1st Edition

Polymeric Biomaterials Structure and Function, Volume 1

Edited By Severian Dumitriu, Valentin Popa Copyright 2013
    920 Pages 404 B/W Illustrations
    by CRC Press

    920 Pages 404 B/W Illustrations
    by CRC Press

    Biomaterials have had a major impact on the practice of contemporary medicine and patient care. Growing into a major interdisciplinary effort involving chemists, biologists, engineers, and physicians, biomaterials development has enabled the creation of high-quality devices, implants, and drug carriers with greater biocompatibility and biofunctionality. The fast-paced research and increasing interest in finding new and improved biocompatible or biodegradable polymers has provided a wealth of new information, transforming this edition of Polymeric Biomaterials into a two-volume set.

    This volume, Polymeric Biomaterials: Structure and Function, contains 25 authoritative chapters written by experts from around the world. Contributors cover the following topics:

    • The structure and properties of synthetic polymers including polyesters, polyphosphazenes, and elastomers
    • The structure and properties of natural polymers such as mucoadhesives, chitin, lignin, and carbohydrate derivatives
    • Blends and composites—for example, metal–polymer composites and biodegradable polymeric/ceramic composites
    • Bioresorbable hybrid membranes, drug delivery systems, cell bioassay systems, electrospinning for regenerative medicine, and more

    Completely revised and expanded, this state-of-the-art reference presents recent developments in polymeric biomaterials: from their chemical, physical, and structural properties to polymer synthesis and processing techniques and current applications in the medical and pharmaceutical fields.

    Synthesis and Fabrication of Polyesters as Biomaterials
    Philippe Lecomte and Christine Jérôme

    Hydrogels Formed by Cross-Linked Poly(Vinyl Alcohol)
    Gaio Paradossi

    Development and Evaluation of Poly(Vinyl Alcohol) Hydrogels as a Component of Hybrid Artificial Tissues for Orthopedics Surgery Application
    Masanori Kobayashi

    Polyphosphazenes as Biomaterials
    Meng Deng, Cato T. Laurencin, Harry R. Allcock, and Sangamesh G. Kumbar

    Biodegradable Polymers as Drug Carrier Systems
    Abraham J. Domb and Wahid Khan

    Bioresorbable Hybrid Membranes for Bone Regeneration
    Akiko Obata and Toshihiro Kasuga

    Mucoadhesive Polymers: Basics, Strategies, and Future Trends
    Andreas Bernkop-Schnürch

    Biodegradable Polymeric/Ceramic Composite Scaffolds to Regenerate Bone Tissue
    Catherine Gkioni, Sander Leeuwenburgh, and John Jansen

    Amphiphilic Systems as Biomaterials Based on Chitin, Chitosan, and Their Derivatives
    Jacques Desbrieres

    Biomaterials of Natural Origin in Regenerative Medicine
    Vijay Kumar Nandagiri, Valeria Chiono, Piergiorgio Gentile, Franco Maria Montevecchi, and Gianluca Ciardelli

    Natural Polymers as Components of Blends for Biomedical Applications
    Alina Sionkowska

    Metal–Polymer Composite Biomaterials
    Takao Hanawa

    Evolution of Current and Future Concepts of Biocompatibility Testing
    Menno L.W. Knetsch

    Biocompatibility of Elastomers
    Dominique Chauvel-Lebret, Pascal Auroy, and Martine Bonnaure-Mallet

    Preparation and Applications of Modulated Surface Energy Biomaterials
    Blanca Vázquez, Luis M. Rodríguez-Lorenzo, Gema Rodríguez-Crespo, Juan Parra, Mar Fernández, and Julio San Román

    Electrospinning for Regenerative Medicine
    Toby D. Brown, Cedryck Vaquette, Dietmar W. Hutmacher, and Paul D. Dalton

    Polymeric Nanoparticles for Targeted Delivery of Bioactive Agents and Drugs
    Cesare Errico, Alberto Dessy, Anna Maria Piras, and Federica Chiellini

    Polymeric Materials Obtained through Biocatalysis
    Florin Dan Irimie, Csaba Paizs, and Monica Ioana Tosa

    Polymer-Based Colloidal Aggregates as a New Class of Drug Delivery Systems
    Cesare Cametti

    Photoresponsive Polymers for Control of Cell Bioassay Systems
    Kimio Sumaru, Shinji Sugiura, Toshiyuki Takagi, and Toshiyuki Kanamori

    Lignin in Biological Systems
    Valentin I. Popa

    Carbohydrate-Derived Self-Crosslinkable In Situ Gelable Hydrogels for Modulation of Wound Healing
    Lihui Weng, Christine Falabella, and Weiliam Chen

    Dental and Maxillofacial Surgery Applications of Polymers
    E.C. Combe

    Biomaterials as Platforms for Topical Administration of Therapeutic Agents in Cutaneous Wound Healing
    Rhiannon Braund and Natalie J. Medlicott

    Polymers for Artificial Joints
    Masayuki Kyomoto, Toru Moro, and Kazuhiko Ishihara

    Biography

    Severian Dumitriu (deceased) was a research professor in the Department of Chemical Engineering at the University of Sherbrooke, Quebec, Canada. He edited several books, including Polymeric Biomaterials, Second Edition, Polysaccharides in Medicinal Applications, and Polysaccharides: Structural Diversity and Functional Versatility. He also authored or coauthored more than 190 professional papers and book chapters in the fields of polymer and cellulose chemistry, polyfunctional initiators, and bioactive polymers and held 15 international patents. Professor Dumitriu received his BSc (1959) and MS (1961) in chemical engineering and his Ph.D. (1971) in macromolecular chemistry from the Polytechnic Institute of Jassy, Romania.

    Valentin I. Popa earned his BSc and MSc in chemical engineering (1969) and Ph.D. in the field of polysaccharide chemistry (1976) from Polytechnic Institute of Iasi, Romania. He was awarded the Romanian Academy Prize for his contributions in the field of seaweed chemistry (1976). He has published more than 500 papers in the following fields: wood chemistry and biotechnology, biomass complex processing, biosynthesis and biodegradation of natural compounds, allelochemicals, bioadhesives, and bioremediation. Dr Popa is also the author or coauthor of 37 books or book chapters. He holds six patents and has been involved in many Romanian and European research projects as scientific manager. He is also a professor of wood chemistry and biotechnology at "Gheorghe Asachi" Technical University of Iasi, and editor-in-chief of Cellulose Chemistry and Technology.

    "This book is a valuable source of data on the complex subject of polymeric biomaterials, written by world-renowned scientists with major contributions in this field and reflects the current state of knowledge of nearly the entire spectrum of polymeric biomaterials.
    —Diana Ciolacu, Cellulose Chem. Technol., 47 (5-6), 487-494 (2013)