and Hiroshi Tamura
    Chitinolytic Enzymes from the Moderately Thermophilic Bacterium Ralstonia sp. A-471: Characterization and Application
    Mitsuhiro Ueda
    Chitosan and Chitosan Derivatives as DNA and siRNA Carriers
    Hu-Lin Jiang, Yun-Jaie Choi, Myung-Haing Cho, and Chong-Su Cho
    Metabolic Pathway of Chitin and Its Oligosaccharides in Marine Bacterium Vibrios
    Jae Kweon Park, Nemat O. Keyhani, and Saul Roseman
    Medical Applications of Chitin and Chitosan: Going Forward
    Eugene Khor
    Radiation Functionalization and Applications of Chitosan and Its Derivatives
    Maolin Zhai, Long Zhao, Ling Huang, Ling Xu, Liyong Yuan, and Min Wang
    Applications of Chitosan Oligosaccharide and Glucosamine in Dentistry
    Yoshihiko Hayashi
    Applications of Chitosan and Its Derivatives in Veterinary Medicine
    Sevda S¸enel
    INDUSTRIAL APPLICATIONS OF CHITIN AND CHITOSAN DERIVATIVES
    Separation Membranes from Chitin and Chitosan Derivatives
    Tadashi Uragami
    Hydrophobically Modified Acylated Chitosan Particles for Drug Delivery Applications: An Overview
    R. Shelma and Chandra P. Sharma
    Chitin, Chitosan, and Their Derivatives in Beverage Industry
    Aurélie Bornet and Pierre-Louis Teissedre
    Chitin Nanofibrils and Their Derivatives as Cosmeceuticals
    P. Morganti
    Chitin, Chitosan, and Their Oligosaccharides in Food Industry
    Janak K. Vidanarachchi, Maheshika S. Kurukulasuriya, and Se-Kwon Kim
    Chitin/Chitosan and Derivatives for Wastewater Treatment
    P. N. Sudha
    AGRICULTURAL AND BIOTECHNOLOGY APPLICATIONS OF CHITIN AND CHITOSAN AND THEIR DERIVATIVES
    Chitin, Chitosan Derivatives Induced the Production of Secondary Metabolites and Plant Development through In Vitro and In Vivo Techniques
    Abdul Bakrudeen Ali Ahmed and Se-Kwon Kim
    Mechanism and Application of Chitin/Chitosan and Their Derivatives in Plant Protection
    Heng Yin and Yuguang Du
    Enhancing Crop Production with Chitosan and Its Derivatives
    Nguyen Anh Dzung

    Biography

    Se-Kwon Kiro, Ph.D., Professor, Department of Chemistry Director, Marine Bioprocess Research Center, Pukyong National University, Busan, South Korea